3-Bromo-5-chlorobenzonitrile
- Product Name
- 3-Bromo-5-chlorobenzonitrile
- CAS No.
- 304854-55-5
- Chemical Name
- 3-Bromo-5-chlorobenzonitrile
- Synonyms
- CAS:304854-55-5;3-Bromo-5-chlorobenzoni;3-BroMo-5-chlorobenzonitile;3-chloro-5-bromobenzenitrile;3-BROMO-5-CHLOROBENZONITRILE;Benzonitrile, 3-bromo-5-chloro-;3-Bromo-5-chlorobenzonitrile >
- CBNumber
- CB0691598
- Molecular Formula
- C7H3BrClN
- Formula Weight
- 216.46
- MOL File
- 304854-55-5.mol
3-Bromo-5-chlorobenzonitrile Property
- Melting point:
- 70.7-71.1°C
- Boiling point:
- 144 °C / 12mmHg
- Density
- 1.74±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- color
- White to Almost white
- InChI
- InChI=1S/C7H3BrClN/c8-6-1-5(4-10)2-7(9)3-6/h1-3H
- InChIKey
- DRKWKPSNVQVDKZ-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC(Cl)=CC(Br)=C1
- CAS DataBase Reference
- 304854-55-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 20/21/22-36/37/38-22
- Safety Statements
- 26-36/37/39
- RIDADR
- 3439
- HazardClass
- IRRITANT
- PackingGroup
- III
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B3118
- Product name
- 3-Bromo-5-chlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- B3118
- Product name
- 3-Bromo-5-chlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $123
- Updated
- 2025/07/31
- Product number
- B683678
- Product name
- 3-Bromo-5-chlorobenzonitrile
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B683678
- Product name
- 3-Bromo-5-chlorobenzonitrile
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR11380
- Product name
- 3-Bromo-5-chlorobenzonitrile
- Packaging
- 10g
- Price
- $99
- Updated
- 2021/12/16
3-Bromo-5-chlorobenzonitrile Chemical Properties,Usage,Production
Uses
3-Bromo-5-chlorobenzonitrile is the intermediate that is used for the new type anticancer medicine, belongs to the fine-chemical intermediate technical field.
Synthesis
A solution of 1,3-dibromo-5-chlorobenzene (10 g, 37.34 mmol), pyridine (6.03 mL) and copper(I) cyanide (3.34 g, 37.34 ) in DMF (57.74 mL) was refluxed under nitrogen for 2 days. mmol) in DMF (57.74 mL) was refluxed under nitrogen for 2 days. The reaction was difficult to monitor by TLC and when impurities were observed, the reaction was cooled to room temperature. The reaction mixture was quenched with 40 mL of ether, the precipitate was filtered and washed with ether (20 mL x 2). The organic layer was washed with a mixture of water and concentrated ammonium hydroxide (2:1, 40 mL), saturated ammonium chloride solution (40 mL x 2) and saturated sodium bicarbonate solution (40 mL). . The organic layer was dried over anhydrous sodium sulfate and concentrated. The residue was purified by column chromatography to afford the compound 3-bromo-5-chlorobenzonitrile (2 g, 25%).
3-Bromo-5-chlorobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Bromo-5-chlorobenzonitrile manufacturers
- Product
- 3-Bromo-5-chlorobenzonitrile 304854-55-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-10
- Product
- 3-Bromo-5-chlorobenzonitrile 304854-55-5
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 3-Bromo-5-chlorobenzonitrile 304854-55-5
- Price
- US $35.00-25.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 Ton
- Release date
- 2023-11-08