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HOMOBUTEIN

Product Name: HOMOBUTEIN
CAS No.: 34000-39-0
Chemical Name: HOMOBUTEIN
Synonyms: HOMOBUTEIN;homobitein;HOMOBUTEIN hplc;Einecs 251-782-7;3-O-methylbutein;HOMOBUTEIN WITH HPLC;4,2',4'-Trihydroxy-3-methoxychalcone;3-METHOXY-2',4',4-TRIHYDROXYCHALCONE;2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE;(E)-2',4,4'-trihydroxy-3-methoxychalcone
CBNumber: CB0382919
Molecular Formula: C16H14O5
Formula Weight: 286.28
MOL File: 34000-39-0.mol

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HOMOBUTEIN Property

Melting point:: 207-212°C
Boiling point:: 523.8±50.0 °C(Predicted)
Density: 1.369±0.06 g/cm3(Predicted)
pka: 7.43±0.35(Predicted)
form: Solid
color: Light yellow to yellow
LogP: 2.880 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FM65711
Product name: 3-Methoxy-2',4',4-trihydroxychalcone
Packaging: 5mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM65711
Product name: 3-Methoxy-2',4',4-trihydroxychalcone
Packaging: 10mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM65711
Product name: 3-Methoxy-2',4',4-trihydroxychalcone
Packaging: 25mg
Price: $175
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM65711
Product name: 3-Methoxy-2',4',4-trihydroxychalcone
Packaging: 50mg
Price: $325
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0030042
Product name: HOMOBUTEIN
Purity: 95.00%
Packaging: 10MG
Price: $789.51
Updated: 2021/12/16

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HOMOBUTEIN Chemical Properties,Usage,Production

Uses

Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation[1][2][3][4].

Definition

ChEBI: Homobutein is a member of chalcones.

IC 50

Toxoplasma

References

[1] Orlikova B, et al. Natural chalcones as dual inhibitors of HDACs and NF-κB. Oncol Rep. 2012 Sep;28(3):797-805. DOI:10.3892/or.2012.1870
[2] Adeyemi OS, et al. In Vitro Screening to Identify Anti-Toxoplasma Compounds and In Silico Modeling for Bioactivities and Toxicity. Yale J Biol Med. 2019 Sep 20;92(3):369-383. PMID:31543702
[3] Yenesew A, et al. Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica. Phytochemistry. 2004 Nov;65(22):3029-32. DOI:10.1016/j.phytochem.2004.08.050
[4] Serobatse K, et al. Antioxidant and antimalarial properties of butein and homobutein based on their ability to chelate iron (II and III) cations: a DFT study in vacuo and in solution. European Food Research and Technology, 2016, 242(1): 71-90.

HOMOBUTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from HOMOBUTEIN manufacturers

Career Henan Chemical Co

Product: HOMOBUTEIN 34000-39-0
Price: US $302.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2018-07-27

34000-39-0, HOMOBUTEINRelated Search:

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HOMOBUTEIN

(E)-2',4,4'-trihydroxy-3-methoxychalcone

3-O-methylbutein

HOMOBUTEIN WITH HPLC

HOMOBUTEIN hplc

(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one

4,2',4'-Trihydroxy-3-methoxychalcone

Einecs 251-782-7

2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE

3-METHOXY-2',4',4-TRIHYDROXYCHALCONE

2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-, (2E)-

homobitein

(E)-1-(2，4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one

34000-39-0

Chalcones