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ChemicalBook > CAS DataBase List > 4-(Trifluoromethoxy)benzyl bromide

4-(Trifluoromethoxy)benzyl bromide

Uses
Product Name
4-(Trifluoromethoxy)benzyl bromide
CAS No.
50824-05-0
Chemical Name
4-(Trifluoromethoxy)benzyl bromide
Synonyms
1-(BROMOMETHYL)-4-(TRIFLUOROMETHOXY)BENZENE;TIMTEC-BB SBB006578;Pretomanid Impurity 4;4-(Trifluoromethoxy)benzyl;TrifluoroMethoxy BroMobenzyl;4-trifluoromethoxybromobenzyl;P-TritluromethoxybenzylBromide;4-trifluoromethoxylbenzylbromide;4-(TRIFLUOROMETHOXY)BENZYL BROMIDE;4-(Trifluoromethyloxy）benzylbromide
CBNumber
CB0452065
Molecular Formula
C8H6BrF3O
Formula Weight
255.03
MOL File
50824-05-0.mol
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4-(Trifluoromethoxy)benzyl bromide Property

Melting point:
22-24°C
Boiling point:
82-84 °C10 mm Hg(lit.)
Density 
1.594 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.48(lit.)
Flash point:
202 °F
storage temp. 
Refrigerated.
solubility 
soluble in Chloroform, Methanol
form 
Liquid or Low Melting Solid
Specific Gravity
1.594
color 
Clear faintly yellow
Sensitive 
Lachrymatory
BRN 
2521451
CAS DataBase Reference
50824-05-0(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-27-28-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
Hazard Note 
Corrosive/Lachrymatory
HazardClass 
8
PackingGroup 
III
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
370622
Product name
4-(Trifluoromethoxy)benzyl bromide
Purity
97%
Packaging
1g
Price
$33.72
Updated
2024/03/01
Sigma-Aldrich
Product number
370622
Product name
4-(Trifluoromethoxy)benzyl bromide
Purity
97%
Packaging
5g
Price
$134
Updated
2024/03/01
TCI Chemical
Product number
T1781
Product name
4-(Trifluoromethoxy)benzyl Bromide
Purity
>98.0%(GC)
Packaging
1g
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
T1781
Product name
4-(Trifluoromethoxy)benzyl Bromide
Purity
>98.0%(GC)
Packaging
5g
Price
$102
Updated
2024/03/01
Alfa Aesar
Product number
A18335
Product name
4-(Trifluoromethoxy)benzyl bromide, 97%
Packaging
5g
Price
$108.65
Updated
2024/03/01
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4-(Trifluoromethoxy)benzyl bromide Chemical Properties,Usage,Production

Uses

4-Trifluoromethoxybenzyl Bromide is a useful synthetic intermediate. It is used to prepare (nitro)[(trifluoromethoxy)benzyloxy]dihydroimidazo[2,1-b][1,3]oxazines with antitubercular activities. It is also used to synthesize tetrahydronaphthalenols with anti-allergic activities.

Chemical Properties

Colorless to light yellow liqui

Uses

4-(Trifluoromethoxy)benzyl bromide may be used in the synthesis of bioreductive drug, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).

General Description

Polymerizations of 4-(trifluoromethoxy)benzyl bromide, via Friedel-Crafts polymerization using aluminum chloride as a catalyst has been reported.

4-(Trifluoromethoxy)benzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

4-(Trifluoromethyl)phenylacetic acid
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View Lastest Price from 4-(Trifluoromethoxy)benzyl bromide manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-(Trifluoromethoxy)benzyl bromide 50824-05-0
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
Shaanxi Dideu Medichem Co. Ltd
Product
4-(Trifluoromethoxy)benzyl bromide 50824-05-0
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%
Supply Ability
2000tons
Release date
2020-01-16
Hebei Mojin Biotechnology Co., Ltd
Product
4-(Trifluoromethoxy)benzyl bromide 50824-05-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-13

50824-05-0, 4-(Trifluoromethoxy)benzyl bromideRelated Search:

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  • C8H6BrOF3
  • BENZYL HALIDE
  • Ethers
  • Oxygen Compounds
  • Organic Building Blocks
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  • Aromatic Halides (substituted)
  • Miscellaneous
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  • Organic Building Blocks
  • Oxygen Compounds
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