ChemicalBook > CAS DataBase List > 2-Fluorophenol

2-Fluorophenol

Product Name
2-Fluorophenol
CAS No.
367-12-4
Chemical Name
2-Fluorophenol
Synonyms
1-Bromo-3-fluorobezene;O-FLUOROPHENOL;uorophenoL;2-Florophenol;2-Flurophenol;2-fluoro-pheno;2-FLUOROPHENOL;o-fluoro-pheno;2-Fluorophenole;2-Fluorophenol f
CBNumber
CB0495831
Molecular Formula
C6H5FO
Formula Weight
112.1
MOL File
367-12-4.mol
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2-Fluorophenol Property

Melting point:
16.1 °C (lit.)
Boiling point:
171-172 °C/741 mmHg (lit.)
Density 
1.256 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.511(lit.)
Flash point:
116 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
37.7g/l
form 
Liquid
pka
8.73(at 25℃)
Specific Gravity
1.256
color 
Clear colorless to light yellow-brownish
Water Solubility 
80.72g/L(25 ºC)
BRN 
1905112
Stability:
Stable. Flammable. Incompatible with strong oxidizing agents.
InChIKey
HFHFGHLXUCOHLN-UHFFFAOYSA-N
CAS DataBase Reference
367-12-4(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 2-fluoro-(367-12-4)
EPA Substance Registry System
o-Fluorophenol (367-12-4)
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Safety

Hazard Codes 
Xn,F,C,Xi,T
Risk Statements 
20/21/22-36/37/38-10-63-43-23/24/25-45-40
Safety Statements 
28-36/37-36/37/39-26-16-24/25-23-53-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
SL4530000
Hazard Note 
Flammable/Corrosive
TSCA 
T
HazardClass 
3
PackingGroup 
III
HS Code 
29081000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F12804
Product name
2-Fluorophenol
Purity
98%
Packaging
10g
Price
$45.9
Updated
2024/03/01
TCI Chemical
Product number
F0150
Product name
2-Fluorophenol
Purity
>98.0%(GC)
Packaging
25g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
F0150
Product name
2-Fluorophenol
Purity
>98.0%(GC)
Packaging
250g
Price
$101
Updated
2024/03/01
Alfa Aesar
Product number
A14979
Product name
2-Fluorophenol, 98%
Packaging
25g
Price
$54.65
Updated
2024/03/01
Alfa Aesar
Product number
A14979
Product name
2-Fluorophenol, 98%
Packaging
100g
Price
$154.65
Updated
2024/03/01
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2-Fluorophenol Chemical Properties,Usage,Production

Chemical Properties

Clear colourless to yellow liquid

Uses

2-Fluorophenol is a competitive inhibitor in the oxidation of 3,4-dihydroxyphenylalanine (L-DOPA), a catecholamine precursor that is used as a therapeutic agent for patients with ParkinsonтАЩs disease. 2-Fluorophenol is also used as a sole carbon energy source for bacteria.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Journal of the American Chemical Society, 103, p. 1964, 1981 DOI: 10.1021/ja00398a015

General Description

Liquid or crystalline solid melting at 14-16°C. Corrosive. Density 1.246 g / cm3.

Air & Water Reactions

Highly flammable.

Reactivity Profile

2-Fluorophenol reacts as a weak organic acid. May be incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction with bases. Such heating may initiate polymerization of the organic compound. Sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Nitrated very rapidly, even by dilute nitric acid.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic and irritant.

Purification Methods

Pass o-fluorophenol at least twice through a gas chromatographic column for small quantities; otherwise fractionally distil it under reduced pressure. [Beilstein 6 I 97, 6 IV 770.]

2-Fluorophenol Preparation Products And Raw materials

Raw materials

2-Nitrochlorobenzene Potassium fluoride Hydrogen

Preparation Products

3-Fluoro-4-hydroxybenzaldehyde
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2-Fluorophenol Suppliers

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View Lastest Price from 2-Fluorophenol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Fluorophenol 367-12-4
Price
US $0.00/KG
Min. Order
25KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-08
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Fluorophenol 367-12-4
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-12-02
Hebei Mujin Biotechnology Co.,Ltd
Product
2-Fluorophenol 367-12-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-09

367-12-4, 2-FluorophenolRelated Search:

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