ChemicalBook > CAS DataBase List > Palbociclib-025
Palbociclib-025
- Product Name
- Palbociclib-025
- CAS No.
- 2174002-16-3
- Chemical Name
- Palbociclib-025
- Synonyms
- N-Formyl Palbociclib;Palbociclib E;Palbociclib Impurity 025;4-[6-({6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl}amino)pyridin-3-yl]piperazine-1-carbaldehyde;1-Piperazinecarboxaldehyde, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-;4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde? (Palbociclib Impurity);Palbociclib impurity 27/Palbociclib N-Formyl Impurity/4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde
- CBNumber
- CB04883289
- Molecular Formula
- C25H29N7O3
- Formula Weight
- 475.54
- MOL File
- 2174002-16-3.mol
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Palbociclib-025 Property
- Boiling point:
- 765.3±70.0 °C(Predicted)
- Density
- 1.389±0.06 g/cm3(Predicted)
- storage temp.
- -20°C, stored under nitrogen
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 5.24±0.10(Predicted)
- color
- Light Yellow to Very Dark Yellow
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Palbociclib-025 Chemical Properties,Usage,Production
Uses
Palbociclib N-Aldehyde is an intermediate in synthesizing Palbociclib N-b-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
Palbociclib-025 Preparation Products And Raw materials
Raw materials
Preparation Products
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2174002-16-3, Palbociclib-025Related Search:
4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester
Palbociclib Impurity N-Oxide
4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester
4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Palbociclib Impurity 87
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one
Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl-
6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione
Palbociclib Impurity 91
Palbociclib Impurity I
6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
Palbociclib Impurity 37
rac-trans-4-Desfluoro-4-methoxy Paroxetine Hydrochloride
Paroxetine Impurity 4
Paroxetine HCl Hemihydrate EP Impurity C HCl