ChemicalBook > CAS DataBase List > 9-Oxo-10(9H)-acridineacetic acid
9-Oxo-10(9H)-acridineacetic acid
- Product Name
- 9-Oxo-10(9H)-acridineacetic acid
- CAS No.
- 38609-97-1
- Chemical Name
- 9-Oxo-10(9H)-acridineacetic acid
- Synonyms
- ACRIDONE ACETIC ACID;Cridanimod;10-carboxymethyl-9-acridanone;10-Cma;XBIO-101;AI3-05733;HSDB 2647;Aids000901;Aids-000901;Brn 0227508
- CBNumber
- CB0502504
- Molecular Formula
- C15H11NO3
- Formula Weight
- 253.25
- MOL File
- 38609-97-1.mol
More
Less
9-Oxo-10(9H)-acridineacetic acid Property
- Melting point:
- ~289 °C (dec.)
- Boiling point:
- 486.6±34.0 °C(Predicted)
- Density
- 1.362
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Aqueous Base (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 3.69±0.10(Predicted)
- color
- Pale Yellow to Light Yellow
- λmax
- 410nm(H2O)(lit.)
- BRN
- 227508
- InChI
- InChI=1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)
- InChIKey
- UOMKBIIXHQIERR-UHFFFAOYSA-N
- SMILES
- C1=C2C(N(CC(O)=O)C3=C(C2=O)C=CC=C3)=CC=C1
- CAS DataBase Reference
- 38609-97-1(CAS DataBase Reference)
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 17927
- Product name
- 9-Oxo-10(9H)-acridineacetic acid
- Purity
- for HPLC derivatization, ≥99.0% (T)
- Packaging
- 250mg
- Price
- $317
- Updated
- 2024/03/01
TCI Chemical
- Product number
- O0432
- Product name
- 9-Oxoacridine-10-acetic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $78
- Updated
- 2024/03/01
TCI Chemical
- Product number
- O0432
- Product name
- 9-Oxoacridine-10-acetic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $234
- Updated
- 2024/03/01
TRC
- Product number
- O870098
- Product name
- 9-Oxo-10(9H)-acridineacetic acid
- Packaging
- 250mg
- Price
- $140
- Updated
- 2021/12/16
TRC
- Product number
- O870098
- Product name
- 9-Oxo-10(9H)-acridineacetic acid
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
More
Less
9-Oxo-10(9H)-acridineacetic acid Chemical Properties,Usage,Production
Definition
Acriridone derivatives have become a research hotspot in the field of medicine in recent years due to their good antibacterial, anti-inflammatory, anti-malarial, and anti-cancer activities. This type of compound has a rigid planar structure of a macrocyclic conjugated system and can be embedded or Electrostatic attraction binds to DNA. Among them, 9-aminoacridine derivatives have good pharmacological and biological activities, and some of them have been used clinically as DNA embedding reagents. As an important pharmaceutical intermediate, 9-Oxo-10(9H)-acridineacetic acid has also received increasing attention. Cridanimod (9-Oxo-10(9H)-acridineacetic acid) is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer.
Description
9-Oxo-10(9H)-acridineacetic acid , also known as Cridanimod or XBIO-101, is a small molecule that can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. This could increase the sensitivity of endometrial cancer cells to progestin monotherapy. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone (LH) release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen release from the ovaries. This leads to an inhibition of cellular growth in estrogen-dependent tumor cells.
Uses
9-Oxo-10(9H)-acridineacetic acid is a reagent for pre-column derivatization of amino acids for fluorescent determination in HPLC and it is also a building block in pharmaceutics.
Definition
ChEBI: Cridanimod is a member of acridines. It is functionally related to an acridone.
storage
Store at +4°C
9-Oxo-10(9H)-acridineacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
9-Oxo-10(9H)-acridineacetic acid Suppliers
- Tel
- 0371-67897870 18339906974
- Fax
- 0371-63507390
- 2130541246@qq.com
- Country
- China
- ProdList
- 107
- Advantage
- 58
- Tel
- 15523000485
- xingcanyaoye@sina.com
- Country
- China
- ProdList
- 1686
- Advantage
- 58
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24539
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44751
- Advantage
- 61
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9984
- Advantage
- 60
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- zhangsn@titansci.com
- Country
- China
- ProdList
- 14113
- Advantage
- 59
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14443
- Advantage
- 57
- Tel
- 027-85736489
- Fax
- 86-27-85736485
- info@kemiworks.net
- Country
- China
- ProdList
- 542
- Advantage
- 57
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Country
- China
- ProdList
- 4550
- Advantage
- 62
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4941
- Advantage
- 60
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9901
- Advantage
- 58
- Tel
- 18521735133 18521732826;
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25015
- Advantage
- 65
- Tel
- 86-13605431940 13605431940
- Fax
- 0086-0543-2240079
- zpmxchemical@126.com
- Country
- China
- ProdList
- 2002
- Advantage
- 62
- Tel
- 021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7934
- Advantage
- 58
- Tel
- 0570-3066667
- Fax
- 0570-3063388
- Country
- China
- ProdList
- 3933
- Advantage
- 58
- Tel
- 023-62879767 13996269627;
- Fax
- +86-28-84559521
- sales@conier.com
- Country
- China
- ProdList
- 294
- Advantage
- 56
- Tel
- 021-60549325 18616193163
- Fax
- 021-33250306
- Country
- China
- ProdList
- 4528
- Advantage
- 56
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- 422131432@qq.com
- Country
- China
- ProdList
- 9986
- Advantage
- 55
- Tel
- 021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3993
- Advantage
- 60
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9636
- Advantage
- 58
- Tel
- 13598610367
- Fax
- QQ:2468833170
- 2841375912@qq.com
- Country
- China
- ProdList
- 2798
- Advantage
- 52
- Tel
- 025-66113011 18112977050
- cb6@aikonchem.com
- Country
- China
- ProdList
- 16687
- Advantage
- 50
- Tel
- Fax
- -
- xg01_gj@163.com
- Country
- China
- ProdList
- 9503
- Advantage
- 50
- Tel
- 027-027-59207879 18140587686
- Fax
- QQ：1972026995
- kf@3600chem.com
- Country
- China
- ProdList
- 4699
- Advantage
- 55
- Tel
- 0570-8789886 18892685668
- Fax
- 0570-8789985
- info@rundongchemical.com
- Country
- China
- ProdList
- 3991
- Advantage
- 60
- Tel
- 15618758386 15618758386
- Fax
- QQ:3004479444
- sales3@myuchem.com
- Country
- China
- ProdList
- 2021
- Advantage
- 55
- Tel
- 021-61984905-1 18016477331
- synchempharma@aliyun.com
- Country
- China
- ProdList
- 6454
- Advantage
- 55
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7998
- Advantage
- 55
- Tel
- 18915409046
- Fax
- 0510-86566870
- 1102409417@qq.com
- Country
- China
- ProdList
- 272
- Advantage
- 55
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- sales@chemwill.com
- Country
- China
- ProdList
- 1975
- Advantage
- 58
- Tel
- 0371-55289822 18737195735
- Fax
- QQ：2370407954
- 2370407954@qq.com
- Country
- China
- ProdList
- 2000
- Advantage
- 55
- Tel
- 400-1166-196 18502815961
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 14623
- Advantage
- 60
- Tel
- 18221735425
- sales@xinpingchem.com
- Country
- China
- ProdList
- 9951
- Advantage
- 58
- Tel
- 021-2022843681 15618226720
- Fax
- +86-21-51601218
- chaolaichem@foxmail.com
- Country
- China
- ProdList
- 7565
- Advantage
- 58
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
- Country
- China
- ProdList
- 29797
- Advantage
- 68
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131981
- Advantage
- 58
- Tel
- 0551-65171243 13810511747
- kuer@kuerhuaxue.com
- Country
- China
- ProdList
- 2997
- Advantage
- 55
- Tel
- 0531-82956131 15069164249
- Fax
- 0531-82956625
- jnjspharm@126.com
- Country
- China
- ProdList
- 1519
- Advantage
- 55
- Tel
- +86-21-5877 1921
- Fax
- +86-21-5877 1925
- info@chemofchina.com
- Country
- China
- ProdList
- 9661
- Advantage
- 55
- Tel
- 0371-0371-86259281 15981966935
- Fax
- 0371-86259281
- jacschem@163.com
- Country
- China
- ProdList
- 2010
- Advantage
- 58
- Tel
- 15003910607
- Fax
- -
- jzstarchem@126.com
- Country
- China
- ProdList
- 84
- Advantage
- 58
- Tel
- 021-37581181
- Fax
- 021-57456066
- sales@chem-mall.com
- Country
- China
- ProdList
- 10335
- Advantage
- 58
- Tel
- 027-87466105 15377573527
- 2678564200@qq.com
- Country
- China
- ProdList
- 17997
- Advantage
- 58
- Tel
- 0570-3062289 13819008176 15068926975
- Fax
- 0570-3063388
- 527757556@qq.com
- Country
- China
- ProdList
- 2959
- Advantage
- 58
- Tel
- 400-6387771-6038 18902104717
- sales@heowns.com
- Country
- China
- ProdList
- 20512
- Advantage
- 60
- Tel
- 021-37590756 57450129
- Fax
- 021-57450128
- Country
- China
- ProdList
- 4287
- Advantage
- 58
- Tel
- 027-51831887 15337167856
- Fax
- 027-51837635 QQ1165326703
- hubeixinyuanshun@163.com
- Country
- China
- ProdList
- 10305
- Advantage
- 58
- Tel
- 13370351217 kungfu1217@1
- Fax
- QQ1400885609
- kungfu1217@163.com
- Country
- China
- ProdList
- 9693
- Advantage
- 58
- Tel
- 0510-0510-66227179 18921203887
- Fax
- +86-0510-66227179 QQ:2200317867
- sales@ruishipharm.com
- Country
- China
- ProdList
- 751
- Advantage
- 58
- Tel
- 0371-0371-63315541 13323832564
- Fax
- QQ:3001332135
- 3001332135@qq.com
- Country
- China
- ProdList
- 8922
- Advantage
- 58
More
Less
View Lastest Price from 9-Oxo-10(9H)-acridineacetic acid manufacturers
Shaanxi TNJONE Pharmaceutical Co., Ltd
- Product
- 9-Oxo-10(9H)-acridineacetic acid 38609-97-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2024-04-08
Henan Fengda Chemical Co., Ltd
- Product
- 9-Oxo-10(9H)-acridineacetic acid 38609-97-1
- Price
- US $50.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-22
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 9-Oxo-10(9H)-acridineacetic acid 38609-97-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
38609-97-1, 9-Oxo-10(9H)-acridineacetic acidRelated Search:
Glycine
Citric acid
2-ETHOXY-6,9-DIAMINOACRIDINE
Amsacrine hydrochloride
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
9(10H)-ACRIDONE
Basic Orange 14
Ethyl 2-(Chlorosulfonyl)acetate
Ethyl acetate
Quinacridone
Folic acid
Ascoric Acid
Chloroacetic acid
Acetic anhydride
CARBAZINE
10-METHYL-9(10H)-ACRIDONE
(DIPHENYLAMINO)ACETIC ACID
Camedon