SALVINORIN A
- Product Name
- SALVINORIN A
- CAS No.
- 83729-01-5
- Chemical Name
- SALVINORIN A
- Synonyms
- Salvinorin;Divinorin A;SALVINORIN A;SALVINORIN A(P);Salvinorin A solution;(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester;(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester;2H-Naphtho[2,1-c]pyran-7-carboxylicacid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-,methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)-;[2S-(2α,4aα,6aβ,7β,9β,10aα,10bβ)]-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-diMethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic Acid Methyl Ester
- CBNumber
- CB0506991
- Molecular Formula
- C23H28O8
- Formula Weight
- 432.46
- MOL File
- 83729-01-5.mol
SALVINORIN A Property
- Melting point:
- 238-240° (Ortega); mp 242-244° (Valdes, 1984)
- alpha
- D22 -45.3° (c = 8.530 in CHCl3); D25 -41° (c = 1 in CHCl3)
- Boiling point:
- 563.8±50.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- Flash point:
- 2℃
- storage temp.
- −20°C
- solubility
- DMSO: ≥10mg/mL
- form
- powder
- color
- white
Safety
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20/21/22-36
- Safety Statements
- 22-24/25-36/37-16
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 3
- RTECS
- QL6127142
- Hazardous Substances Data
- 83729-01-5(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P235Store in a well-ventilated place. Keep cool.
N-Bromosuccinimide Price
- Product number
- S8071
- Product name
- Salvinorin A
- Purity
- ≥98% (HPLC), powder
- Packaging
- 1mg
- Price
- $210
- Updated
- 2024/03/01
- Product number
- 5.08159
- Product name
- Salvinorin A - CAS 83729-01-5 - Calbiochem
- Packaging
- 1MG
- Price
- $177
- Updated
- 2023/06/20
- Product number
- S-012
- Product name
- Salvinorin A solution
- Purity
- 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $164
- Updated
- 2022/05/15
- Product number
- 11487
- Product name
- Salvinorin A
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $132
- Updated
- 2024/03/01
- Product number
- 11487
- Product name
- Salvinorin A
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $494
- Updated
- 2024/03/01
SALVINORIN A Chemical Properties,Usage,Production
Description
Salvinorin A (Item No. 11487) is an analytical reference material categorized as a diterpene. It is a hallucinogen derived from S. divinorum that has been used in the traditional spiritual practices of the Mazatec Indians and as a recreational drug. This product is intended for research and forensic applications.
Uses
Salvinorin A is a potent and selective kappa-opioid receptor agonist. Salvinorin A has been reported to be brain-penetrant and displays psychoactive properties; hallucinogen.
Uses
Salvinorin A is a hallucinogenic derived from the S. divinorum plant used in traditional spiritual practices of the Mazatec Indians and now gaining popularity as a recreational drug. Unlike other hallucinogens, which mediate their effects through serotonin 5-HT2A receptors, salvinorin A is a potent, selective κ-opioid receptor agonist (Ki = 2.4 nM; EC50 = 1.8 nM). This product is intended for forensic and research applications.In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions.
Uses
In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions.
Definition
ChEBI: A natural product found in Salvia divinorum.
Biological Activity
Potent naturally occuring non-nitrogenous κ -opioid selective agonist that displays high affinity at both native (K i = 4.3 nM) and cloned (K i = 16 nM) κ -opioid receptors. Also exhibits allosteric modulation of μ -opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties.
Biochem/physiol Actions
Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.