ChemicalBook > CAS DataBase List > n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride

n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride

Product Name
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
CAS No.
7084-11-9
Chemical Name
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
Synonyms
EDCI;EDCL;EDAC;EDCI HCL;1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE;EDC HYDROCHLORIDE;EPCI;3-(3-DIMETHYLAMINOPROPYL)-1-ETHYLCARBODIIMIDE HYDROCHLORIDE;WSC HCL;1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE HCL
CBNumber
CB0443054
Molecular Formula
C8H18ClN3
Formula Weight
191.7
MOL File
7084-11-9.mol
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n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Property

Melting point:
110-115 °C(lit.)
storage temp. 
Inert atmosphere,Room Temperature
CAS DataBase Reference
7084-11-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-36/37/39
WGK Germany 
3
RTECS 
FF2200000
3-10-21
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FD158026
Product name
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
Packaging
25g
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD158026
Product name
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
Packaging
50g
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD158026
Product name
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
Packaging
100g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD158026
Product name
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
Packaging
250g
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD158026
Product name
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
Packaging
500g
Price
$475
Updated
2021/12/16
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n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Chemical Properties,Usage,Production

Description

Among the carbodiimides available, n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide (EDC) hydrochlorideis commonly used because it is available as an HCl salt, is easy to handle, and the urea by-product, N-(3-dimethylaminopropyl)-N' -ethylurea (EDU), is soluble in water and can easily be removed[1].

Uses

N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide (EDC) is a carbodiimide coupling reagent commonly used for the preparation of amides from carboxylic acids and amines[1].

Toxicology

N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) was considered to be potentially genotoxic; however, later studies determined that EDC is not genotoxic. 4 in vitro Ames bacterial mutagenicity tests indicated EDC is genotoxic, but the reagent is not genotoxic in vivo when administered to rats orally. When administered orally, EDC is hydrolyzed to EDU, which is not genotoxic[1].

References

[1] Kai Cao, Samuel J. Bonacorsi Jr, John A. Brailsford. “Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea.” Journal of labelled compounds & radiopharmaceuticals 63 13 (2020): 526–530.

n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Preparation Products And Raw materials

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Preparation Products

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View Lastest Price from n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE 7084-11-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Hebei Yanxi Chemical Co., Ltd.
Product
N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE 7084-11-9
Price
US $30.00-3.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-20
Henan Bao Enluo International TradeCo.,LTD
Product
N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE 7084-11-9
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500t/month
Release date
2023-07-26

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