ChemicalBook > CAS DataBase List > 6-BROMO-2-QUINAZOLINAMINE

6-BROMO-2-QUINAZOLINAMINE

Product Name
6-BROMO-2-QUINAZOLINAMINE
CAS No.
190273-89-3
Chemical Name
6-BROMO-2-QUINAZOLINAMINE
Synonyms
6-BROMOQUINAZOLIN-2-AMINE;6-BROMO-2-QUINAZOLINAMINE;2-AMINO-6-BROMOQUINAZOLINE;6-Bromo-2-amino-quinazoline;6-Bromoquinazolin-2-ylamine;2-Quinazolinamine, 6-bromo-
CBNumber
CB0442527
Molecular Formula
C8H6BrN3
Formula Weight
224.06
MOL File
190273-89-3.mol
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6-BROMO-2-QUINAZOLINAMINE Property

Boiling point:
425.3±37.0 °C(Predicted)
Density 
1.744±0.06 g/cm3(Predicted)
storage temp. 
Room temperature.
pka
4.94±0.26(Predicted)
Appearance
Light yellow to brown Solid
InChI
InChI=1S/C8H6BrN3/c9-6-1-2-7-5(3-6)4-11-8(10)12-7/h1-4H,(H2,10,11,12)
InChIKey
IJXKEDDKGGBSBX-UHFFFAOYSA-N
SMILES
N1=C2C(C=C(Br)C=C2)=CN=C1N
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A595090
Product name
2-Amino-6-bromoquinazoline
Packaging
500mg
Price
$90
Updated
2021/12/16
TRC
Product number
A595090
Product name
2-Amino-6-bromoquinazoline
Packaging
250mg
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB42042
Product name
6-Bromo-2-quinazolinamine
Packaging
100mg
Price
$60
Updated
2021/12/16
BroadPharm
Product number
BP-20077
Product name
6-bromoquinazolin-2-amine
Purity
95%
Packaging
250mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB42042
Product name
6-Bromo-2-quinazolinamine
Packaging
1g
Price
$250
Updated
2021/12/16
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6-BROMO-2-QUINAZOLINAMINE Chemical Properties,Usage,Production

Synthesis

593-85-1

93777-26-5

190273-89-3

5-Bromo-2-fluorobenzaldehyde (10 g, 49.2 mmol) and guanidine carbonate (13.3 g, 74 mmol) were dissolved in N,N-dimethylacetamide (50 mL). The reaction mixture was heated to reflux temperature with continuous stirring for 5 hours. Upon completion of the reaction, it was cooled to room temperature, water (120 mL) was added and stirring was continued for 2 hours at room temperature. The resulting 6-bromo-2-quinazolinamine was collected by filtration and subsequently dried under vacuum to give the final product (5.0 g, 60% yield).

References

[1] Patent: WO2017/46739, 2017, A1. Location in patent: Page/Page column 49
[2] European Journal of Medicinal Chemistry, 2017, vol. 141, p. 506 - 518
[3] Journal of Organic Chemistry, 2006, vol. 71, # 10, p. 3959 - 3962
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 19, p. 5671 - 5686
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 11, p. 3065 - 3068

6-BROMO-2-QUINAZOLINAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-2-QUINAZOLINAMINE Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from 6-BROMO-2-QUINAZOLINAMINE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
6-BROMO-2-QUINAZOLINAMINE 190273-89-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
2000
Release date
2025-09-04
Shaanxi Dideu New Materials Co. Ltd
Product
6-BROMO-2-QUINAZOLINAMINE 190273-89-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-11
Henan Fengda Chemical Co., Ltd
Product
6-Bromoquinazolin-2-amine 190273-89-3
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30