HOMOBUTEIN
- Product Name
- HOMOBUTEIN
- CAS No.
- 34000-39-0
- Chemical Name
- HOMOBUTEIN
- Synonyms
- HOMOBUTEIN;homobitein;HOMOBUTEIN hplc;Einecs 251-782-7;3-O-methylbutein;HOMOBUTEIN WITH HPLC;4,2',4'-Trihydroxy-3-methoxychalcone;3-METHOXY-2',4',4-TRIHYDROXYCHALCONE;2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE;(E)-2',4,4'-trihydroxy-3-methoxychalcone
- CBNumber
- CB0382919
- Molecular Formula
- C16H14O5
- Formula Weight
- 286.28
- MOL File
- 34000-39-0.mol
HOMOBUTEIN Property
- Melting point:
- 207-212°C
- Boiling point:
- 523.8±50.0 °C(Predicted)
- Density
- 1.369±0.06 g/cm3(Predicted)
- pka
- 7.43±0.35(Predicted)
- form
- Solid
- color
- Light yellow to yellow
- LogP
- 2.880 (est)
N-Bromosuccinimide Price
- Product number
- FM65711
- Product name
- 3-Methoxy-2',4',4-trihydroxychalcone
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FM65711
- Product name
- 3-Methoxy-2',4',4-trihydroxychalcone
- Packaging
- 10mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FM65711
- Product name
- 3-Methoxy-2',4',4-trihydroxychalcone
- Packaging
- 25mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- FM65711
- Product name
- 3-Methoxy-2',4',4-trihydroxychalcone
- Packaging
- 50mg
- Price
- $325
- Updated
- 2021/12/16
- Product number
- CHM0030042
- Product name
- HOMOBUTEIN
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $789.51
- Updated
- 2021/12/16
HOMOBUTEIN Chemical Properties,Usage,Production
Uses
Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation[1][2][3][4].
Definition
ChEBI: Homobutein is a member of chalcones.
IC 50
Toxoplasma
References
[1] Orlikova B, et al. Natural chalcones as dual inhibitors of HDACs and NF-κB. Oncol Rep. 2012 Sep;28(3):797-805. DOI:10.3892/or.2012.1870
[2] Adeyemi OS, et al. In Vitro Screening to Identify Anti-Toxoplasma Compounds and In Silico Modeling for Bioactivities and Toxicity. Yale J Biol Med. 2019 Sep 20;92(3):369-383. PMID:31543702
[3] Yenesew A, et al. Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica. Phytochemistry. 2004 Nov;65(22):3029-32. DOI:10.1016/j.phytochem.2004.08.050
[4] Serobatse K, et al. Antioxidant and antimalarial properties of butein and homobutein based on their ability to chelate iron (II and III) cations: a DFT study in vacuo and in solution. European Food Research and Technology, 2016, 242(1): 71-90.
HOMOBUTEIN Preparation Products And Raw materials
Raw materials
Preparation Products
HOMOBUTEIN Suppliers
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- 021-61259108 18621169109
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- 86-21-61259102
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- China
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- +49 5662 4087320
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- Germany
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- +86-27-84254680
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- QQ:3008007432
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
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View Lastest Price from HOMOBUTEIN manufacturers
- Product
- HOMOBUTEIN 34000-39-0
- Price
- US $302.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2018-07-27