ChemicalBook > CAS DataBase List > Ticlopidine hydrochloride
Ticlopidine hydrochloride
- Product Name
- Ticlopidine hydrochloride
- CAS No.
- 53885-35-1
- Chemical Name
- Ticlopidine hydrochloride
- Synonyms
- Soper;tiklid;53-32c;4-c-32;ticlid;Tiklyd;ticlodix;Iparazin;panaldine;ticlodone
- CBNumber
- CB0674371
- Molecular Formula
- C14H14ClNS.ClH
- Formula Weight
- 300.25
- MOL File
- 53885-35-1.mol
More
Less
Ticlopidine hydrochloride Property
- Melting point:
- 205°C
- Density
- 1.37 g/cm3
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Sparingly soluble in water and in anhydrous ethanol, very slightly soluble in ethyl acetate.
- pka
- 7.64(at 25℃)
- form
- Solid
- color
- White
- Water Solubility
- Soluble to 100 mM in water and to 100 mM in DMSO.
- λmax
- 295nm(H2O)(lit.)
- Merck
- 14,9421
- InChI
- InChI=1S/C14H14ClNS.ClH/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14;/h1-4,6,8H,5,7,9-10H2;1H
- InChIKey
- MTKNGOHFNXIVOS-UHFFFAOYSA-N
- SMILES
- C12C=CSC=1CCN(CC1C=CC=CC=1Cl)C2.Cl
- CAS DataBase Reference
- 53885-35-1(CAS DataBase Reference)
More
Less
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 36-37/39-26
- WGK Germany
- 3
- RTECS
- XJ9089100
- HS Code
- 2934990002
- Toxicity
- LD50 in mice (mg/kg/24 hrs): 55 i.v.; >300 orally (Castaigne)
More
Less
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- T6654
- Product name
- Ticlopidine hydrochloride
- Purity
- analytical standard, for drug analysis
- Packaging
- 1g
- Price
- $40.2
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- T1423000
- Product name
- Ticlopidine hydrochloride
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 50 mg
- Price
- $118
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- PHR3367
- Product name
- Ticlopidine hydrochloride
- Purity
- certified reference material, pharmaceutical secondary standard
- Packaging
- 300MG
- Price
- $224
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 1667144
- Product name
- Ticlopidine hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 150mg
- Price
- $425
- Updated
- 2025/07/31
TCI Chemical
- Product number
- T3110
- Product name
- Ticlopidine Hydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $61
- Updated
- 2025/07/31
More
Less
Ticlopidine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Ticlid,Millot,France,1978
Uses
Ticlopidine hydrochloride is a selective P2Y12 receptor antagonist. It inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.
Uses
An antithrombotic. a platelet aggregation inhibitor
Uses
mucolytic, antibacterial, surface active agent
Manufacturing Process
A solution of thieno[3,2-c]pyridine (13.5 g; 0.1 mol) and 2-chlorobenzyl
chloride (17.7 g) in acetonitrile (150 ml) is boiled during 4 hours.
After evaporation of the solvent, the solid residue consists of 5-(2-
chlorobenzyl)-thieno[3,2-c]pyridinium chloride which melts at 166°C
(derivative n° 30). This compound is taken up into a solution comprising
ethanol (300 ml) and water (100 ml). Sodium borohydride (NaBH4)(20 g) is
added portionwise to the solution maintained at room temperature. The
reaction medium is maintained under constant stirring during 12 hours and is
then evaporated. The residue is taken up into water and made acidic with
concentrated hydrochloric acid to destroy the excess reducing agent. The
mixture is then made alkaline with ammonia and extracted with ether. The
ether solution is washed with water, dried and evaporated. The oily residue is
dissolved in isopropanol (50 ml) and hydrochloric acid in ethanol solution is
then added thereto.
After filtration and recrystallization from ethanol, there are obtained 5-(2-
chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride crystals
(yield: 60%) having a melting point (Koefler block) of 190°C.
Therapeutic Function
Platelet aggregation inhibitor
Biological Activity
Selective P2Y 12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo .
References
[1] Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 8, p. 1676 - 1678
[2] Patent: CN105461735, 2016, A. Location in patent: Paragraph 0020; 0021
[3] Patent: CN105541862, 2016, A. Location in patent: Paragraph 0015; 0019
Ticlopidine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Ticlopidine hydrochloride Suppliers
- Tel
- 0512-82780333-8506
- Fax
- 0512-82782911,82780556
- wangchunhua@homesunpharm.com
- Country
- China
- ProdList
- 57
- Advantage
- 50
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6003
- Advantage
- 61
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 18515581800 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 9400
- Advantage
- 55
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 15527768836
- 1791901229@qq.com
- Country
- China
- ProdList
- 6950
- Advantage
- 52
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- Fax
- 021-57711696
- marketing_china@spectrumchemical.com
- Country
- China
- ProdList
- 9658
- Advantage
- 60
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
- Country
- China
- ProdList
- 4747
- Advantage
- 58
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12335
- Advantage
- 58
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7552
- Advantage
- 61
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 020-39119399 18927568969
- Fax
- 020-39119999
- isunpharm@qq.com
- Country
- China
- ProdList
- 4720
- Advantage
- 55
- Tel
- 021-021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7783
- Advantage
- 58
- Tel
- 021-60549325 18616193163
- Fax
- 021-33250306
- Country
- China
- ProdList
- 4526
- Advantage
- 56
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9476
- Advantage
- 58
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 18333
- Advantage
- 56
- Tel
- 028-81700200 18116577057
- Fax
- 028-81705658
- 3003855609@qq.com
- Country
- China
- ProdList
- 7778
- Advantage
- 56
- Tel
- 400-8592883
- Fax
- 0731-82251112
- sales@huatengsci.com
- Country
- China
- ProdList
- 5872
- Advantage
- 58
- Tel
- 0512-87182056 18013166090
- Fax
- 0512-87182056
- lingling.qi@yacoo.com.cn
- Country
- China
- ProdList
- 6295
- Advantage
- 60
- Tel
- 027-59262863 13277907145 3091977954
- Fax
- 027-59420980
- Country
- China
- ProdList
- 4942
- Advantage
- 58
- Tel
- 0571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 14912
- Advantage
- 59
- Tel
- 027-59420981,18702770802
- Fax
- 027-83322098
- Country
- China
- ProdList
- 1975
- Advantage
- 50
- Tel
- 025-58849295 18951903616;
- Fax
- 025-68650336
- info@adooq.cn
- Country
- China
- ProdList
- 2990
- Advantage
- 60
- Tel
- 13621943973
- Fax
- -
- sales@shjiyipharmatech.com
- Country
- China
- ProdList
- 1166
- Advantage
- 55
- Tel
- +86 (21) 61124340
- Fax
- +86 (21) 6129-4103
- Country
- China
- ProdList
- 9756
- Advantage
- 58
- Tel
- 027-59599241 18871490274
- Fax
- 027-59599241
- 1400878000@qq.com
- Country
- China
- ProdList
- 9858
- Advantage
- 58
- Tel
- Fax
- -
- xg01_gj@163.com
- Country
- China
- ProdList
- 9484
- Advantage
- 50
- Tel
- 86(21)68097365
- Fax
- 86(21)33321566
- sales@anpharma.net
- Country
- China
- ProdList
- 4891
- Advantage
- 55
- Tel
- 027-59207879 1972026995 18140587686
- Fax
- QQ：1972026995
- sales@3600chem.com
- Country
- China
- ProdList
- 4447
- Advantage
- 55
- Tel
- 0512-63009836 18994340901
- Fax
- 0512-63006936
- helen@struchem.com
- Country
- China
- ProdList
- 3981
- Advantage
- 60
- Tel
- 551-65418679 15837135945
- Fax
- 0551-65418697
- info@tnjchem.com
- Country
- China
- ProdList
- 1889
- Advantage
- 62
- Tel
- 18620099427
- Fax
- +86-20-62619665
- amy@howeipharm.com
- Country
- China
- ProdList
- 6687
- Advantage
- 55
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- sales@chemwill.com
- Country
- China
- ProdList
- 1974
- Advantage
- 58
- Tel
- 0371-86658258
- Fax
- 0371-60996044
- info@coreychem.com
- Country
- China
- ProdList
- 10453
- Advantage
- 58
- Tel
- 020-61288194 61288195
- Fax
- 020-61288700
- 505721671@qq.com
- Country
- China
- ProdList
- 3866
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 86-21-50817262
- Fax
- 86-21-57712035
- sales@lancrix.com
- Country
- China
- ProdList
- 1502
- Advantage
- 55
- Tel
- 400-1166-196 15982826727
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 14603
- Advantage
- 60
- Tel
- 010-50973130 18101056239
- 3193328036@qq.com
- Country
- China
- ProdList
- 29760
- Advantage
- 68
- Tel
- 0751-2886750 13927877953
- Fax
- 0751-2886750
- 3005811397@qq.com
- Country
- China
- ProdList
- 13305
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- 0519-83246372 13585352506
- Fax
- 0519-83246372
- Country
- China
- ProdList
- 1844
- Advantage
- 58
More
Less
View Lastest Price from Ticlopidine hydrochloride manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Ticlopidine hydrochloride 53885-35-1
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500kg
- Release date
- 2021-09-22
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- Ticlopidine hydrochloride 53885-35-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-31
Henan Fengda Chemical Co., Ltd
- Product
- Ticlopidine hydrochloride 53885-35-1
- Price
- US $6.00-0.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-24
53885-35-1, Ticlopidine hydrochlorideRelated Search:
Hydrochlorothiazide
Topotecan hydrochloride
1-AdaMantanethylaMine
Pizotifen
Diphenhydramine Hydrochloride
Cephaloridine
Pyridine
TICLOPIDINE IMPURITY F
Ticlopidine IMpurity G
Benzenemethanamine, 2-chloro-N-(phenylmethylene)-, (E)- (9CI)
4-Oxo Ticlopidine
Ticlopidine IMpurity J
2-Chlorobenzylamine
N-(2-CHLOROBENZYL)-2-(2-THIENYL)ETHYLAMINE HYDROCHLORIDE
Ticlopidine IMpurity D
6.7-dihydrothieno[3.2.c]pyridin-4(5H)-one
Ticlopidine IMpurity E
thieno[3,2-c]pyridine