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MMP INHIBITOR I

Product Name
MMP INHIBITOR I
CAS No.
124168-73-6
Chemical Name
MMP INHIBITOR I
Synonyms
FN-439;MMP INHIBITOR I;MMP INHIBITOR 1;METALLOPROTEASE INHIBITOR 1;4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;H-4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;MATRIX METALLOPROTEINASE INHIBITOR I;P-aminobenzoyl-gly-pro-D-leu-D-ala*hydroxamic aci;4-aminobenzoyl-gly-pro-d-leu-d-ala hydroxamic acid;P-AMINOBENZOYL-GLY-PRO-D-LEU-D-ALA HYDROXAMIC ACID
CBNumber
CB0456098
Molecular Formula
C23H34N6O6
Formula Weight
490.55
MOL File
124168-73-6.mol
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MMP INHIBITOR I Property

Density 
1.288±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: 1 mg/mL
pka
9.34±0.40(Predicted)
form 
solid
color 
white
Water Solubility 
water: 1mg/mL
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
444250
Product name
MMP Inhibitor I
Purity
The MMP Inhibitor I controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Packaging
10MG
Price
$214
Updated
2025/07/31
Sigma-Aldrich
Product number
A4336
Product name
4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid
Purity
≥95% (HPLC)
Packaging
5mg
Price
$278
Updated
2023/06/20
Chem-Impex
Product number
32933
Product name
4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
Packaging
5MG
Price
$72
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA111048
Product name
4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
Packaging
5mg
Price
$118
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA111048
Product name
4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
Packaging
10mg
Price
$205
Updated
2021/12/16
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MMP INHIBITOR I Chemical Properties,Usage,Production

Uses

FN-439 is a selective collagenase-1 inhibitor. FN-439 inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 can be used for the research of cancer and inflammation[1][2].

Biological Activity

Collagenase Inhibitor

in vivo

FN-439 significantly decreases neutrophils and macrophages, shows extensive bone formation and active cementogenesis in the periapical region when has a combination with ofloxaci[2].

References

[1] U Benbow, et al. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clin Exp Metastasis. 1999 May;17(3):231-8. DOI:10.1023/a:1006639214618
[2] H Anan, et al. Effects of a combination of an antibacterial agent (ofloxacin) and a collagenase inhibitor (FN-439) on the healing of rat periapical lesions. J Endod. 1996 Dec;22(12):668-73. DOI:10.1016/S0099-2399(96)80061-6

MMP INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

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MMP INHIBITOR I Suppliers

China 45 Germany 1 Japan 1 Switzerland 1 United Kingdom 2 United States 17 Global 67
VDM Biochemicals
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TargetMol Chemicals Inc.
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EMD Biosciences, Inc.
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MP Biomedicals, Inc.
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Chem-Impex International, Inc.
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Kamiya Biomedical Company
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124168-73-6, MMP INHIBITOR IRelated Search:

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  • P-aminobenzoyl-gly-pro-D-leu-D-ala*hydroxamic aci
  • 4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH
  • METALLOPROTEASE INHIBITOR 1
  • MATRIX METALLOPROTEINASE INHIBITOR I
  • 4-aminobenzoyl-gly-pro-d-leu-d-ala hydroxamic acid
  • D-AlaninaMide, N-(4-aMinobenzoyl)glycyl-L-prolyl-D-leucyl-N-hydroxy-
  • 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
  • H-4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH
  • FN-439
  • MMP INHIBITOR 1
  • MMP INHIBITOR I
  • P-AMINOBENZOYL-GLY-PRO-D-LEU-D-ALA HYDROXAMIC ACID
  • 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid >=95% (HPLC)
  • 4-Aminobenzoyl-Gly-Pro-<sc>D</sc>-Leu-<sc>D</sc>-Ala hydroxamic acid
  • 124168-73-6
  • C23H34N6O6
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Extracellular Matrix
  • Cytoskeleton and Extracellular Matrix
  • Metalloproteinase Inhibitors
  • Inhibitor of human matrix metalloproteinases.