ChemicalBook > CAS DataBase List > Lipase

Lipase

Description References Background

Product Name: Lipase
CAS No.: 9001-62-1
Chemical Name: Lipase
Synonyms: LIPASE PS;PANCRELIPASE;LIPASE ENZYME;Lipozyme TL IM;LIPASE AK;Lipase from porcine pancreas;Lipozyme RM;thermomyces lanuginosus;Lipase from Thermus thermophilus;LIPASE MML
CBNumber: CB0664101
Molecular Formula: C11H9N3NaO2+
Formula Weight: 238.19783
MOL File: 9001-62-1.mol

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Lipase Property

Density: 1.2
vapor pressure: 0.004Pa at 25℃
storage temp.: 2-8°C
solubility: H₂O: 2 mg/mL, hazy with insoluble particles, faintly yellow
form: solution
color: yellow-brown
biological source: whe at (germ)
Water Solubility: It is soluble in water.
Merck: 13,5533
Specific Activity: 5-15units/mg solid
Stability:: Moisture sensitive. Incompatible with strong oxidizing agents.
InChI: InChI=1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;
InChIKey: QWZUIMCIEOCSJF-CHHCPSLASA-N
SMILES: [Na+].O([H])C1=C([H])C(C([H])=C([H])/C/1=N/N([H])C1=C([H])C([H])=C([H])C([H])=N1)=O
LogP: -1.3 at 20℃
CAS DataBase Reference: 9001-62-1
EPA Substance Registry System: Lipase, triacylglycerol (9001-62-1)

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Safety

Hazard Codes: B,Xn
Risk Statements: 20/21/22
Safety Statements: 22-24/25-36/37-36
WGK Germany: 3
RTECS: TO9776500
F: 3-10-21
TSCA: Yes
HS Code: 35079020

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRE0028
Product name: Lipase from human pancreas
Packaging: 100 units
Price: $697
Updated: 2025/07/31

Sigma-Aldrich

Product number: L8525
Product name: Lipase from Candida rugosa
Purity: lyophilized powder, ≥40,000?units/mg protein
Packaging: 1000000units
Price: $163
Updated: 2025/07/31

Sigma-Aldrich

Product number: L8525
Product name: Lipase from Candida rugosa
Purity: lyophilized powder, ≥40,000?units/mg protein
Packaging: 5000000units
Price: $627
Updated: 2025/07/31

Sigma-Aldrich

Product number: L0382
Product name: Lipase from porcine pancreas
Purity: Type VI-S, ≥20,000?units/mg protein, lyophilized powder
Packaging: 100000units
Price: $301
Updated: 2025/07/31

Sigma-Aldrich

Product number: L0382
Product name: Lipase from porcine pancreas
Purity: Type VI-S, ≥20,000?units/mg protein, lyophilized powder
Packaging: 1000000units
Price: $2160
Updated: 2025/07/31

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Lipase Chemical Properties,Usage,Production

Description

Lipase is an enzyme and belongs to the class of hydrolase. Lipase is produced in the pancreas, mouth, and stomach. It catalyzes the hydrolysis of triglycerides to glycerol and free fatty acids. The body uses lipase to break down fats in food so they can be absorbed in the intestines.
Lipases are widely employed to catalyze hydrolysis, alcoholysis, esterification, interesterification, acidolysis and transesterification of carboxylic esters. Their unique characteristics include substrate specificity, stereospecificity, regioselectivity and ability to catalyze a heterogeneous reaction at the interface of water soluble and water insoluble systems. Lipases are used as flavor and aroma constituents in the food industry, to produce valuable oleo chemical species for diesel engines, as additives in cosmetic formulations, to remove the pitch from pulp produced in the paper industry, for the hydrolysis of milk fat in the dairy industry, to remove non-cellulosic impurities from raw cotton before further processing into dyed and finished products, for the drug formulations in the pharmaceutical industry, and to remove subcutaneous fat in the leather industry. Lipases are also used to diagnose pancreatitis in patients. Clinically lipases help a person who has cystic fibrosis, Alzheimer's disease, atherosclerosis and act as a candidate target for cancer prevention and therapy. Lipases are also used to treat obesity in recent years.

References

[1] http://www.umm.edu/health/medical/altmed/supplement/lipase
[2] Tianwei Tan, Jike Lu, Kaili Nie, Li Deng, Fang Wang (2010) Biodiesel production with immobilized lipase: A reveiw, 28, 628-634
[3] G. D. Haki, S. K. Rakshit (2003) Developments in industrially important thermostable enzymes: a rview, 89, 17-34
[4] Jack M. Goldberg (1976) Diagnostic use of pancreatic lipase determination by radial enzyme diffusion, and design of a routine pancreatic profile, 22, 638-642
[5] H. Loli, SK. Narwal, NK. Saun, R. Gupta (2015) Lipases in medicine: an overview, 15, 1209-1216

Description

Lipase is obtained from two primary sources: (1) the edible fore stomach tissue of calves, kids, or lambs and; (2 ) animal pancreatic tissue. It is produced as purified edible tissue preparations or as aqueous extracts. It is dispersible in water and insoluble in alcohol. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Description

Produced by the controlled fermentation of Aspergillus niger var. as an off-white to tan amorphous powder. Soluble in water (the solution is usually light yellow), but practically insoluble in alco hol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Description

Produced by the controlled fermentation of Aspergillus oryzae var. as an off-white to tan amorphous powder or a liquid. Soluble in water (the solution is usually light yellow), but practically insol uble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Description

Produced by the controlled fermentation of Candida rugosa as an off-white to tan powder. Soluble in water but practically insoluble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Chemical Properties

powder

Uses

To split fats without damaging sensitive constituents, such as vitamins or unsaturated fatty acids. In food processing for flavor improvement; in detergents for the improvement of cleaning action. For review of industrial applications of microbial lipases, see Seitz, J. Am. Oil Chem. Soc. 51, 12 (1974).

Uses

Trans fatty acids (TFAs) are fatty acids with at least one double bond in (E)- configuration. The consumption of TFAs increases the risk of coronary heart diseases. Thus, their concentrations in lipid-containing products should be reduced [87]. Naturally, TFAs occur in small amounts in meat and milk of ruminants, but the most significant concentrations of TFAs develop during partial hydrogenation and deodorization of fats [88]. The formation of TFAs during fat hardening can be avoided by lipase catalyzed transesterification to increase the slip melting points of fats.
For enzymatic transesterification between different lipids, triacylglycerol lipases (triacylglycerol acylhydrolase, EC 3.1.1.3) acting on the SN1 and SN3 positions of the triglyceride are used. Various lipases have been applied for the production of table margarine out of fat-oil blends. Lipases of the ascomycetes Thermomyces lanuginosa and Rhizomucor miehei, as well as a lipase of the proteobacterium Pseudomonas sp., were used for transesterification of fat blends consisting of palm stearin and vegetable oil. Fully hydrogenated oils in blends with vegetable oils also have been used. In all studies, an increase of the slip melting points and the solid fat content was achieved in the fat-oil blend, thus indicating an alternative method for fat hardening via hydrogenation.

Uses

Lipase, is used as a catalyst in the preparation of biodiesels?and in the preparation of esters of chiral epoxy alcohols.?Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel.

Definition

lipase: An enzyme secreted by thepancreas and the glands of the smallintestine of vertebrates that catalysesthe breakdown of fats into fatty acidsand glycerol.

General Description

Pancrelipase (Cotazym) has agreater lipolytic action than other pancreatic enzyme preparations.Hence, it is used to help control steatorrhea and inother conditions in which pancreatic insufficiency impairsthe digestion of fats in the diet.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Amano lipase M is capable of catalyzing Michael addition of pyrimidine with disaccharide acrylates in organic media.

Background

Lipase (EC 3.1.1.3) is a ubiquitous enzyme that catalyzes the hydrolysis of fats and oil. The Serratia marcescens lipase is recognized for its excellent enantioselectivity in biocatalytic hydrolysis of trans-3-(4-methoxyphynyl) glycidic acid methyl ester [(±)-MPGM] to produce (2R, 3S)-3-(4-methoxyphenyl) glycidic acid methyl ester [(-)-MPGM].

Lipase Preparation Products And Raw materials

Raw materials

Chloroform Ammonium sulfate

Preparation Products

((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one MONASCUS RED Linolenic acid (4S)-4-hydroxy-3-methyl-2-prop-2-ynyl-cyclopent-2-en-1-one S-α-cyano-3-phenoxy benzyl alcohol CAPSANTHIN CHILLIORANGE (4S)-HYDROXY-3-METHYL-2-(2-PROPENYL)-2-CYCLOPENTENE-1-ONE cellulase Glycerides, C10-18 Enzyme-modified milkfat

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View Lastest Price from Lipase manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Lipase 9001-62-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500kg/month
Release date: 2021-07-20

Hebei Chuanghai Biotechnology Co., Ltd

Product: Lipase 9001-62-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-14

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: Lipase 9001-62-1
Price: US $1000.00-700.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-14

9001-62-1, LipaseRelated Search:

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Palatase? 20,000L

Lipolase 100L

Lipase–Agarose 4% beaded agarose. from wheat germ

LIPASE FROM CANDIDA CYLINDRACEA, ~2 U/MG

LIPASE FROM PSEUDOMONAS FLUORESCENS, ~300 U/MG*

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LIPASE, >4 U/MG*

LIPASE TYPE VI-S FROM PORCINE PANCREAS

LIPASE FROM RHIZOPUS DELEMAR POWDER AP

LIPASE FROM RHIZOPUS ORYZAE ~12 U/MG*

LIPASE FROM PSEUDOMONAS FLUORESCENS, ~40 U/MG*

LIPASE, RECOMBINANT, FROM*THERMOMYCES LA

LIPASE FROM PSEUDOMONAS FLUORESCENS, ~35 00 U/MG

LIPASE FROM PENICILLIUM ROQUEFORTI ~150 U/G

Lipase form Candida antarctica

LIPASE FROM MUCOR JAVANICUS, 5 U/G

LIPASE FROM ASPERGILLUS ORYZAE, ~50 U/MG

LIPASE FROM MUCOR MIEHEI

LIPASE FROM CANDIDA LIPOLYTICA, 1 U/G

LIPASE FROM MUCOR JAVANICUS

Lipase A Candida antarctica, recombinant from Aspergillus oryzae

LIPASE AK, FROM PSEUDOMONAS FLUORE

LIPASE FROM PENICILLIUM CAMEMBERTI 5 U/G*

LIPASE TYPE II CRUDE FROM*PORCINE PANCRE AS

LIPASE FROM CANDIDA CYLINDRACEA, LYOPH., ~30 U/MG

LIPASE M, FROM MUCOR JAVANICUS

LIPASE FROM CANDIDA ANTARCTICA APPROX.