Uses
ChemicalBook > CAS DataBase List > Sodium dichloroacetate

Sodium dichloroacetate

Uses
Product Name
Sodium dichloroacetate
CAS No.
2156-56-1
Chemical Name
Sodium dichloroacetate
Synonyms
SDA;dichloroctansodny;erlcyiuanna;sodium dichloroacet;NATRIUMDICHLORACETAT;Sodiumdichloracetate;Dichloroacetate (DCA);SODIUM DICHLOROACETATE;Dichloroacetate Sodium;Sodium dichloroacetater
CBNumber
CB0695718
Molecular Formula
C2H3Cl2NaO2
Formula Weight
152.93
MOL File
2156-56-1.mol
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Sodium dichloroacetate Property

Melting point:
198 °C (dec.) (lit.)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Powder
color 
White
PH
6.0 to 8.5(50g/L, 25 ℃)
Water Solubility 
soluble in cold water
Sensitive 
Moisture Sensitive
Stability:
Hygroscopic
InChIKey
LUPNKHXLFSSUGS-UHFFFAOYSA-M
CAS DataBase Reference
2156-56-1(CAS DataBase Reference)
EPA Substance Registry System
Sodium dichloroacetate (2156-56-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-37/39-36-36/37
RIDADR 
2811
WGK Germany 
2
RTECS 
AG9275000
HS Code 
29154000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
347795
Product name
Sodium dichloroacetate
Purity
98%
Packaging
10g
Price
$75.8
Updated
2024/03/01
Sigma-Aldrich
Product number
347795
Product name
Sodium dichloroacetate
Purity
98%
Packaging
50g
Price
$262
Updated
2024/03/01
TCI Chemical
Product number
D1048
Product name
Sodium Dichloroacetate
Purity
>97.0%(T)
Packaging
25g
Price
$76
Updated
2024/03/01
TCI Chemical
Product number
D1719
Product name
Sodium Dichloroacetate
Purity
>99.0%(T)
Packaging
10g
Price
$54
Updated
2024/03/01
Alfa Aesar
Product number
B21827
Product name
Sodium dichloroacetate, 97%
Packaging
10g
Price
$57.65
Updated
2024/03/01
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Sodium dichloroacetate Chemical Properties,Usage,Production

Uses

Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD.

Chemical Properties

white powder

Uses

Treatment of neurologic injury (pyruvate dehydrogenase activator).

Uses

Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase.

brand name

Ceresine (Cypros).

General Description

Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity.

Biological Activity

Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo .

storage

Desiccate at RT

Sodium dichloroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sodium dichloroacetate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Sodium dichloroacetate 2156-56-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Sodium Dichloroacetate 2156-56-1
Price
US $99.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-08
Hebei Mujin Biotechnology Co.,Ltd
Product
Sodium dichloroacetate 2156-56-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-04

2156-56-1, Sodium dichloroacetateRelated Search:

Dichloroacetic acid Sodium chloride Dichloroacetic acid methyl ester Trisodium phosphate Diclofenac sodium Sodium citrate Sodium benzoate Sodium acetate Sodium hydroxide Sodium chloroacetate Sodium bicarbonate Sodium chlorite Sodium diethyldithiocarbamate trihydrate Sodium dichloroisocyanurate Sodium dimethyl 5-sulphonatoisophthalate 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Chloroacetic acid SODIUM TRICHLOROACETATE

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