BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE

Product Name: BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE
CAS No.: 125-51-9
Chemical Name: BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE
Synonyms: qpb;jb-323;piptal;Piptalake;Pipenzolate;PIPENZOLATE BROMIDE;pipenzolatemethobromide;PIPENZOLATE BROMIDE(SH);pipenzolatemethylbromide;XEDCWWFPZMHXCM-UHFFFAOYSA-M
CBNumber: CB0381093
Molecular Formula: C22H28BrNO3
Formula Weight: 434.37
MOL File: 125-51-9.mol

More

Less

BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Property

Melting point:: 179-180°
form: powder
color: white

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: TN5425000
Toxicity: LD50 oral in rat: 916mg/kg

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: P479853
Product name: Piptalake
Packaging: 100mg
Price: $450
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003871
Product name: PIPENZOLATE BROMIDE
Purity: 95.00%
Packaging: 10G
Price: $1275.81
Updated: 2021/12/16

AK Scientific

Product number: 2658AH
Product name: Pipenzolatebromide
Packaging: 1g
Price: $2625
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003871
Product name: PIPENZOLATE BROMIDE
Purity: 95.00%
Packaging: 50G
Price: $2677.14
Updated: 2021/12/16

Crysdot

Product number: CD31004085
Product name: Pipenzolatebromide
Purity: 98+%
Packaging: 100mg
Price: $49
Updated: 2021/12/16

More

Less

BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Chemical Properties,Usage,Production

Originator

Piptal ,Merrell National ,US ,1955

Uses

Piptalake is used in the treatment with copper-tolylterpyridine and platinum-tolylterpyridine that targets telomeres and telomerase for regulation of chromosome mis-segregation rates for cancer therapy.

Uses

antispasmodic

Manufacturing Process

N-ethyl-3-chloropiperidine was prepared according to the method of Fuson and Zirkle described in Volume 70, J. Am. Chem. Soc., p 2760. 12.0 g (0.081 mol) of N-ethyl-3-chloropiperidine was mixed with 18.6 g (0.081 mol) of benzilic acid and 80 cc of anhydrous isopropyl alcohol as a solvent. The mixture was refluxed for 72 hours. The solution was then filtered and concentrated at 30 mm of mercury. The concentrate was dissolved in water, acidified with hydrochloric acid and extracted with ether to remove theThe aqueous layer was neutralized with sodium bicarbonate and the product was extracted with ether. The ethereal solution of the product was dried with potassium carbonate, the ether was removed by distillation and the residue was distilled at 0.12 to 0.18 mm of mercury, the BP being 194° to 198°C. A yield of 16.5 g (60% of theoretical) of N-ethyl-3-piperidyl-benzilate was obtained.
34 g (0.1 mol) of the basic ester is dissolved in 75 cc of isopropyl alcohol and treated with 9.5 g (0.1 mol) of methyl bromide. The mixture is allowed to stand at room temperature until precipitation is complete. The product is removed by filtration and washed with isopropyl alcohol, yield 33 g, MP 175° to 177°C. On recrystallization from isopropyl alcohol, the MP was raised to 179° to 180°C dec.

brand name

Piptal (Marion Merrell Dow).

Therapeutic Function

Spasmolytic

BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Suppliers

China 19 Germany 1 India 2 Switzerland 1 United Kingdom 1 United States 9 Global 33

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9578
Advantage: 60

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15352
Advantage: 58

Jinan Ruisi Pharmaceutical Technology Co., LTD

Tel: 0531-69900633 18340090523
Email: changyuan20@163.com
Country: China
ProdList: 2649
Advantage: 58

Shanghai Jiegu Biotechnology Co., Ltd.

Tel: 021-51698675
Email: jiejiegroup@126.com
Country: China
ProdList: 4290
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-61856358 15229202216
Fax: 029-88380327
Email: 1020@dideu.com
Country: China
ProdList: 10011
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd.

Tel: 029-81310890 13571859809
Email: info@pushanshiye.com
Country: China
ProdList: 10000
Advantage: 58

LGC Science (Shanghai) Ltd.

Tel: 17717235263
Email: cindy.yang@lgcgroup.com
Country: China
ProdList: 15583
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: rose.shi@synzest.com
Country: China
ProdList: 6210
Advantage: 58

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 73043
Advantage: 58

Shenzhen Nexconn Pharmatechs Ltd

Tel: +86-755-89396905 +86-15013857715
Email: admin@nexconn.com
Country: China
ProdList: 10311
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Lanospharma Laboratories Co.,Ltd

Tel: --
Fax: --
Email: sales@lanospharma.com
Country: China
ProdList: 6329
Advantage: 56

BBT INC

Tel: --
Fax: --
Email: tiyfkj@hotmail.com
Country: China
ProdList: 3515
Advantage: 47

Guangzhou WeiBo Chemical Co., Ltd.

Tel: --
Fax: --
Email: weibochem@163.com
Country: China
ProdList: 6187
Advantage: 67

A.T.CHEMICAL

Tel: --
Fax: --
Email: Jeffreyxu@atchem.net
Country: China
ProdList: 6589
Advantage: 51

Shanghai New Union Textra Import & Export Co., Ltd

Tel: --
Fax: --
Email: zhou@pharmchemical.com
Country: China
ProdList: 2748
Advantage: 60

125-51-9, BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDERelated Search:

Ethyl 2-hydroxyisobutyrate Methyl DL-mandelate 3-ETHOXYPIPERIDINE (R)-(-)-Methyl mandelate Methyl benzilate (R)-(-)-2-HYDROXY-2-PHENYLPROPIONIC ACID BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE PIPERIDOLATE Methyl 2-hydroxyisobutyrate Adiphenine hydrochloride 3-METHOXYPIPERIDINE L-(+)-MANDELIC ACID ETHYL ESTER Benzilic acid (S)-(+)-2-HYDROXY-2-PHENYLPROPIONIC ACID ACETYLCHOLINE BROMIDE Benactyzine 1-ETHYL-3-HYDROXYPIPERIDINE ISOPROPYL (S)-(-)-LACTATE

PIPENZOLATE BROMIDE

1-ethyl-3-hydroxy-1-methyl-piperidiniumbromidebenzilate

1-Ethyl-3-(2-hydroxy-2,2-diphenylacetoxy)-1-methyl-1-piperidinium Bromide

1-ethyl-3-piperidylbenzilatemethylbromide

benzilicacid,1-ethyl-3-piperidylestermethylbromide

benzilicacid,esterwith1-ethyl-3-hydroxy-1-methylpiperidiniumbromide

jb-323

n-ethyl-3-piperidylbenzilatemethobromide

pipenzolatemethobromide

pipenzolatemethylbromide

XEDCWWFPZMHXCM-UHFFFAOYSA-M

piperidinium,1-ethyl-3-hydroxy-1-methyl-,bromide,benzilate

piptal

qpb

BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE

3-benziloyloxy-1-ethyl-1-methylpiperidinium bromide

pipenzolate bromide sigmaultra

Pipenzolate

PIPENZOLATEBROMIDE,ULTRAPURE

PIPENZOLATE BROMIDE(SH)

1-Ethyl-3-(2-hydroxy-2,2-diphenylacetoxy)-1-Methylpiperidin-1-iuM broMide

Piptalake

Pipenzolate BromideQ: What is Pipenzolate Bromide Q: What is the CAS Number of Pipenzolate Bromide Q: What is the storage condition of Pipenzolate Bromide

Piperidinium, 1-ethyl-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-, bromide (1:1)

125-51-9

C22H28BrNO3

C22H28NO3Br

Building Blocks

Heterocyclic Building Blocks

Piperidines

PIPTAL

Inhibitors

Building Blocks

C16 to C36

Chemical Synthesis

Heterocyclic Building Blocks

Piperidines