2-HYDROXY-5-IODO-BENZALDEHYDE
- Product Name
- 2-HYDROXY-5-IODO-BENZALDEHYDE
- CAS No.
- 1761-62-2
- Chemical Name
- 2-HYDROXY-5-IODO-BENZALDEHYDE
- Synonyms
- AKOS B028970;SALOR-INT L497630-1EA;5-IODOSALICYLALDEHYDE;5-iodosalicyclaldehyde;Iodosalicylaldehyde,5-;LABOTEST-BB LT00137782;5-Iodosalicylaldehyde 97%;5-IODO-2-HYDROXYBENZALDEHYDE;2-HYDROXY-5-IODO-BENZALDEHYDE;Benzaldehyde, 2-hydroxy-5-iodo-
- CBNumber
- CB0445760
- Molecular Formula
- C7H5IO2
- Formula Weight
- 248.02
- MOL File
- 1761-62-2.mol
2-HYDROXY-5-IODO-BENZALDEHYDE Property
- Melting point:
- 98-100 °C (lit.)
- Boiling point:
- 282.0±30.0 °C(Predicted)
- Density
- 30 g/mL at 25 °C(lit.)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 7.56±0.18(Predicted)
- Appearance
- Light brown to yellow Solid
- Sensitive
- Light Sensitive
- InChI
- InChI=1S/C7H5IO2/c8-6-1-2-7(10)5(3-6)4-9/h1-4,10H
- InChIKey
- PDFVIWFKGYODKD-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC(I)=CC=C1O
- CAS DataBase Reference
- 1761-62-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 524328
- Product name
- 5-Iodosalicylaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $76
- Updated
- 2025/07/31
- Product number
- I1175
- Product name
- 2-Hydroxy-5-iodobenzaldehyde
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $30
- Updated
- 2025/07/31
- Product number
- I1175
- Product name
- 2-Hydroxy-5-iodobenzaldehyde
- Purity
- min. 95.0 %
- Packaging
- 5G
- Price
- $89
- Updated
- 2025/07/31
- Product number
- H953603
- Product name
- 2-Hydroxy-5-iodobenzaldehyde
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 064568
- Product name
- 2-Hydroxy-5-iodobenzaldehyde
- Packaging
- 5g
- Price
- $145
- Updated
- 2021/12/16
2-HYDROXY-5-IODO-BENZALDEHYDE Chemical Properties,Usage,Production
Uses
5-Iodosalicylaldehyde may be used to synthesize:
- 5-formylsalicylaldehyde
- 5-ortho-carboranylsalicylaldehyde
- new salen (N,N′-Bis(salicylidene)ethylenediamine) ligands that are tethered to a p-acylthio(phenylacetylene)n linker
General Description
5-Iodosalicylaldehyde is a salicylaldehyde derivative.
Synthesis
90-02-8
1761-62-2
General procedure for the synthesis of 5-iodosalicylaldehyde from salicylaldehyde: To a stirred solution of salicylaldehyde (1 mmol) in dichloromethane (CH2Cl2) or 1,2-dichloroethane ((CH2Cl)2) (0.1 M) was added triphenylphosphorane bis(trifluoromethylsulfonyl)imide (Ph3PAuNTf2) (0.025 mmol, 19 mg; if toluene-ligated Ph3PAuNTf2 complex, the ratio was 2:1), followed by the addition of N-iodosuccinimide (NIS) (1.1 mmol, 248 mg). The reaction mixture was stirred at room temperature or reacted under reflux conditions until complete conversion of salicylaldehyde was confirmed by thin layer chromatography (TLC) monitoring. Upon completion of the reaction, the solvent was evaporated under reduced pressure and the resulting crude product was purified by fast column chromatography using different ratios of hexane and ethyl acetate (EtOAc) as eluents to finally obtain purified 5-iodosalicylaldehyde.
References
[1] Journal of Organic Chemistry, 2015, vol. 80, # 9, p. 4306 - 4312
[2] Synlett, 2014, vol. 25, # 3, p. 399 - 402
[3] European Journal of Organic Chemistry, 2016, vol. 2016, # 12, p. 2177 - 2186
[4] Angewandte Chemie - International Edition, 2007, vol. 46, # 4, p. 572 - 575
[5] Chemistry - A European Journal, 2013, vol. 19, # 7, p. 2442 - 2449
2-HYDROXY-5-IODO-BENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-HYDROXY-5-IODO-BENZALDEHYDE Suppliers
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- Switzerland
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View Lastest Price from 2-HYDROXY-5-IODO-BENZALDEHYDE manufacturers
- Product
- 2-HYDROXY-5-IODO-BENZALDEHYDE 1761-62-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-HYDROXY-5-IODO-BENZALDEHYDE 1761-62-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-11