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SALVINORIN A

Product Name
SALVINORIN A
CAS No.
83729-01-5
Chemical Name
SALVINORIN A
Synonyms
Salvinorin;Divinorin A;SALVINORIN A;SALVINORIN A(P);Salvinorin A solution;(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester;(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester;2H-Naphtho[2,1-c]pyran-7-carboxylicacid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-,methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)-;[2S-(2α,4aα,6aβ,7β,9β,10aα,10bβ)]-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-diMethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic Acid Methyl Ester
CBNumber
CB0506991
Molecular Formula
C23H28O8
Formula Weight
432.46
MOL File
83729-01-5.mol
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SALVINORIN A Property

Melting point:
238-240° (Ortega); mp 242-244° (Valdes, 1984)
alpha 
D22 -45.3° (c = 8.530 in CHCl3); D25 -41° (c = 1 in CHCl3)
Boiling point:
563.8±50.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
Flash point:
2℃
storage temp. 
−20°C
solubility 
DMSO: ≥10mg/mL
form 
powder
color 
white
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Safety

Hazard Codes 
F,Xn
Risk Statements 
11-20/21/22-36
Safety Statements 
22-24/25-36/37-16
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
QL6127142
Hazardous Substances Data
83729-01-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S8071
Product name
Salvinorin A
Purity
≥98% (HPLC), powder
Packaging
1mg
Price
$210
Updated
2024/03/01
Sigma-Aldrich
Product number
5.08159
Product name
Salvinorin A - CAS 83729-01-5 - Calbiochem
Packaging
1MG
Price
$177
Updated
2023/06/20
Sigma-Aldrich
Product number
S-012
Product name
Salvinorin A solution
Purity
1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$164
Updated
2022/05/15
Cayman Chemical
Product number
11487
Product name
Salvinorin A
Purity
≥95%
Packaging
1mg
Price
$132
Updated
2024/03/01
Cayman Chemical
Product number
11487
Product name
Salvinorin A
Purity
≥95%
Packaging
5mg
Price
$494
Updated
2024/03/01
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SALVINORIN A Chemical Properties,Usage,Production

Description

Salvinorin A (Item No. 11487) is an analytical reference material categorized as a diterpene. It is a hallucinogen derived from S. divinorum that has been used in the traditional spiritual practices of the Mazatec Indians and as a recreational drug. This product is intended for research and forensic applications.

Uses

Salvinorin A is a potent and selective kappa-opioid receptor agonist. Salvinorin A has been reported to be brain-penetrant and displays psychoactive properties; hallucinogen.

Uses

Salvinorin A is a hallucinogenic derived from the S. divinorum plant used in traditional spiritual practices of the Mazatec Indians and now gaining popularity as a recreational drug. Unlike other hallucinogens, which mediate their effects through serotonin 5-HT2A receptors, salvinorin A is a potent, selective κ-opioid receptor agonist (Ki = 2.4 nM; EC50 = 1.8 nM). This product is intended for forensic and research applications.In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions.

Uses

In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions.

Definition

ChEBI: A natural product found in Salvia divinorum.

Biological Activity

Potent naturally occuring non-nitrogenous κ -opioid selective agonist that displays high affinity at both native (K i = 4.3 nM) and cloned (K i = 16 nM) κ -opioid receptors. Also exhibits allosteric modulation of μ -opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties.

Biochem/physiol Actions

Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

SALVINORIN A Preparation Products And Raw materials

Raw materials

Preparation Products

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SALVINORIN A Suppliers

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83729-01-5, SALVINORIN ARelated Search:


  • Salvinorin A solution
  • [2S-(2α,4aα,6aβ,7β,9β,10aα,10bβ)]-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-diMethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic Acid Methyl Ester
  • Salvinorin
  • 2H-Naphtho[2,1-c]pyran-7-carboxylicacid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-,methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)-
  • SALVINORIN A(P)
  • (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
  • (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
  • Divinorin A
  • SALVINORIN A
  • 83729-01-5
  • Neurochcemicals
  • Agonist
  • Heterocycles
  • Opioids
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Opioid receptor and opioid-like receptor