LIDOFLAZINE, 98.5%
- Product Name
- LIDOFLAZINE, 98.5%
- CAS No.
- 3416-26-0
- Chemical Name
- LIDOFLAZINE, 98.5%
- Synonyms
- R-7904;clinium;klinium;corflazine;mcn-jr7904;lidoflazin;ordiflazine;lidoflazina;lidoflazinum;LIDOFLAZINE, 98.5%
- CBNumber
- CB0501936
- Molecular Formula
- C30H35F2N3O
- Formula Weight
- 491.62
- MOL File
- 3416-26-0.mol
LIDOFLAZINE, 98.5% Property
- Melting point:
- 159-161°
- Boiling point:
- 632.6±55.0 °C(Predicted)
- Density
- 1.1322 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥10mg/mL
- pka
- 14.62±0.70(Predicted)
- form
- powder
- color
- white
- CAS DataBase Reference
- 3416-26-0
N-Bromosuccinimide Price
- Product number
- L9668
- Product name
- Lidoflazine
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $188
- Updated
- 2024/03/01
- Product number
- L9668
- Product name
- Lidoflazine
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $826
- Updated
- 2024/03/01
- Product number
- L397820
- Product name
- Lidoflazine
- Packaging
- 50mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- CS-0043285
- Product name
- Lidoflazine
- Purity
- >98.0%
- Packaging
- 10mg
- Price
- $860
- Updated
- 2021/12/16
- Product number
- API0007738
- Product name
- LIDOFLAZINE
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $1133.32
- Updated
- 2021/12/16
LIDOFLAZINE, 98.5% Chemical Properties,Usage,Production
Chemical Properties
WHITE TO ALMOST WHITE POWDER
Originator
Clinium,Janssen,W. Germany,1969
Uses
Coronary vasodilatator;Ca++ channel activator
Uses
Lidoflazine is a L-type Ca2+ channel antagonist.Also, it is derived from 1,1''-(4-Chlorobutylidene)bis(4-fluorobenzene) (C364775), which is a derivative of Zerumbone with potential anti-tumor effects towards HeLa cancer cells.
Definition
ChEBI: 2-[4-[4,4-bis(4-fluorophenyl)butyl]-1-piperazinyl]-N-(2,6-dimethylphenyl)acetamide is a diarylmethane.
Manufacturing Process
A mixture of 6.6 parts 1-[4,4-di-(4-fluoro-phenyl)butyl]-piperazine, 4.33 parts N-(2-chloro-acetyl)-2,6-dimethyl-aniline, 3.2 parts sodium carbonate, a few crystals of potassium iodide in 200 parts 4-methyl-2-pentanone is stirred and refluxed for 70 hours. After cooling there are added 70 parts water. The organic layer is separated, dried over potassium carbonate, filtered and evaporated. The oily residue is dissolved in 80 parts diisopropylether and the solution is filtered hot. After cooling the filtrate at 0°C. the formed solid is filtered off and recystallired from 80 parts ether, yielding 1-[4,4-di-(4-fluorophenyl)butyl]-4-[(2,6-dimethylanilino-carbonyl)-methyl]-piperazine; MP 159°C to 161°C.
brand name
Angex (Janssen); Clinium (Ortho-McNeil).
Therapeutic Function
Coronary vasodilator
LIDOFLAZINE, 98.5% Preparation Products And Raw materials
Raw materials
Preparation Products
LIDOFLAZINE, 98.5% Suppliers
View Lastest Price from LIDOFLAZINE, 98.5% manufacturers
- Product
- Lidoflazine 3416-26-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-11