METHYL 2-AMINO-5-BROMOBENZOATE

Product Name: METHYL 2-AMINO-5-BROMOBENZOATE
CAS No.: 52727-57-8
Chemical Name: METHYL 2-AMINO-5-BROMOBENZOATE
Synonyms: AURORA KA-6223;LABOTEST-BB LT00454801;METHYL 5-BROMOANTHRANILATE;5-BROMO METHYL ANTHRANILATE;METHYL 2-AMINO-5-BROMOBENZOATE;Methyl 5-Bromoanthranilate >Methyl 2-aMino-5-broMobenzoate 96%;Methyl 2-amino-5-bromobenzoate,98%;5-BROMOANTHRANILIC ACID METHYL ESTER;2-AMINO-5-BROMOBENZOIC ACID METHYL ESTER
CBNumber: CB0666923
Molecular Formula: C8H8BrNO2
Formula Weight: 230.06
MOL File: 52727-57-8.mol

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METHYL 2-AMINO-5-BROMOBENZOATE Property

Melting point:: 72-74 °C(lit.)
Boiling point:: 286.3±20.0 °C(Predicted)
Density: 1.578±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO, Methanol
pka: 1.76±0.10(Predicted)
form: Solid
color: White
Water Solubility: Soluble in water.
BRN: 972720
InChI: InChI=1S/C8H8BrNO2/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4H,10H2,1H3
InChIKey: QVNYNHCNNGKULA-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=CC(Br)=CC=C1N
CAS DataBase Reference: 52727-57-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-37/38-36
Safety Statements: 26-36-37/39
WGK Germany: 3
HS Code: 29224999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 528811
Product name: Methyl 2-amino-5-bromobenzoate
Purity: 96%
Packaging: 25g
Price: $78
Updated: 2025/07/31

TCI Chemical

Product number: B1988
Product name: Methyl 5-Bromoanthranilate
Purity: >99.0%(GC)
Packaging: 5g
Price: $49
Updated: 2025/07/31

TCI Chemical

Product number: B1988
Product name: Methyl 5-Bromoanthranilate
Purity: >99.0%(GC)
Packaging: 25g
Price: $150
Updated: 2025/07/31

TRC

Product number: M285715
Product name: Methyl 2-amino-5-bromobenzoate
Packaging: 5g
Price: $50
Updated: 2021/12/16

AK Scientific

Product number: J98082
Product name: Methyl 2-amino-5-bromobenzoate
Packaging: 5g
Price: $10
Updated: 2021/12/16

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METHYL 2-AMINO-5-BROMOBENZOATE Chemical Properties,Usage,Production

Chemical Properties

White to light yellow crystal powder

Uses

Methyl 2-amino-5-bromobenzoate acts as a potential PqsD inhibitor against pseudomonas aeruginosa infections. It is also used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors. It is involved in plant growth-regulator activity.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 7055, 1994 DOI: 10.1016/0040-4039(94)88224-X

General Description

Molecules of methyl 2-amino-5-bromobenzoate are linked by N-H...O bonds and consists of zigzag chains running along the b-axis direction. The nonlinear optical single crystal of M2A5B grown by Sankaranarayanan-Ramasamy (SR) Unidirectional growth method shows good optical transparency and mechanical stability.

Synthesis

134-20-3

52727-57-8

1. Add carbon tetrachloride (100 mL) and methyl phthalate (149 mmol) to a 250 mL four-neck flask with stirring initiated. Bromine (156.45 mmol) was added slowly dropwise. After the dropwise addition, the reaction progress was monitored by HPLC. After completion of the reaction, the reaction solution was filtered and the resulting filter cake was washed with 200 mL of isopropyl ether and dried to give a yellow solid product. The purity of the product was 96.5% and the yield was 90%.

References

[1] Patent: CN108164469, 2018, A. Location in patent: Paragraph 0100; 0101
[2] Patent: CN107089919, 2017, A. Location in patent: Paragraph 0052; 0053; 0054; 0055
[3] Synthetic Communications, 2007, vol. 37, # 4, p. 581 - 585
[4] Organic and Biomolecular Chemistry, 2017, vol. 15, # 21, p. 4644 - 4654

METHYL 2-AMINO-5-BROMOBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 2-AMINO-5-BROMOBENZOATE Suppliers

Americas 1 Austria 1 Belgium 1 China 193 Europe 1 Germany 4 India 30 Japan 2 Switzerland 3 Ukraine 1 United Kingdom 17 United States 25 Global 279

Dalian lichuang Chemical Co., Ltd

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View Lastest Price from METHYL 2-AMINO-5-BROMOBENZOATE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Methyl 2-amino-5-bromobenzoate 52727-57-8
Price: US $1.10-9.90/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 100KG
Release date: 2025-08-20

Hebei Xinsheng New Material Technology Co., LTD.

Product: METHYL 2-AMINO-5-BROMOBENZOATE 52727-57-8
Price: US $35.00-25.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 Ton
Release date: 2023-11-07

Honest Joy Holdings Limited

Product: 2-Amino-5-bromobenzoic Acid Methyl Ester 52727-57-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.9%
Supply Ability: 100 tons
Release date: 2022-01-14

52727-57-8, METHYL 2-AMINO-5-BROMOBENZOATERelated Search:

2-Amino-4-methylbenzoic acid methyl ester METHYL 2-AMINO-3-TRIFLUOROMETHYLBENZOATE METHYL 2-BROMO-4,5-DIFLUOROBENZOATE Methyl 5-chloroanthranilate 6-Bromo-2-methyl-4H-3,1-benzoxazin-4-one Methyl 2-amino-3,5-dibromobenzoate 5-Bromoisatoic anhydride METHYL 2-AMINO-5-BROMOBENZOATE METHYL 2-ACETAMIDO-5-BROMOBENZOATE METHYL 2-AMINO-4-BROMOBENZOATE METHYL 4-AMINO-3-BROMOBENZOATE,Methyl 4-amino-3-bromobenzoate 98%,Methyl 4-amino-3-bromobenzoate, GC 98% Methyl benzoate 2-Amino-5-bromobenzoic acid 5-BROMO-2-NITRO-BENZOIC ACID METHYL ESTER 3-BROMO-5-METHOXY-2,6-DINITRO-BENZOIC ACID METHYL ESTER 6-BROMO-2-(2-METHYLPHENYL)-4H-3,1-BENZOXAZIN-4-ONE Methyl 3-Amino-5-bromobenzoate Methyl 3-amino-4-bromobenzoate

2-Amino-5-bromobenzoic acid methyl ester~5-Bromoanthranilic acid methyl ester

5-BROMOANTHRANILIC ACID METHYL ESTER 99+%

Methyl 2-amino-5-bromobenzoate,98%

2-Amino-5-BromoBenzoic Acid methyl ester Methyl 2-amino-5-bromobenzoate

4-Bromo-2-(methoxycarbonyl)aniline, Methyl 5-bromoanthranilate

2-Amino-5-bromobenzoic Acid Methyl Ester Methyl 2-Amino-5-bromobenzoate 5-Bromoanthranilic Acid Methyl Ester

Methyl 2-aMino-5-broMobenzoate 96%

METHYL 5-BROMOANTHRANILATE

METHYL 2-AMINO-5-BROMOBENZOATE

AURORA KA-6223

LABOTEST-BB LT00454801

2-AMINO-5-BROMOBENZOIC ACID METHYL ESTER

5-BROMOANTHRANILIC ACID METHYL ESTER

Methyl 5-Bromoanthranilate &gt

Benzoic acid, 2-amino-5-bromo-, methyl ester

5-BROMO METHYL ANTHRANILATE

52727-57-8

C8H8BrNO2

BrC6H3NH2CO2CH3

Esters

Organic Building Blocks

C8 to C9

Carbonyl Compounds

Building Blocks

amine | carboxylic ester| alkyl bromide

Anilines, Amides & Amines

Bromine Compounds

C8 to C9

Carbonyl Compounds

Esters

Benzoic acid

Acids & Esters

Aromatic Esters