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4-Bromo-3-nitrobenzotrifluoride

Product Name
4-Bromo-3-nitrobenzotrifluoride
CAS No.
349-03-1
Chemical Name
4-Bromo-3-nitrobenzotrifluoride
Synonyms
TIMTEC-BB SBB009903;3-nitro-4-broMotrifluorotoluol;4-BroMo-3-nitro-trifluoroMethyl;3-NITRO-4-BROMOBENZOTRIFLUORIDE;4-BROMO-3-NITROBENZOTRIFLUORIDE;2-Nitro-5-Bromotrifluorotoluene;4-Bromo-3-nitrobenzotrifluoride99%;4-Bromo-3-nitrobenzotrifluoride 99%;4-Bromo-3-nitrobenzotrifluoride,97%;4-Bromo-3-nitrobenzotrifluoride >
CBNumber
CB0486143
Molecular Formula
C7H3BrF3NO2
Formula Weight
270
MOL File
349-03-1.mol
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4-Bromo-3-nitrobenzotrifluoride Property

Boiling point:
90 °C (3 mmHg)
Density 
1.763 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.511(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Light yellow to Amber to Dark green
Specific Gravity
1.763
BRN 
2417762
CAS DataBase Reference
349-03-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22-36/38
Safety Statements 
36/37/39-26-37/39-36/37
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29049090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
365777
Product name
4-Bromo-3-nitrobenzotrifluoride
Purity
97%
Packaging
5g
Price
$46.1
Updated
2022/05/15
TCI Chemical
Product number
B3074
Product name
4-Bromo-3-nitrobenzotrifluoride
Purity
>98.0%(GC)
Packaging
5g
Price
$68
Updated
2025/07/31
TCI Chemical
Product number
B3074
Product name
4-Bromo-3-nitrobenzotrifluoride
Purity
>98.0%(GC)
Packaging
25g
Price
$198
Updated
2025/07/31
TRC
Product number
B697973
Product name
4-Bromo-3-nitrobenzotrifluoride
Packaging
5g
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB142694
Product name
4-Bromo-3-nitrobenzotrifluoride
Packaging
50g
Price
$85
Updated
2021/12/16
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4-Bromo-3-nitrobenzotrifluoride Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid

Uses

4-Bromo-3-nitrobenzotrifluoride may be used to prepare polysubstituted bisheterocycles with potential chemotherapeutic properties.

General Description

4-Bromo-3-nitrobenzotrifluoride is an organic building block.

Synthesis

121-17-5

349-03-1

Example 10: Synthesis of 4-bromo-3-nitrobenzotrifluoride from 4-chloro-3-nitrobenzotrifluoride (g); [0086] 4-chloro-3-nitrobenzotrifluoride (1 eq.) was synthesized from 4-chloro-3-nitrobenzotrifluoride (1 eq.) with a source of bromide (cuprous bromide, cupric bromide, lithium bromide, or magnesium bromide, 1 eq.) or a mixture of cuprous bromide (1 eq.) with lithium bromide (1 eq.) under the presence of benzyl cyanide, diethylene glycol dimethyl ether ( diethylene glycol dimethyl ether), acetic acid or N-methylpyrrolidone (1 mL/mmol) as solvent, and heated the reaction at 160 °C for 6 h to obtain the target product 4-bromo-3-nitrobenzotrifluoride. Table 11 shows that good selectivity was obtained using different reaction conditions, with the mixture of cuprous bromide and lithium bromide being particularly effective. Comparative experiments showed that the reaction was less effective under solvent-free conditions.

References

[1] Patent: US6635780, 2003, B1. Location in patent: Page/Page column 12
[2] Patent: US6635780, 2003, B1. Location in patent: Page/Page column 10-11
[3] Patent: US6635780, 2003, B1. Location in patent: Page/Page column 10-11
[4] Patent: US6635780, 2003, B1. Location in patent: Page/Page column 10-12
[5] Patent: US6635780, 2003, B1. Location in patent: Page/Page column 10-11

4-Bromo-3-nitrobenzotrifluoride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromo-3-nitrobenzotrifluoride Suppliers

Americas 1 China 188 Europe 3 France 1 Germany 3 India 8 Italy 1 Japan 2 Switzerland 2 United Kingdom 21 United States 30 Global 260
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from 4-Bromo-3-nitrobenzotrifluoride manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-Bromo-3-nitrobenzotrifluoride 349-03-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-07-01
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Bromo-3-nitrobenzotrifluoride 349-03-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-07
Shaanxi Dideu Medichem Co. Ltd
Product
4-Bromo-3-nitrobenzotrifluoride 349-03-1
Price
US $0.00-0.00/KG
Min. Order
50mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-08

349-03-1, 4-Bromo-3-nitrobenzotrifluorideRelated Search:

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  • Building Blocks
  • Nitro Compounds
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  • Nitrogen Compounds
  • Miscellaneous
  • Trifluoromethyl-benzene series
  • Nitro Compounds
  • Nitrogen Compounds
  • Organic Building Blocks
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