n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
- Product Name
- n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
- CAS No.
- 7084-11-9
- Chemical Name
- n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
- Synonyms
- EDCI;EDCL;EDAC;EDCI HCL;1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE;EDC HYDROCHLORIDE;EPCI;3-(3-DIMETHYLAMINOPROPYL)-1-ETHYLCARBODIIMIDE HYDROCHLORIDE;WSC HCL;1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE HCL
- CBNumber
- CB0443054
- Molecular Formula
- C8H18ClN3
- Formula Weight
- 191.7
- MOL File
- 7084-11-9.mol
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Property
- Melting point:
- 110-115 °C(lit.)
- storage temp.
- Inert atmosphere,Room Temperature
- CAS DataBase Reference
- 7084-11-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 37/38-41
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- RTECS
- FF2200000
- F
- 3-10-21
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FD158026
- Product name
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- Packaging
- 25g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FD158026
- Product name
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- Packaging
- 50g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FD158026
- Product name
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- Packaging
- 100g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FD158026
- Product name
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- Packaging
- 250g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- FD158026
- Product name
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- Packaging
- 500g
- Price
- $475
- Updated
- 2021/12/16
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Chemical Properties,Usage,Production
Description
Among the carbodiimides available, n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide (EDC) hydrochlorideis commonly used because it is available as an HCl salt, is easy to handle, and the urea by-product, N-(3-dimethylaminopropyl)-N' -ethylurea (EDU), is soluble in water and can easily be removed[1].
Uses
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide (EDC) is a carbodiimide coupling reagent commonly used for the preparation of amides from carboxylic acids and amines[1].
Toxicology
N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) was considered to be potentially genotoxic; however, later studies determined that EDC is not genotoxic. 4 in vitro Ames bacterial mutagenicity tests indicated EDC is genotoxic, but the reagent is not genotoxic in vivo when administered to rats orally. When administered orally, EDC is hydrolyzed to EDU, which is not genotoxic[1].
References
[1] Kai Cao, Samuel J. Bonacorsi Jr, John A. Brailsford. “Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea.” Journal of labelled compounds & radiopharmaceuticals 63 13 (2020): 526–530.
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Suppliers
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- Switzerland
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View Lastest Price from n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride manufacturers
- Product
- N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE 7084-11-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25
- Product
- N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE 7084-11-9
- Price
- US $30.00-3.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-20
- Product
- N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE 7084-11-9
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500t/month
- Release date
- 2023-07-26