ChemicalBook > CAS DataBase List > (-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE

(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE

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Product Name: (-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE
CAS No.: 147253-67-6
Chemical Name: (-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE
Synonyms: an-1-yL;(R,R)-ME-DUPHOS;(R,R)-METHYL-DUPHOS;()-1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene;(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzen;1,2-Bis[(2R,5R)-2,5-dimethyl-1-phospholanyl]benzene;(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE;1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)benzene;(-)-1,2-bis-((2R,5R)-2,5-Dimethylphospholano)benzene;(-) -1,2-bis ((2R, 5R) -2,5-dimethylphosphorus) benzene
CBNumber: CB0456508
Molecular Formula: C18H28P2
Formula Weight: 306.36
MOL File: 147253-67-6.mol

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(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE Property

Melting point:: 66-76 °C
alpha: -476° (c 1, hexane)
Boiling point:: 415.0±15.0 °C(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: crystal
color: white
optical activity: [α]20/D -420±15°, c = 0.5 in methylene chloride
Water Solubility: Insoluble in water.
Sensitive: Air Sensitive
BRN: 4810602
CAS DataBase Reference: 147253-67-6

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-23
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 665258
Product name: (?)-1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene
Purity: kanata purity
Packaging: 100mg
Price: $78.5
Updated: 2023/06/20

TCI Chemical

Product number: B2436
Product name: 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene
Packaging: 100MG
Price: $97
Updated: 2025/07/31

TCI Chemical

Product number: B2436
Product name: 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene
Packaging: 500MG
Price: $401
Updated: 2025/07/31

Strem Chemicals

Product number: 15-0096
Product name: (-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene, 98+% (R,R)-Me-DUPHOS
Packaging: 100mg
Price: $60
Updated: 2024/03/01

Strem Chemicals

Product number: 15-0096
Product name: (-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene, 98+% (R,R)-Me-DUPHOS
Packaging: 500mg
Price: $258
Updated: 2024/03/01

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(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE Chemical Properties,Usage,Production

Reactions

The DUPHOS family of catalysts is highly efficient for the asymmetric hydrogenation of various substituted cetamidoacrylates and enol acetates yielding products of high enantiomeric excesses.
Efficient ligand for the asymmetric hydrogenation of imines, enamines, and enamides.
Asymmetric hydrogenation of vinyl alcohols.
Catalyst used for the asymmetric hydrogenation of enol phosphonates.
Asymmetric hydrogenation of allylic alcohols.
Ligand for the catalytic asymmetric [4+1] cycloaddition of vinylallenes with CO.
Ligand for the Rh-catalyzed asymmetric enyne cycloisomerization.
Catalytic enantioselective addition of dialkylzinc to N-Diphenylphosphinoylimines.

Uses

1,2-Bis[(2R,5R)-2,5-dimethyl-1-phospholanyl]benzene is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It is used as highly efficient privileged ligands.

(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE manufacturers

Career Henan Chemical Co

Product: (-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE 147253-67-6
Price: US $7.00/KG
Min. Order: 0.1KG
Purity: 98%
Supply Ability: 1KG; 10KG; 50KG; 100KG and more
Release date: 2024-10-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: ()-1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene 147253-67-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

147253-67-6, (-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENERelated Search:

(+)-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene,98+%(S,S)-Me-DUPHOS,(+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE (-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE (3R,6R)-3,6-OCTANEDIOL (-)-1,2-BIS((2R,5R)-2,5-DIPHENYLPHOSPHOLANO)ETHANE (R)-5-fluoro-3-methylisobenzofuran-1(3H)-one (+)-1,2-BIS[(2S,5S)-2,5-DIETHYLPHOSPHOLANO]BENZENE (S)-5-fluoro-3-methylisobenzofuran-1(3H)-one (-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE(CYCLOOCTADIENE)RHODIUM(L)TETRAFLUOROBORATE (-)-1,2-Bis[(2R,5R)-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) tetrafluoroborate (S,S)-I-PR-DUPHOS (-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE (-)-1,2(2R,5R)-2,5-(DIMETHYLPHOSPHOLANO)BENZENE(CYCLOOCTADIENE)RHODIUM(I)TRIFLUOROMETHANESULFONATE (+)-1,2-BIS((2S,5S)-2,5-DIMETHYLPHOSPHOLANO)BENZENE(CYCLOOCTADIENE)RHODIUM(I)TETRAFLUOROBORATE (-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE(CYCLOOCTADIENE)RHODIUM(I)TRIFLUOROMETHANESULFONATE (-)-1,2(2R,5R)-2,5-(DIMETHYLPHOSPHOLANO)BENZENE(CYCLOOCTADIENE)RHODIUM(I)TRIFLUOROMETHANESULFONATE 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene monooxide 1,2-Bis[(2S,5S)-2,5-dimethylphospholano]benzene monooxide (-)-1,2-BIS((2S,5S)-2,5-DI-I-PROPYLPHOSPHOLANO)BENZENE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE

(2R,2'R,5R,5'R)-2,2',5,5'-TETRAMETHYL-1,1'-(1,2-PHENYLENE)DIPHOSPHOLANE

(2R,2'R,5R,5'R)-2,2',5,5'-TETRAMETHYL-1,1'-(O-PHENYLENE)DIPHOSPHOLANE

(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE

(-)-1,2-BIS((2R,5R)-2,5-DIMETHYLPHOSPHOLANO)BENZENE, KANATA PURITY

(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(r,r)-me-duphos

(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene,98+%(R,R)-Me-DUPHOS

(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene, (R,R)-Me-DUPHOS,98+%

()-1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene,(2R,2’R,5R,5′R)-2,2′,5,5′-Tetramethyl-1,1′-(o-phenylene)diphospholane, (R,R)-Me-DUPHOS, (R,R)-Methyl-DUPHOS

1,2-Bis[(2R,5R)-2,5-diMethyl-1-phospholanyl]benzene, 97+%

(2R,5R,2'R,5'R)-1,1'-(1,2-Phenylene)bis(2,5-dimethylphospholane)

1,2-Bis[(2R,5R)-2,5-dimethyl-1-phospholanyl]benzene

(R,R)-ME-DUPHOS

(R,R)-METHYL-DUPHOS

()-1,2-Bis[(2R,5R)-2,5-diMethylphospholano]benzene,>=95.0%

1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)benzene

[2R-[1(2'R*,5'R*),2a,5b]]-1,1'-(1,2-phenylene)bis[2,5-dimethylphospholane]

(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene, min.97% (R,R)-Me-DUPHOS

Phospholane, 1,1'-(1,2-phenylene)bis[2,5-dimethyl-, (2R,2'R,5R,5'R)-

an-1-yL

()-1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene

(-)-1,2-bis-((2R,5R)-2,5-Dimethylphospholano)benzene

(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene (R,R)-Me-Duphos

(-) -1,2-bis ((2R, 5R) -2,5-dimethylphosphorus) benzene

()-1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene,≥95.0%

(?)-1,2-Bis[(2<i>R</i>,5<i>R</i>)-2,5-dimethylphospholano]benzene

(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzen

147253-67-6

C18H28P2

Asymmetric Synthesis

Chiral Catalysts, Ligands, and Reagents

Privileged Ligands

DuPhos/BPE

organophosphine ligand