ChemicalBook > CAS DataBase List > BOC-D-Phenylalanine

BOC-D-Phenylalanine

Product Name
BOC-D-Phenylalanine
CAS No.
18942-49-9
Chemical Name
BOC-D-Phenylalanine
Synonyms
BOC-D-PHE-OH;BOC-D-PHE;(R)-2-((tert-butoxycarbonyl)aMino)-3-phenylpropanoic acid;N-(TERT-BUTOXYCARBONYL)-D-PHENYLALANINE;Boc-D-Phe-OH ,≥99%;BC-D-phenylalanine;BOC-D-PHENYLALANINE;RARECHEM AL BE 0806;N-BOC-D-PHENYLALANINE;BOC-D-PHENYLALANINE-OH
CBNumber
CB0397472
Molecular Formula
C14H19NO4
Formula Weight
265.3
MOL File
18942-49-9.mol
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BOC-D-Phenylalanine Property

Melting point:
78-87 °C
alpha 
-26 º (c=2,ethanol)
Boiling point:
408.52°C (rough estimate)
Density 
1.1356 (rough estimate)
refractive index 
-25 ° (C=1, EtOH)
storage temp. 
2-8°C
solubility 
DMSO, Ethanol, Methanol
pka
3.88±0.10(Predicted)
form 
Fine Crystalline Powder
color 
White
optical activity
[α]20/D 25±1°, c = 1% in ethanol
Water Solubility 
insoluble
BRN 
3593396
InChIKey
ZYJPUMXJBDHSIF-LLVKDONJSA-N
CAS DataBase Reference
18942-49-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HS Code 
29242990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.53094
Product name
Boc-D-Phe-OH
Purity
Novabiochem?
Packaging
25g
Price
$96.9
Updated
2024/03/01
Sigma-Aldrich
Product number
15484
Product name
Boc-D-Phe-OH
Purity
≥99.0% (sum of enantiomers, TLC)
Packaging
5g
Price
$27.18
Updated
2024/03/01
Sigma-Aldrich
Product number
8.53094
Product name
Boc-D-Phe-OH
Purity
Novabiochem?
Packaging
100g
Price
$199
Updated
2023/06/20
TCI Chemical
Product number
B2989
Product name
N-(tert-Butoxycarbonyl)-D-phenylalanine
Purity
>98.0%(T)
Packaging
5g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
B2989
Product name
N-(tert-Butoxycarbonyl)-D-phenylalanine
Purity
>98.0%(T)
Packaging
25g
Price
$40
Updated
2024/03/01
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BOC-D-Phenylalanine Chemical Properties,Usage,Production

Description

BOC-D-Phenylalanine is the BOC (tert-butyloxycarbonyl) protected form of D-phenylalanine. It can be used in the synthesis of benzo[de][1,7] napthyridinones as PARP1 inhibitors. It is also an important reagent during the manufacturing of proline-containing, ß-turn mimetic cycle tetrapeptides.

Chemical Properties

white fine crystalline powder

Uses

Boc-D-Phenylalanine is used in the synthesis of benzo[de][1,7]napthyridinones as PARP1 inhibitors. Also it is an important reagent in the preparation of proline-containing, β-turn mimetic cycle tetrapeptides.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

References

https://www.clearsynth.com/en/CST07663.html
http://www.biocompare.com/Protein-Biochemistry/10318-Boc-Protected-Phenylalanine-Monomers-and-Derivatives/

BOC-D-Phenylalanine Preparation Products And Raw materials

Raw materials

L-Phenylalanine 1,4-Dioxane

Preparation Products

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View Lastest Price from BOC-D-Phenylalanine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
BOC-D-Phenylalanine 18942-49-9
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-12-02
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-D-Phe-OH 18942-49-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%, 99%
Supply Ability
1T+
Release date
2023-09-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
BOC-D-Phenylalanine 18942-49-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

18942-49-9, BOC-D-PhenylalanineRelated Search:

N-Carbobenzyloxyglycine L-Phenylalanine Phenprobamate 1,1'-Carbonyldiimidazole tert-Butanol tert-Butyl carbazate D-Phenylalanine DL-Phenylalanine N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Bortezomib Impurity 45 1-Chloro-2-methylpropane Bortezomib Impurity 5 tert-Butyl Tosylate DISCONTINUED Bortezomib Impurity 23 Bortezomib Impurity 35 2,3-Pyrazinedicarboxylic acid 1-Bromo-2-methylpropane Bortezomib Impurity 47 HCl

  • BOC-D-PHE
  • BOC-D-PHE-OH
  • BOC-D-PHENYLALANINE
  • (R)-2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID
  • N-T-BOC-D-PHENYLALANINE
  • N-(TERT-BUTOXYCARBONYL)-D-PHENYLALANINE
  • Boc-D-phenylalanine≥ 99% (HPLC)
  • N-ALPHA-TERT-BUTYLOXYCARBONYL-D-PHENYLALANINE
  • N-ALPHA-T-BUTYLOXYCARBONYL-D-PHENYLALANINE
  • N-ALPHA-T-BOC-D-PHENYLALANINE
  • N-BOC-D-PHENYLALANINE
  • Boc-D-Phe-OH >=99.0% (sum of enantiomers, TLC)
  • (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
  • N-[-(1,1-DIMETHYLETHOXY)-CARBONYL]-D-PHENYLAMINE
  • T-BUTYLOXYCARBONYL-D-PHENYLALANINE
  • RARECHEM AL BE 0806
  • BOC-D-Phenylalanine, 99+%
  • N-[-(1,1-DIMETHYLETHOXY)-CARBONYL]-D-PHENYLALANINE
  • BOC-D-PHENYLALANINE-OH
  • Boc-D-Phe-OH ,≥99%
  • N-Boc-D-phenylalanine, 98+%
  • N-t-Butoxycarbonyl-D-phenylalanine
  • N-Boc-D-phenylalanine Boc-D-Phe-OH
  • (R)-2-((tert-butoxycarbonyl)aMino)-3-phenylpropanoic acid
  • (Tert-Butoxy)Carbonyl D-Phe-OH
  • Bortezomib Impurity 28
  • 2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-phenylpropanoate
  • (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoic acid
  • N-(tert-Butoxycarbonyl)-D-phenylalanine &gt
  • D-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
  • BC-D-phenylalanine
  • (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoicaci
  • BOC-D-Phenylalanine USP/EP/BP
  • Boc-D-Phe-OH (Bortezomib Impurity)
  • TIANFU-CHEM 18942-49-9 BOC-D-Phenylalanine
  • (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylp
  • Bortezomib impurity 99
  • 18942-49-9
  • 156-2-70
  • Specialty Synthesis
  • Phenylalanine
  • Peptide Synthesis
  • Amino Acid Derivatives
  • Phenylalanine [Phe, F]
  • Boc-Amino Acids and Derivative
  • Amino Acids (N-Protected)
  • Biochemistry
  • Boc-Amino Acids
  • Boc-Amino acid series
  • Amino Acids