ChemicalBook > CAS DataBase List > Phenetidine

Phenetidine

Product Name
Phenetidine
CAS No.
156-43-4
Chemical Name
Phenetidine
Synonyms
P-PHENETIDINE;4-ETHOXYANILINE;PARA PHENETIDINE;ethoxyaniline;Benzenamine, 4-ethoxy-;p-Phenetidin;P-ETHOXYANILINE;PARA-PHENETIDIN;p-Phenetidine,98%;Aniline, p-ethoxy-
CBNumber
CB0386144
Molecular Formula
C8H11NO
Formula Weight
137.18
MOL File
156-43-4.mol
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Phenetidine Property

Melting point:
2-5 °C(lit.)
Boiling point:
250 °C(lit.)
Density 
1.065 g/mL at 25 °C(lit.)
vapor pressure 
2.93Pa at 25℃
refractive index 
n20/D 1.559(lit.)
Flash point:
240 °F
storage temp. 
2-8°C
solubility 
20g/l
form 
A liquid
pka
5.2(at 28℃)
color 
Clear Yellow
PH
8 (1g/l, H2O, 20℃)
Water Solubility 
practically insoluble
Sensitive 
Air Sensitive
Merck 
14,7228
BRN 
606666
Dielectric constant
7.3(21℃)
Stability:
Stable, but light and air sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKey
IMPPGHMHELILKG-UHFFFAOYSA-N
CAS DataBase Reference
156-43-4(CAS DataBase Reference)
NIST Chemistry Reference
4-Ethoxyaniline(156-43-4)
EPA Substance Registry System
p-Phenetidine (156-43-4)
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Safety

Hazard Codes 
T,Xi,Xn
Risk Statements 
23/24/25-33-68-43-36-20/21/22
Safety Statements 
28-36/37-45-46
RIDADR 
UN 2311 6.1/PG 3
WGK Germany 
1
RTECS 
SI6465500
8-10
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29222200
Toxicity
LD50 orl-rat: 580 mg/kg GISAAA 35(8),28,70
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P14815
Product name
4-Ethoxyaniline
Purity
98%
Packaging
100g
Price
$59.7
Updated
2024/03/01
Sigma-Aldrich
Product number
P14815
Product name
4-Ethoxyaniline
Purity
98%
Packaging
500g
Price
$212
Updated
2024/03/01
TCI Chemical
Product number
P0090
Product name
p-Phenetidine
Purity
>98.0%(GC)
Packaging
25g
Price
$48
Updated
2024/03/01
TCI Chemical
Product number
P0090
Product name
p-Phenetidine
Purity
>98.0%(GC)
Packaging
500g
Price
$167
Updated
2024/03/01
TRC
Product number
P296300
Product name
p-Phenetidine
Packaging
100g
Price
$1205
Updated
2021/12/16
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Phenetidine Chemical Properties,Usage,Production

Chemical Properties

colourless liquid

Uses

A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.

Definition

ChEBI: An aromatic ether that is aniline in which the hydrogen at position 4 is replaced by an ethoxy group. It is a hydrolysis metabolite of phenacetin.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 27, p. 347, 1984 DOI: 10.1021/jm00369a019

General Description

Colorless to dark red liquid.

Air & Water Reactions

Very sensitive to exposure to air and light. Turns red to brown on exposure to light and air. . Slightly soluble in water.

Reactivity Profile

Phenetidine reacts vigorously with powerful oxidizers.

Fire Hazard

Phenetidine is combustible.

Safety Profile

Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. Caution: It can be absorbed through the skin. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

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View Lastest Price from Phenetidine manufacturers

Hebei Guanlang Biotechnology Co,.LTD
Product
Phenetidine 156-43-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2023-05-10
Hebei Guanlang Biotechnology Co., Ltd.
Product
Phenetidine 156-43-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-11-18
Baoji Guokang Healthchem co.,ltd
Product
Phenetidine 156-43-4
Price
US $16.00/KG
Min. Order
1公斤
Purity
99%
Supply Ability
10TONS
Release date
2021-06-07

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