3-CHLORO-2-IODOPHENOL
- Product Name
- 3-CHLORO-2-IODOPHENOL
- CAS No.
- 858854-82-7
- Chemical Name
- 3-CHLORO-2-IODOPHENOL
- Synonyms
- 3-Choro-2-iodophenol;3-CHLORO-2-IODOPHENOL;Phenol, 3-chloro-2-iodo-
- CBNumber
- CB0390983
- Molecular Formula
- C6H4ClIO
- Formula Weight
- 254.45
- MOL File
- 858854-82-7.mol
3-CHLORO-2-IODOPHENOL Property
- Melting point:
- 56 °C
- Boiling point:
- 225.6±20.0 °C(Predicted)
- Density
- 2.087±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 7.55±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C382025
- Product name
- 3-Chloro-2-iodophenol
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- AK151227
- Product name
- 3-Chloro-2-iodophenol
- Purity
- 97+%
- Packaging
- 100mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- Z0905
- Product name
- 3-Choro-2-iodophenol
- Packaging
- 250mg
- Price
- $124
- Updated
- 2021/12/16
- Product number
- HCH0063561
- Product name
- 3-CHLORO-2-IODOPHENOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.18
- Updated
- 2021/12/16
- Product number
- 858854827
- Product name
- 3-Chloro-2-iodophenol
- Packaging
- 1g
- Price
- $513.32
- Updated
- 2021/12/16
3-CHLORO-2-IODOPHENOL Chemical Properties,Usage,Production
Synthesis
863870-77-3
858854-82-7
Step 3: Sodium hydroxide (32.0 g, 800 mmol) was slowly added to a 400 mL ethanol solution containing 3-chloro-2-iodophenyl N,N-diethylcarbamate (57.0 g, 161 mmol) at 25 °C. The reaction mixture was heated to reflux and maintained for 2 hours. Upon completion of the reaction, the ethanol solvent was removed by distillation under reduced pressure. The residue was dissolved in 400 mL of water and subsequently extracted with petroleum ether. The aqueous phase was neutralized with 2N hydrochloric acid solution and extracted with ethyl acetate. All organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate. Finally, the organic solvent was removed by distillation under reduced pressure to afford the target product 3-chloro-2-iodophenol (41.0 g, quantitative yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 5.58 (brs, 1H), 6.90 (dd, J = 1.2,8.4 Hz, 1H), 7.06 (dd, J = 1.2,8.0 Hz, 1H), 7.21 (t, J = 8.0 Hz, 1H).
References
[1] Patent: US2017/145005, 2017, A1. Location in patent: Paragraph 0368; 0375; 0376; 0377
[2] Journal of Organic Chemistry, 2005, vol. 70, # 16, p. 6548 - 6551
[3] Journal of Organic Chemistry, 2007, vol. 72, # 14, p. 5113 - 5118
[4] Organic and Biomolecular Chemistry, 2010, vol. 8, # 17, p. 3860 - 3864
[5] Journal of Organic Chemistry, 2011, vol. 76, # 9, p. 3416 - 3437
3-CHLORO-2-IODOPHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
3-CHLORO-2-IODOPHENOL Suppliers
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- United States
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- sales@3bsc.com
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- United States
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View Lastest Price from 3-CHLORO-2-IODOPHENOL manufacturers
- Product
- 3-CHLORO-2-IODOPHENOL 858854-82-7
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08