ACETOACETYL COENZYME A SODIUM SALT

Product Name: ACETOACETYL COENZYME A SODIUM SALT
CAS No.: 102029-52-7
Chemical Name: ACETOACETYL COENZYME A SODIUM SALT
Synonyms: Acetyl-CoA oxidase;Acetoacetyl coenzyme A;ACETOACETYL COENZYME A SODIUM;ACETOACETYL COENZYME A SODIUM SALT;S-(3-oxobutanoate)-CoA,tetrasodiumsalt;ACETOACETYL COENZYME A TRISODIUM SALT &;Acetoacetyl coenzyme A hydrate sodium salt;Acetoacetyl coenzyme A trisodium salt tetrahydrate;Coenzyme A,S-(3-oxobutanoate), tetrasodium salt (9CI);coenzyme A acetoacetyl derivative trisodium salt hydrate
CBNumber: CB0692964
Molecular Formula: C25H37N7Na3O18P3S
Formula Weight: 917.55
MOL File: 102029-52-7.mol

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ACETOACETYL COENZYME A SODIUM SALT Property

storage temp.: −20°C
solubility: H₂O: 50 mg/mL, clear, colorless to faintly yellow

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Safety

WGK Germany: 3
F: 10-21

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 235095
Product name: Acetoacetyl Coenzyme A, Trisodium Salt Tetrahydrate
Packaging: 5mg
Price: $355
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NA47206
Product name: Acetoacetyl coenzyme A trisodium salt tetrahydrate
Packaging: 10mg
Price: $750
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: ENZ0008576
Product name: ACETOACETYL COENZYME A SODIUM SALT
Purity: 95.00%
Packaging: 5MG
Price: $859.62
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NA47206
Product name: Acetoacetyl coenzyme A trisodium salt tetrahydrate
Packaging: 50mg
Price: $2500
Updated: 2021/12/16

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ACETOACETYL COENZYME A SODIUM SALT Chemical Properties,Usage,Production

Uses

Acetoacetyl coenzyme A sodium is a central endogenous metabolite. The Km at pH 7.5 for Acetoacetyl coenzyme A sodium is 1.10 mM. Acetoacetyl coenzyme A sodium can be used for the synthesis of phosphotransbutyrylase (PTB) and poly-3-hydroxybutyrate (PHB)[1][2].

IC 50

Microbial Metabolite

Purification Methods

Purification can be carried out by passage through a DEAE-cellulose formate column, then through a Dowex 50 (H+) column to remove Na ions, concentrated by lyophilisation and redissolved in H2O. It is commercially available as a solution of 0.05g/mL of H2O. The concentration of acetoacetylcoenzyme A is determined by the method of Stern et al. [J Biol Chem 221 15 1956]. It is stable at pH 7-7.5 for several hours at 0o (half-life ca 1-2hours). At room temperature it is hydrolysed in ca 1-2hours at pH 7-7.5. At pH 1.0/20o it is more stable than at neutrality. A solution of the trisodium salt (0.05g/mL H2O) adjusted to pH 5 with 2N NaOH can be stored frozen for several weeks. It is stable at pH 2-3/-17o for at least 6 months. [Hersch & Jencks J Biol Chem 242 3468 1967, Clikenbeard et al. J Biol Chem 250 3108 1975, Simon & Shemin J Am Chem Soc 75 2520 1953, Moffatt & Khorana 81 1265 1959, Salem et al. Biochem J 258 563 1989, Beilstein 26 III/IV 3668.]

References

[1] Thompson DK, et al. Purification and properties of an acetoacetyl coenzyme A-reacting phosphotransbutyrylase from Clostridium beijerinckii ("Clostridium butylicum") NRRL B593. Appl Environ Microbiol. 1990 Mar;56(3):607-13. DOI:10.1128/aem.56.3.607-613.1990
[2] Chohan SN, et al. Acetoacetyl coenzyme A reductase and polyhydroxybutyrate synthesis in rhizobium (Cicer) sp. Strain CC 1192. Appl Environ Microbiol. 1998 Aug;64(8):2859-63. DOI:10.1128/AEM.64.8.2859-2863.1998

ACETOACETYL COENZYME A SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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ACETOACETYL COENZYME A SODIUM SALT Suppliers

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102029-52-7, ACETOACETYL COENZYME A SODIUM SALTRelated Search:

Citric acid Pyruvic acid Acetylcholine L-Tetrahydrofolic Acid Linoleic acid Acetyl coenzyme A sodium salt 4-Methylthio-2-butanone 2'-Deoxyadenosine-5'-diphosphate disodium salt 3'-PHOSPHOADENOSINE 5'-PHOSPHATE Adenosine-5'-diphosphate disodium salt 2'-DEOXYADENOSINE 3'-MONOPHOSPHATE SODIUM SALT ACETOACETYL COENZYME A SODIUM SALT ACETOACETYL COENZYME A SODIUM SALT HYDRATE ADENOSINE 5'-DIPHOSPHATE, MONOSODIUM SALT DIHYDRATE, 98 COENZYME A SODIUM SALT

Coenzyme A,S-(3-oxobutanoate), tetrasodium salt (9CI)

[5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[[3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[2-(3-oxobutanoylsulfanyl)ethylamino]propyl]amino]butoxy]-oxidophosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-yl] phosphate

ACETOACETYL COENZYME A TRISODIUM SALT &

ACETOACETYL COENZYME A SODIUM

Acetoacetyl coenzyme A

coenzyme A acetoacetyl derivative trisodium salt hydrate

Acetoacetyl coenzyme A hydrate sodium salt

Acetoacetyl coenzyme A sodium salt hydrate,Acetoacetyl-CoANa3

ACETOACETYL COENZYME A SODIUM SALT

Acetoacetyl coenzyme A trisodium salt tetrahydrate

Acetyl-CoA oxidase

risodium,[5-(6-aminopurin-9-yl)-4-hydroxy-2-[[[[3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[2-(3-oxobutanoylsulfanyl)ethylamino]propyl]amino]butoxy]-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]oxolan-3-yl]hydrogenphosphate

S-(3-oxobutanoate)-CoA,tetrasodiumsalt

102029-52-7

C25H37N7O18P3SNa3

C25H37N7Na3O18P3S1

C25H37N7Na3O18P3SH2O

C25H37N7O18P3S

C25H37N7Na3O18P3S4H2O

Biochemicals and Reagents

BioChemical

Coenzyme A and Derivatives

Metabolomics

Lipid Library

Metabolic Libraries

Nucleosides, Nucleotides, Oligonucleotides