Sodium dichloroacetate

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Sodium dichloroacetate

Uses

Product Name: Sodium dichloroacetate
CAS No.: 2156-56-1
Chemical Name: Sodium dichloroacetate
Synonyms: SDA;dichloroctansodny;erlcyiuanna;sodium dichloroacet;NATRIUMDICHLORACETAT;Sodiumdichloracetate;Dichloroacetate (DCA);SODIUM DICHLOROACETATE;Dichloroacetate Sodium;Sodium dichloroacetater
CBNumber: CB0695718
Molecular Formula: C2H3Cl2NaO2
Formula Weight: 152.93
MOL File: 2156-56-1.mol

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Sodium dichloroacetate Property

Melting point:: 198 °C (dec.) (lit.)
storage temp.: Inert atmosphere,2-8°C
solubility: Methanol (Slightly), Water (Slightly)
form: Powder
color: White
PH: 6.0 to 8.5(50g/L, 25 ℃)
Water Solubility: soluble in cold water
Sensitive: Moisture Sensitive
Stability:: Hygroscopic
InChIKey: LUPNKHXLFSSUGS-UHFFFAOYSA-M
CAS DataBase Reference: 2156-56-1(CAS DataBase Reference)
EPA Substance Registry System: Sodium dichloroacetate (2156-56-1)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-40
Safety Statements: 26-37/39-36-36/37
RIDADR: 2811
WGK Germany: 2
RTECS: AG9275000
HS Code: 29154000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 347795
Product name: Sodium dichloroacetate
Purity: 98%
Packaging: 10g
Price: $75.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 347795
Product name: Sodium dichloroacetate
Purity: 98%
Packaging: 50g
Price: $262
Updated: 2024/03/01

TCI Chemical

Product number: D1048
Product name: Sodium Dichloroacetate
Purity: >97.0%(T)
Packaging: 25g
Price: $76
Updated: 2024/03/01

TCI Chemical

Product number: D1719
Product name: Sodium Dichloroacetate
Purity: >99.0%(T)
Packaging: 10g
Price: $54
Updated: 2024/03/01

Alfa Aesar

Product number: B21827
Product name: Sodium dichloroacetate, 97%
Packaging: 10g
Price: $57.65
Updated: 2024/03/01

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Sodium dichloroacetate Chemical Properties,Usage,Production

Uses

Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD.

Chemical Properties

white powder

Uses

Treatment of neurologic injury (pyruvate dehydrogenase activator).

Uses

Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase.

brand name

Ceresine (Cypros).

General Description

Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity.

Biological Activity

Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo .

storage

Desiccate at RT

Sodium dichloroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sodium dichloroacetate manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Sodium Dichloroacetate 2156-56-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-04-30

Hangzhou Hyper Chemicals Limited

Product: Sodium dichloroacetate 2156-56-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5,000KG
Release date: 2024-04-26

Henan Fengda Chemical Co., Ltd

Product: Sodium dichloroacetate 2156-56-1
Price: US $8.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

2156-56-1, Sodium dichloroacetateRelated Search:

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Wholesale Price Sodium Dichloroacetate (DCA) CAS?2156-56-1?with High Quality in Stock

sodium dichloroacet

Dichloroacetate (DCA)

Sodium Dichloroacetate, ≥ 99.0%

2156-56-1

Cl2CHCO2Na

C2HCl2NaO2

C2HCl2O2Na

Inorganic Salts

Synthetic Reagents