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3-BROMO-4-CHLOROTOLUENE

Product Name
3-BROMO-4-CHLOROTOLUENE
CAS No.
57310-39-1
Chemical Name
3-BROMO-4-CHLOROTOLUENE
Synonyms
3-BROMO-4-CHLOROTOLUENE;4-Chluoro-3-bromotoluene;3 3-Bromo-4-Chloro Toluene;Benzene, 2-bromo-1-chloro-4-methyl-
CBNumber
CB0468671
Molecular Formula
C7H6BrCl
Formula Weight
205.48
MOL File
57310-39-1.mol
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3-BROMO-4-CHLOROTOLUENE Property

Boiling point:
112 °C
Density 
1,55 g/cm3
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol (Slightly)
form 
liquid
Specific Gravity
1.55
color 
Colourless
InChI
InChI=1S/C7H6BrCl/c1-5-2-3-7(9)6(8)4-5/h2-4H,1H3
InChIKey
UWXPTVKKHVOZLJ-UHFFFAOYSA-N
SMILES
C1(Cl)=CC=C(C)C=C1Br
CAS DataBase Reference
57310-39-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,N,Xn
Risk Statements 
22-51/53
Safety Statements 
61
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2903998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
B682495
Product name
2-Bromo-1-chloro-4-methyl-benzene
Packaging
5g
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB43405
Product name
3-Bromo-4-chlorotoluene
Packaging
50g
Price
$140.5
Updated
2021/12/16
Apolloscientific
Product number
OR6447
Product name
3-Bromo-4-chlorotoluene
Packaging
100g
Price
$189
Updated
2021/12/16
SynQuest Laboratories
Product number
1700-D-X8
Product name
3-Bromo-4-chlorotoluene
Packaging
100g
Price
$208
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB43405
Product name
3-Bromo-4-chlorotoluene
Packaging
100g
Price
$225
Updated
2021/12/16
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3-BROMO-4-CHLOROTOLUENE Chemical Properties,Usage,Production

Uses

2-Bromo-1-chloro-4-methyl-benzene is a useful synthetic intermediate. It can be used to synthesize N-heterocycle-fused phenanthridines via palladium-catalyzed tandem N-H/C-H arylation of aryl-N-heteroarenes with dihaloarenes. It can also be used to synthesize substituted fluorenes.

Synthesis

583-68-6

57310-39-1

General procedure for the synthesis of 4-chloro-3-bromotoluene from 2-bromo-4-methylaniline: tert-butyl nitrite (48 mmol, 6.34 mL) and anhydrous copper(II) chloride (60 mmol, 8.07 g) were mixed at 65 °C in anhydrous acetonitrile (100 mL). 2-Bromo-4-methylaniline (30 mmol) was slowly added under vigorous stirring for 30 min. Subsequently, the reaction mixture was continued to be stirred at 65 °C for 2 hours. After completion of the reaction, the mixture was cooled, poured into 20% hydrochloric acid (400 mL) and extracted with ether (3 x 120 mL). The organic phases were combined, washed with brine (100 mL), dried over anhydrous Na2SO4 and the solvent was subsequently evaporated. The crude product was purified by fast column chromatography.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 22, p. 5568 - 5572

3-BROMO-4-CHLOROTOLUENE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-4-CHLOROTOLUENE Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from 3-BROMO-4-CHLOROTOLUENE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
3-BROMO-4-CHLOROTOLUENE 57310-39-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
3-BROMO-4-CHLOROTOLUENE 57310-39-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 603
Release date
2019-09-01
Career Henan Chemical Co
Product
3-BROMO-4-CHLOROTOLUENE 57310-39-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 624
Release date
2019-09-01