LIDOFLAZINE, 98.5%

Product Name: LIDOFLAZINE, 98.5%
CAS No.: 3416-26-0
Chemical Name: LIDOFLAZINE, 98.5%
Synonyms: R-7904;clinium;klinium;corflazine;mcn-jr7904;lidoflazin;ordiflazine;lidoflazina;lidoflazinum;LIDOFLAZINE, 98.5%
CBNumber: CB0501936
Molecular Formula: C30H35F2N3O
Formula Weight: 491.62
MOL File: 3416-26-0.mol

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LIDOFLAZINE, 98.5% Property

Melting point:: 159-161°
Boiling point:: 632.6±55.0 °C(Predicted)
Density: 1.1322 (estimate)
storage temp.: 2-8°C
solubility: DMSO: ≥10mg/mL
pka: 14.62±0.70(Predicted)
form: powder
color: white
CAS DataBase Reference: 3416-26-0

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3
RTECS: TK7910000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L9668
Product name: Lidoflazine
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $188
Updated: 2024/03/01

Sigma-Aldrich

Product number: L9668
Product name: Lidoflazine
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $826
Updated: 2024/03/01

TRC

Product number: L397820
Product name: Lidoflazine
Packaging: 50mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-0043285
Product name: Lidoflazine
Purity: >98.0%
Packaging: 10mg
Price: $860
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007738
Product name: LIDOFLAZINE
Purity: 95.00%
Packaging: 25MG
Price: $1133.32
Updated: 2021/12/16

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LIDOFLAZINE, 98.5% Chemical Properties,Usage,Production

Chemical Properties

WHITE TO ALMOST WHITE POWDER

Originator

Clinium,Janssen,W. Germany,1969

Uses

Coronary vasodilatator;Ca++ channel activator

Uses

Lidoflazine is a L-type Ca2+ channel antagonist.Also, it is derived from 1,1''-(4-Chlorobutylidene)bis(4-fluorobenzene) (C364775), which is a derivative of Zerumbone with potential anti-tumor effects towards HeLa cancer cells.

Definition

ChEBI: 2-[4-[4,4-bis(4-fluorophenyl)butyl]-1-piperazinyl]-N-(2,6-dimethylphenyl)acetamide is a diarylmethane.

Manufacturing Process

A mixture of 6.6 parts 1-[4,4-di-(4-fluoro-phenyl)butyl]-piperazine, 4.33 parts N-(2-chloro-acetyl)-2,6-dimethyl-aniline, 3.2 parts sodium carbonate, a few crystals of potassium iodide in 200 parts 4-methyl-2-pentanone is stirred and refluxed for 70 hours. After cooling there are added 70 parts water. The organic layer is separated, dried over potassium carbonate, filtered and evaporated. The oily residue is dissolved in 80 parts diisopropylether and the solution is filtered hot. After cooling the filtrate at 0°C. the formed solid is filtered off and recystallired from 80 parts ether, yielding 1-[4,4-di-(4-fluorophenyl)butyl]-4-[(2,6-dimethylanilino-carbonyl)-methyl]-piperazine; MP 159°C to 161°C.

brand name

Angex (Janssen); Clinium (Ortho-McNeil).

Therapeutic Function

Coronary vasodilator

LIDOFLAZINE, 98.5% Preparation Products And Raw materials

Raw materials

Preparation Products

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LIDOFLAZINE, 98.5% Suppliers

China 15 Germany 1 India 1 Switzerland 1 United Kingdom 1 United States 9 Global 28

Beijing HuaMeiHuLiBiological Chemical

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Shanghai TaoSu Biochemical Technology Co., Ltd.

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Shanghai HuanChuan Industry Co.,Ltd.

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Alta Scientific Co., Ltd.

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TargetMol Chemicals Inc.

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Alfa Chemistry

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AFINE CHEMICALS LIMITED

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Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
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Country: China
ProdList: 9553
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Energy Chemical

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View Lastest Price from LIDOFLAZINE, 98.5% manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Lidoflazine 3416-26-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-11

3416-26-0, LIDOFLAZINE, 98.5%Related Search:

LIDOFLAZINE, 98.5% 1-Butylpiperazine Lidocaine N-(2,6-Diphenylmethyl)-1-piperazine acetylamine 4-Methyl-1-piperazineethanamine 4,4'-Difluorodiphenylmethane N-Aminoethylpiperazine difluanazine 2-PIPERAZIN-1-YL-ACETAMIDE 2-AMINO-N-(2,6-DIMETHYLPHENYL)ACETAMIDE (4-METHYL-PIPERAZIN-1-YL)-ACETALDEHYDE 1-(4-PHENYLBUTYL)-PIPERAZINE CHEMBRDG-BB 5668895 1-[4,4-bis(4-fluorophenyl)butyl]piperazine MONOETHYLGLYCINEXYLIDIDE 4-(4-FLUOROPHENYL)BUTAN-1-AMINE 1-Piperazineethanamine,4-ethyl-(9CI) 1-Piperazineethanamine,N,4-dimethyl-(9CI)

6’-xylidide,4-(4,4-bis(p-fluorophenyl)butyl)-1-piperazineaceto-2

clinium

corflazine

klinium

lidoflazin

lidoflazina

lidoflazinum

mcn-jr7904

ordiflazine

LIDOFLAZINE, 98.5%

4-[4,4-Bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-1-piperazineacetamide

R-7904

Lidoflazine Solution, 1000ppm

Lidoflazine Solution, 100ppm

1-(4,4-bis(4-fluorofenil)butil)-4-((2,6-dimetilanilinocarbonil)metil)piperaz

1-piperazineacetamide,4-(4,4-bis(4-fluorophenyl)butyl)-n-(2,6-dimethylphenyl

4-(4,4-bis(p-fluorophenyl)butyl)-1-piperazineaceto-2’,6’-xylidide

Lidoflazine >=98% (HPLC), powder

LIDOFLAZINE, 98.5% USP/EP/BP

3416-26-0

C30H35F2N3O