ChemicalBook > CAS DataBase List > (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM

(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM

Product Name
(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM
CAS No.
301224-40-8
Chemical Name
(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM
Synonyms
HOVEYDA-GRUBBS;HOVEYDA-GRUBBS CATALYST;Hoveyda-Grubbs Catalyst 2nd;Hoveyda-Grubbs 2nd;Hoveyda-Grubbs Catalyst 2nd Generation;[1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(2-isopropoxyphenyl)methylene]ruthenium;NH22260;eneration;Hoveyda-g;yst 2nd g
CBNumber
CB0667713
Molecular Formula
C31H37Cl2N2ORu
Formula Weight
625.62
MOL File
301224-40-8.mol
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(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM Property

Melting point:
216-220 °C(lit.)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form 
Solid
color 
Green to Very Dark Green
Stability:
Hygroscopic
InChIKey
ZRPFJAPZDXQHSM-UHFFFAOYSA-L
SMILES
[Cl-][Ru+6]1(=[C-2]2N(C3C(=CC(C)=CC=3C)C)CCN2C2C(=CC(C)=CC=2C)C)(=[C-2]C2=CC=CC=C2O1C(C)C)[Cl-]
CAS DataBase Reference
301224-40-8
EPA Substance Registry System
Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-.kappa.O)phenyl]methylene-.kappa.C]-, (SP-5-41)- (301224-40-8)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H227Combustible liquid

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
569755
Product name
Hoveyda-Grubbs Catalyst 2nd Generation
Purity
97%
Packaging
2g
Price
$275
Updated
2025/07/31
Sigma-Aldrich
Product number
569755
Product name
Hoveyda-Grubbs Catalyst 2nd Generation
Purity
97%
Packaging
25g
Price
$1330
Updated
2025/07/31
Sigma-Aldrich
Product number
569755
Product name
Hoveyda-Grubbs Catalyst 2nd Generation
Purity
97%
Packaging
100mg
Price
$52
Updated
2025/07/31
Sigma-Aldrich
Product number
569755
Product name
Hoveyda-Grubbs Catalyst 2nd Generation
Purity
97%
Packaging
500mg
Price
$89
Updated
2025/07/31
Sigma-Aldrich
Product number
569755
Product name
Hoveyda-Grubbs Catalyst 2nd Generation
Purity
97%
Packaging
10g
Price
$639
Updated
2025/07/31
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(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM Chemical Properties,Usage,Production

Chemical Properties

Bright green crystalline powder

Uses

It′s a phosphine free version of Grubbs 2nd Generation Catalyst with comparable reactivity, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications.
It can be used as a catalyst for olefin cross-metathesis with fluorinated olefins (CM), ring-closing metathesis (RCM), ring-opening metathesis (ROM), and a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond.

reaction suitability

core: ruthenium
reagent type: catalyst
reaction type: Ring-Opening Polymerization

(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM Preparation Products And Raw materials

Raw materials

Preparation Products

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(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM Suppliers

China 173 India 1 Switzerland 1 United States 12 Global 187
xinxiang runyu material co.,Ltd
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15690792173
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0373-7759608
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sales@runvmat.com
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China
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Shanghai CoachChem Co., Ltd.
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+86-21-67299971；+86-21-67290723 18117322963
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021-67299972
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marketing@coachchem.com
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China
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Shanghai Tube Pharmaceutical Co., Ltd.
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021-54338626 18017892860
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021-54338626
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sales@tubepharm.com
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China
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ChemicalRIM Co., Ltd
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15184345951
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chemicalRIM@gmail.com
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China
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027-81388558 18963961905
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huahandingcheng@sina.com
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China
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Sinocompound Catalysts Co., Ltd.
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0512-67216630 67216634
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0512-56316689
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sales@sinocompound.com
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China
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KUNMING INSTITUTE OF PRECIOUS METALS
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18987894742
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kieran926@163.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
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market03@meryer.com
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China
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40228
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Beijing HwrkChemical Technology Co., Ltd
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18515581800 18501085097
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010-89508210
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sales.bj@hwrkchemical.com
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China
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9400
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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View Lastest Price from (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Hoveyda-Grubbs II 301224-40-8
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-27
XINXIANG RUNYU MATERIAL CO., LTD.
Product
Hoveyda-Grubbs catalyst 301224-40-8
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
100g
Release date
2025-04-25
Career Henan Chemical Co
Product
(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM 301224-40-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2018-08-13

301224-40-8, (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUMRelated Search:

Dicyclopentadiene 1,3-BIS(2,4,6-TRIMETHYLPHENYL)-IMIDAZOLIDINIUM-CHLORIDE Bis(triphenylphosphine)palladium(II) chloride Tetrakis(triphenylphosphine)palladium [1,1'-Bis(diphenylphosphino)ferrocene]dichloropalladium(II) 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex 1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride, Ruthenium(III) chloride hydrate (1,5-CYCLOOCTADIENE)(PYRIDINE)(TRICYCLOHEXYLPHOSPHINE)IRIDIUM(I) HEXAFLUOROPHOSPHATE DICHLORO-[1,3-BIS(DIISOPROPYLPHENYL)IMIDAZOLYLIDENE]-(3-CHLOROPYRIDYL)PALLADIUM(II) Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)bis(3-bromopyridine)ruthenium(II) DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II) Benzylidene-bis(tricyclohexylphosphine)dichlororuthenium GRUBBS CATALYST 2ND GENERATION Ruthenium (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM 1,3-Bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(i-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methyleneruthenium(II)dichloride RUTHENIUM, [1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO-[[2-ISOPROPOXY-5-(N-RESIN-LINKED AMINOSULFONYL)PHENYL]METHYLENE]

  • (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM
  • HOVEYDA-GRUBBS CATALYST
  • RUTHENIUM,[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE]
  • Hoveyda-Grubbs Catalyst 2nd Generation
  • Hoveyda-Grubbs Catalyst 2nd
  • [1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(2-isopropoxyphenylmethylene)ruthenium
  • Hoveyda-Grubbs Catalyst 2nd Generation,(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium
  • (1,3-Bis-(2,4,6-triMethylphenyl)-2-iMidazolidinylidene)dichloro (o-isopropylphenylMethylene)rutheniuM
  • (1,3-DiMesityliMidazolidin-2-ylidene)(2-isopropoxybenzylidene)rutheniuM(VI) chloride
  • NH22260
  • [1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(2-isopropoxyphenyl)methylene]ruthenium
  • Dichloro(1,3-diMesityl-2-iMidazolidinylidene)(2-isopropoxybenzylidene)rutheniuM
  • Hoveyda-Grubbs Catalyst 2nd Generation,97%
  • Hoveyda-Grubbs 2nd
  • Hoveyda-Grubbs Catalyst 2nd Generation 97%
  • HOVEYDA-GRUBBS
  • eneration
  • Hoveyda-g
  • rubbs CataL
  • yst 2nd g
  • Hoveyda-Grubbs Catalyst(TM) 2nd Generation
  • Hoveyda-Grubbs CataL
  • yst 2nd Generation
  • (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM ISO 9001：2015 REACH
  • Hoveyda-Grubbs G2
  • [1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(2-isopropoxybenzylidene)ruthenium(II)
  • Hoveyda-Grubbs Catalyst 3nd Generation
  • Dichloro(1,3-Dimesityl-2-imidazolidinylidene)(o-isopropoxyphenylmethylene)ruthenium
  • Hoveyda-Grubbs II
  • Hoveyda-Grubbs Catalyst<sup>?</sup> M720
  • Hoveyda-Grubbs Catalyst?M720
  • (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM
  • 301224-40-8
  • C31H38Cl2N2ORu
  • Catalysis and Inorganic Chemistry
  • Metathesis Catalysts
  • Ru