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2-Isopropyl-4-(methylaminomethyl)thiazole

Product Name
2-Isopropyl-4-(methylaminomethyl)thiazole
CAS No.
154212-60-9
Chemical Name
2-Isopropyl-4-(methylaminomethyl)thiazole
Synonyms
2-ISOPROPYL-4-(METHYLAMINOMETHYL)THIAZOLE;N-Methyl-2-isopropyl-4-thiazoleMethylaMine;2-isopropyl-4-(N-methyl)aminomethylthiazole;(2-isopropylthiazol-4-yl)-N-methylmethanamine;1-(2-Isopropyl-4-thiazolyl)-N-methylmethanamine;1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine;N-methyl-1-(2-propan-2-yl-4-thiazolyl)methanamine;4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-;N-methyl-(2-isopropyl-1,3-thiazol-4-yl)methylamine;1-(2-isopropyl-1,3-thiazol-4-yl)-N-MethylMethanaMine
CBNumber
CB0434553
Molecular Formula
C8H14N2S
Formula Weight
170.28
MOL File
154212-60-9.mol
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2-Isopropyl-4-(methylaminomethyl)thiazole Property

Boiling point:
230.9±15.0 °C(Predicted)
Density 
1.039±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
pka
8.06±0.10(Predicted)
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C8H14N2S/c1-6(2)8-10-7(4-9-3)5-11-8/h5-6,9H,4H2,1-3H3
InChIKey
HWSFABGWAXURNG-UHFFFAOYSA-N
SMILES
S1C=C(CNC)N=C1C(C)C
CAS DataBase Reference
154212-60-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
21/22-38-41-51/53
Safety Statements 
26-36/37/39-61
HS Code 
2934100090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I874655
Product name
2-Isopropyl-4-(methylaminomethyl)thiazole
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
I874655
Product name
2-Isopropyl-4-(methylaminomethyl)thiazole
Packaging
500mg
Price
$155
Updated
2021/12/16
TRC
Product number
I874655
Product name
2-Isopropyl-4-(methylaminomethyl)thiazole
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
7H31-1-0E
Product name
2-Isopropyl-4-(methylaminomethyl)thiazole
Purity
95%
Packaging
1g
Price
$328
Updated
2021/12/16
Matrix Scientific
Product number
118951
Product name
2-Isopropyl-4-(methylaminomethyl)thiazole
Purity
95+%
Packaging
5g
Price
$480
Updated
2021/12/16
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2-Isopropyl-4-(methylaminomethyl)thiazole Chemical Properties,Usage,Production

Synthesis

40516-57-2

74-89-5

154212-60-9

To a 250 mL three-necked flask was added 4-(chloromethyl)-2-isopropylthiazole (9 g, 0.05 mol) and 40% aqueous methylamine solution (100 mL). The reaction mixture was heated to 50-60 °C and the reaction was stirred at this temperature overnight. After the reaction was completed, the mixture was cooled to room temperature. Dichloromethane (100 mL) and isopropanol (30 mL) were added to the reaction mixture, which was stirred thoroughly and left to stratify. The aqueous phase was separated and the aqueous phase was extracted with dichloromethane 3 times. All organic phases were combined and dried with anhydrous sodium sulfate. The dried organic phase was filtered and the filtrate was concentrated under reduced pressure to remove the solvent. The crude product was purified by column chromatography (silica gel, appropriate eluent) to afford 2-isopropyl-4-(methylaminomethyl)thiazole (6.5 g, 74% yield) as a colorless liquid.

References

[1] Patent: CN104557763, 2017, B. Location in patent: Paragraph 0026; 0034; 0035; 0036; 0046; 0056; 0064-0066
[2] Patent: WO2006/90270, 2006, A1. Location in patent: Page/Page column 8-9

2-Isopropyl-4-(methylaminomethyl)thiazole Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Isopropyl-4-(methylaminomethyl)thiazole Suppliers

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View Lastest Price from 2-Isopropyl-4-(methylaminomethyl)thiazole manufacturers

R&D Scientific Inc.
Product
2-Isopropyl-4-(methylaminomethyl)thiazole 154212-60-9
Price
US $800.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-02-21
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Isopropyl-4-(methylaminomethyl)thiazole 154212-60-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Isopropyl-4-(methylaminomethyl)thiazole 154212-60-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

154212-60-9, 2-Isopropyl-4-(methylaminomethyl)thiazoleRelated Search:

METSULFURON METHYL N,N-Dimethyl-1,4-phenylenediamine 3-Methyl-2-butanone Bensulfuron methyl Methyl salicylate 2-Aminothiazole-4-acetic acid 4-Methylthiazole Thiazole ISOPROPYL LAURATE Methylparaben 2-Methyl-4-isothiazolin-3-one Methyl acetate Kresoxim-methyl Isopropyl alcohol 5-Amino-2-methylpyridine Thiophanate-methyl Tris(hydroxymethyl)aminomethane THIAZOLE ORANGE

  • 2-ISOPROPYL-4-(METHYLAMINOMETHYL)THIAZOLE
  • 1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine
  • 2-isopropyl-1,3-thiazol-4-methylmethanamine hydrochloride
  • 2-Isopropyl-4-(Methylaminomethyl)Thiazole(IntermediateOfRitonavir)
  • N-methyl-(2-isopropyl-1,3-thiazol-4-yl)methylamine
  • 4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-
  • 1-(2-isopropyl-1,3-thiazol-4-yl)-N-methylmethanamine(SALTDATA: 2HCl 0.4H2O 0.01S8)
  • 1-(2-isopropyl-1,3-thiazol-4-yl)-N-MethylMethanaMine
  • [(2-Isopropyl-1,3-thiazol-4-yl)Methyl]MethylaMine 2HCl
  • N-Methyl-2-isopropyl-4-thiazoleMethylaMine
  • 2-isopropyl-4-(N-methyl)aminomethylthiazole
  • N-methyl-1-(2-propan-2-yl-1,3-thiazol-4-yl)methanamine
  • 2-Isopropil-4-(Methylaminomethyl) Thiazole(Ritonavir Intermediate)
  • (2-isopropylthiazol-4-yl)-N-methylmethanamine
  • 1-(2-Isopropyl-4-thiazolyl)-N-methylmethanamine
  • N-methyl-1-(2-propan-2-yl-4-thiazolyl)methanamine
  • N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amine hydrochloride
  • 2-Isopropyl-4-(Methyl Amino Methyl) Thiazole (MTV-II)
  • 154212-60-9
  • C8H14N2S