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Neocuproine

Product Name
Neocuproine
CAS No.
484-11-7
Chemical Name
Neocuproine
Synonyms
2,9-DIMETHYL-1,10-PHENANTHROLINE;DMPHEN;Mephen;2,9-Dimethylphenanthroline;2,9-Dimethyl-o-phenanthroline;VUF 7738;NEOCUPROINE;Cuproin,neo;Neo-Cuproin;2,9-DimethyL
CBNumber
CB0429520
Molecular Formula
C14H12N2
Formula Weight
208.26
MOL File
484-11-7.mol
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Neocuproine Property

Melting point:
159-164 °C
Boiling point:
337.46°C (rough estimate)
Density 
1.1345 (rough estimate)
refractive index 
1.6152 (estimate)
RTECS 
SF8380000
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
methanol: 0.1 g/mL, clear
form 
crystalline
pka
6.01±0.30(Predicted)
color 
white to beige
Water Solubility 
slightly soluble
Sensitive 
Light Sensitive
Merck 
6449
InChIKey
IYRGXJIJGHOCFS-UHFFFAOYSA-N
CAS DataBase Reference
484-11-7(CAS DataBase Reference)
NIST Chemistry Reference
1,10-Phenanthroline, 2,9-dimethyl-(484-11-7)
EPA Substance Registry System
1,10-Phenanthroline, 2,9-dimethyl- (484-11-7)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22-22
Safety Statements 
26-36/37/39-36-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N1501
Product name
Neocuproine
Purity
≥98%
Packaging
1g
Price
$36.1
Updated
2024/03/01
Sigma-Aldrich
Product number
N1501
Product name
Neocuproine
Purity
≥98%
Packaging
5g
Price
$108
Updated
2024/03/01
Sigma-Aldrich
Product number
1.02968
Product name
Neocuproine
Purity
GR for analysis
Packaging
5G
Price
$341
Updated
2024/03/01
Alfa Aesar
Product number
J63698
Product name
2,9-Dimethyl-1,10-phenanthroline, 98%
Packaging
5g
Price
$69.4
Updated
2024/03/01
Alfa Aesar
Product number
J63698
Product name
2,9-Dimethyl-1,10-phenanthroline, 98%
Packaging
25g
Price
$266
Updated
2024/03/01
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Neocuproine Chemical Properties,Usage,Production

Chemical Properties

OFF-WHITE TO VERY PALE YELLOW CRYSTALLINE POWDER

Uses

Due to the steric hindrance of the methyl groups attached to the carbon atoms adjacent to the nitrogen donor atoms of phenanthroline, the reagent does not give the low spin vivid red complex characteristic of phenanthroline derivatives with iron(II). However, in the presence of reducing agents it reacts with copper to give a copper(I) complex of composition MA2 and of tetrahedral symmetry. This chelate is insoluble in water and can be extracted by chloroform in which the absorption maximum of the complex appears at 457 nm. In this way the concentration of the complex can be measured. The method is suitable for the determination of copper in iron, manganese and vanadium ores even in the presence of aluminium, germanium, titanium and silicon.
Neocuproine is today considered one of the most selective reagents. Unfortunately, it is rather expensive. 2,3-bis-(2-pyridyl)quinoxaline, prepared by Belcher et al. by condensation of o-diketone, 2,2'-dipyridyl and 0-phenylenediamine(44) contains the functional grouping characteristic of cuproine; it is quite suitable for the determination of copper and it is cheap. Starting with various substituted o-phenylene-diamines Belcher synthesized 25 different quinoxaline derivatives, of which 2,3-bis-[2-(-methyl)-pyridyl)]quinoxaline proved to be identical with neocuproine as regards analytical selectivity. Besides copper, titanium(III) is the only metal ion which gives a colour reaction with the reagent. However, the coloured titanium(III) complex is formed only at lower pH and hence it does not interfere with the determination of copper. The copper complex of the reagent can be extracted quantitatively with isopentyl alcohol usually as a perchlorate ion pair.

Uses

Neocuproine is a phenanthroline based metal ion chelating agent.

Definition

ChEBI: A member of the class of phenanthrolines that is 1,10-phenanthroline bearing two methyl substituents at positions 2 and 9.

Purification Methods

Purifiy it as the hemihydrate by crystallisation from water and as the anhydrous base from *benzene. [Beilstein 23/8 V 527.]

Neocuproine Preparation Products And Raw materials

Raw materials

Preparation Products

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Neocuproine Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82
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View Lastest Price from Neocuproine manufacturers

Shanghai UCHEM Inc.
Product
2,9-Dimethyl-1,10-phenanthroline 484-11-7
Price
US $52.00-500.00/g
Min. Order
1g
Purity
0.98
Supply Ability
10kg
Release date
2023-10-17
Hebei Chuanghai Biotechnology Co,.LTD
Product
Neocuproine 484-11-7
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19
Honest Joy Holdings Limited
Product
Neocuproine 484-11-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98.6%
Supply Ability
100 tons
Release date
2022-02-18

484-11-7, NeocuproineRelated Search:


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  • 2,9-DIMETHYL-1,10-PHENANTHROLINE REAGENT (ACS)
  • 1,10-Phenanthroline, 2,9-dimethyl-
  • 2,9-DIMETHYL-1,10-PHENANTHROLINE, REAGENT (ACS)2,9-DIMETHYL-1,10-PHENANTHROLINE, REAGENT (ACS)2,9-DIMETHYL-1,10-PHENANTHROLINE, REAGENT (ACS)2,9-DIMETHYL-1,10-PHENANTHROLINE, REAGENT (ACS)
  • Neocuproine, 98.5%, reagent grade
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  • 484-11-7
  • C14H12N212H2O
  • CH32C12H6N2
  • C14H12N205H2O
  • Chelating Reagents
  • Phenanthrolines
  • Analytical Reagents
  • Analytical Chromatography Product Catalog
  • General Use
  • Puriss p.a.
  • Analytical Chemistry