ChemicalBook > CAS DataBase List > 5-Bromo-4-chloro-3-indolyl-beta-D-glucoside

5-Bromo-4-chloro-3-indolyl-beta-D-glucoside

Product Name
5-Bromo-4-chloro-3-indolyl-beta-D-glucoside
CAS No.
15548-60-4
Chemical Name
5-Bromo-4-chloro-3-indolyl-beta-D-glucoside
Synonyms
X-GLC;X-GLU;GLUC(X-);X-GLUCOSIDE;X-BETA-D-GLC;X-BETA-D-GLUCOSIDE;X-Glc, X-glucoside;X-Gluc(5-Bromo-4-Chloro-3-Indolyl-;5-bromo-4-chloro-3-indoxylglucoside;5-Bromo-4-chloroindolylglucopyranoside
CBNumber
CB0683827
Molecular Formula
C14H15BrClNO6
Formula Weight
408.63
MOL File
15548-60-4.mol
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5-Bromo-4-chloro-3-indolyl-beta-D-glucoside Property

Melting point:
249-251 °C
alpha 
-81 º (c=1, DMF)
Boiling point:
673.9±55.0 °C(Predicted)
Density 
1.882±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF: 50 mg/mL, clear, colorless to very faintly yellow
pka
12.74±0.70(Predicted)
form 
Crystalline powder
color 
White to Light yellow
BRN 
1552603
InChI
InChI=1/C14H15BrClNO6/c15-5-1-2-6-9(10(5)16)7(3-17-6)22-14-13(21)12(20)11(19)8(4-18)23-14/h1-3,8,11-14,17-21H,4H2/t8-,11-,12+,13-,14-/s3
InChIKey
OPIFSICVWOWJMJ-OTXFOCTGSA-N
SMILES
C12C(Cl)=C(C=CC=1NC=C2O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)Br |&1:11,12,14,15,17,r|
CAS DataBase Reference
15548-60-4(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
8-10-21
HS Code 
29389090
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B4527
Product name
5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside
Purity
≥97%
Packaging
5mg
Price
$170
Updated
2026/03/19
Sigma-Aldrich
Product number
B4527
Product name
5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside
Purity
≥97%
Packaging
25mg
Price
$553
Updated
2026/03/19
TCI Chemical
Product number
B5393
Product name
5-Bromo-4-chloro-3-indolyl β-D-Glucopyranoside [for Biochemical Research]
Purity
>98.0%(HPLC)
Packaging
200mg
Price
$36
Updated
2026/03/19
TCI Chemical
Product number
B5393
Product name
5-Bromo-4-chloro-3-indolyl β-D-Glucopyranoside [for Biochemical Research]
Purity
>98.0%(HPLC)
Packaging
1g
Price
$100
Updated
2026/03/19
Sigma-Aldrich
Product number
B4527
Product name
5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside
Purity
≥97%
Packaging
100mg
Price
$1710
Updated
2026/03/19
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5-Bromo-4-chloro-3-indolyl-beta-D-glucoside Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

Substrate for beta-D-glucosidase

Definition

ChEBI: An indolyl carbohydrate that is the beta-D-glucoside of 3-hydroxy-1H-indole in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively. It is used to test for th presence of an enzyme, beta-glucosidase, which cleaves the glycosidic bond to give 5-bromo-4-chloro-3-hydroxy-1H-indole, which immediately dimerises to give an intensely blue product.

Synthesis

Method 1: Take 5-bromo-4-chloro-3-indolyl-2,3,4,6-tetra-O-acetyl--D-glucopyranoside dissolved in 15mL of methanol and cooled to 0 in an ice bath; then add 3mL (0.5 mol/L) of sodium methanol methanol solution dropwise and stirred for 5h at this temperature; at the end of the reaction, the reaction solution was poured into pre-treated cationic exchange resin (cationic). After the reaction, the reaction solution was poured into the pre-treated cation exchange resin (pretreatment method of the resin: firstly, rinse the resin with water; then soak it in 5% hydrochloric acid for about 4h, and wash it to neutral; then soak it in 5% sodium hydroxide solution for about 4h, and wash it to neutral; finally, soak it in 5% hydrochloric acid for 4h, and wash it to neutral), and then it was slowly stirred for 5-10min, and then filtered, and then rinsed by methanol, and then the filtrate was evaporated and removed the solvent, and it was obtained as 0.49g of white solid 5-bromo-4-chloro-3-beta-indolyl-beta-indoline-3-beta-indole. -indolyl-beta-D-glucopyranoside, yield 81.6%, melting point 86.5 .

Method 2: 40 mg of compound 5 was dissolved in 5 mL of methanol, cooled to 0 C in an ice bath, then 5 mL (0.2 mol/L) of methanol solution of sodium methanol was added dropwise and stirred for 3 h at this temperature; at the end of the reaction, the reaction solution was poured into pre-treated cation-exchange resin (pre-treatment method as in section 1.2.1) and stirred slowly for 5~10 min; filtered, rinsed with methanol, the filtrate was evaporated to remove the solvent to obtain 10mg of white solid, i.e., 5-bromo-4-chloro-3-indolyl-beta-D-glucopyranoside, with a yield of 40.3% and a melting point of 82.1C. The reaction was completed by pouring the reaction solution into the pre-treated cation exchange resin (pretreatment method as in section 1.2.1).

5-Bromo-4-chloro-3-indolyl-beta-D-glucoside Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-4-chloro-3-indolyl-beta-D-glucoside Suppliers

Shanghai Hanguang Biotechnology Co., LTD
Tel
13302171746 13302171746
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3488620832@qq.com
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China
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Feiyang Biotechnology Co., Ltd
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0533-7866336 13573361699
Fax
+86-533-7866337
Email
sales@chemfy.com
Country
China
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Shanghai JONLN Reagent Co., Ltd.
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400-0066400 13621662912
Fax
021-55660885
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422131432@qq.com
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China
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Guangzhou Yaoguang Technology Co., Ltd.
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13020159086
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yangjue@ygfuture.com
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China
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Jinan Shangbo Pharmaceutical Co., Ltd.
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18253163690
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yinxiuyang@shengquan.com
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China
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Shanghai ZymeTree Biotech Co.,Ltd.
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15300487802
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jlin@microbiosyn.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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future industrial shanghai co., ltd
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400-0066400 13621662912
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021-55660885
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sales@jonln.com
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China
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Beijing HwrkChemical Technology Co., Ltd
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89508211 18501085097
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010-89508210
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sales.bj@hwrkchemical.com
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China
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Adamas Reagent, Ltd.
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400-6009262 15618770481
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021-64823266
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yhx@titansci.com
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View Lastest Price from 5-Bromo-4-chloro-3-indolyl-beta-D-glucoside manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Bromo-4-chloro-3-indolyl-beta-D-glucoside 15548-60-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2026-01-27
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Bromo-4-chloro-3-indolyl-beta-D-glucoside 15548-60-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
5-Bromo-4-chloro-3-indolyl-beta-D-glucoside 15548-60-4
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-17

15548-60-4, 5-Bromo-4-chloro-3-indolyl-beta-D-glucosideRelated Search:


  • 5-BROMO-4-CHLORO-3-INDOLYL-BETA-D-GLUCOPYRANOSIDE (X-GLU)
  • 5-BROMO-4-CHLORO-3-INDOLYL-β-D-GLUCOPYRANOSIDE (X-GLC)
  • 5-BROMO-4-CHLORO-3-INDOLYL-b-D-GLUCO-PYRANOSIDE (X-GLU) extrapure
  • X-Glc, X-glucoside
  • (2S,3R,4S,5S,6R)-2-[(5-Bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • 4-Chloro-5-bromo-1H-indole-3-yl β-D-glucopyranoside
  • 5-Bromo-4-chloro-1H-indol-3-yl β-D-glucopyranoside
  • 5-Bromo-4-chloro-3-indolyl-beta-D-glucoside,98%
  • (2S,3R,4S,5S,6R)-2-((5-broMo-4-chloro-1H-indol-3-yl)oxy)-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol
  • 5-bromo-4-chloro-3-indolyl-glucopyranoside
  • GLUC(X-)
  • 5-BROMO-4-CHLORO-3-INDOXYL-BETA-D-GLUCOPYRANOSIDE
  • 5-BROMO-4-CHLORO-3-INDOLYL-BETA-D-GLUCOPYRANOSIDE
  • 5-BROMO-4-CHLORO-3-INDOLYL-BETA-D-GLUCOSIDE
  • 5-Bromo-4-chloro-3-indolyl-beta-D-glucopyranoside 98%
  • 5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside ,98%
  • 5-Bromo-4-chloro-3-indolyl β-D-Glucopyranoside [for Biochemical Research]
  • X-Glc(X-glucoside、5-Bromo-4-chloro-3-indolyl-β-D-glucopyranoside)
  • (2S,3R,4S,5S,6R)-2-[(5-Bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
  • 5-bromo-4-chloro-3-indolyl β-D-glucoside
  • X-BETA-D-GLUCOSIDE
  • X-BETA-D-GLC
  • X-GLC
  • X-GLU
  • X-GLUCOSIDE
  • 5-bromo-4-chloroindol-3-yl-beta-D-glucopyranoside
  • 5-BROMO-4-CHLORO-3-INDOLYLB-D-GLUCOPYRAN OSIDE
  • X-Gluc(5-Bromo-4-Chloro-3-Indolyl-
  • 5-bromo-4-chloro-3-indoxylglucoside
  • 5-Bromo-4-chloroindolylglucopyranoside
  • beta-d-glucopyranoside,5-bromo-4-chloro-1h-indol-3-yl
  • 5-BROMO-4-CHLORO-3-INDOLYL-β-D-GLUCOPYRANOSIDE (X-GLU)
  • β-D-Glucopyranoside, 5-bromo-4-chloro-1H-indol-3-yl
  • 5-Bromo-4-chloro-3-indolyl beta-D-Glucopyranoside [for Biochemical Research]
  • 5-Bromo-4-chloro-3-indolyl-β-D-glucopyranoside
  • 5-Bromo-4-chloro-3-(beta-D-glucopyranosyloxy)indole
  • 5-Bromo-4-chloro-3-indolyl-beta-D-glucoside USP/EP/BP
  • 5-bromo-4-chloro-3-indole- β- D-glucopyranoside
  • 5-bromo-4-chloro-3-indolyl-β-D-glucopyranoside,X-Glu
  • Bromo-4-Chloro-3-Indolyl-b-D-Glucopyranoside (X-Glu, X-Glc) for tissue culture, 99%
  • 5-Bromo-4-Chloro-3-Indolyl-β-D-Glucopyranoside (X-Glu, X-Glc) for molecular biology, 99%
  • 5-Bromo-4-chloro-3-indolyl-β-D-glucoside
  • 5-Bromo-4-chloro-3-(β-D-glucopyranosyloxy)indole
  • (5-bromo-4-chloroindol-3-yl) β-D-glucopyranoside
  • 5-Bromo-4-chloro-3-indolyl β-<sc>D</sc>-glucopyranoside
  • 15548-60-4
  • Plant Molecular Biology
  • Plant Biotechnology
  • Substrates, Stains and Detection Kits
  • Substrates by Enzyme
  • Enzymes, Inhibitors, and Substrates
  • Cloning
  • Enzyme Substrates
  • Glucosidase, beta-
  • Biochemicals and Reagents
  • BioChemical
  • substrate