ChemicalBook > CAS DataBase List > Sodium dichloroacetate

Sodium dichloroacetate

Uses

Product Name: Sodium dichloroacetate
CAS No.: 2156-56-1
Chemical Name: Sodium dichloroacetate
Synonyms: SDA;dichloroctansodny;erlcyiuanna;sodium dichloroacet;NATRIUMDICHLORACETAT;Sodiumdichloracetate;Dichloroacetate (DCA);SODIUM DICHLOROACETATE;Dichloroacetate Sodium;Sodium dichloroacetater
CBNumber: CB0695718
Molecular Formula: C2H3Cl2NaO2
Formula Weight: 152.93
MOL File: 2156-56-1.mol

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Sodium dichloroacetate Property

Melting point:: 198 °C (dec.) (lit.)
storage temp.: Inert atmosphere,2-8°C
solubility: Methanol (Slightly), Water (Slightly)
form: Powder
color: White
PH: 6.0 to 8.5(50g/L, 25 ℃)
Water Solubility: soluble in cold water
Sensitive: Moisture Sensitive
Stability:: Hygroscopic
InChI: InChI=1S/C2H2Cl2O2.Na.H/c3-1(4)2(5)6;;/h1H,(H,5,6);;
InChIKey: LUPNKHXLFSSUGS-UHFFFAOYSA-M
SMILES: C(Cl)(Cl)C(=O)O.[NaH]
CAS DataBase Reference: 2156-56-1(CAS DataBase Reference)
EPA Substance Registry System: Sodium dichloroacetate (2156-56-1)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-40
Safety Statements: 26-37/39-36-36/37
RIDADR: 2811
WGK Germany: 2
RTECS: AG9275000
HS Code: 29154000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 347795
Product name: Sodium dichloroacetate
Purity: 98%
Packaging: 10g
Price: $78.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 347795
Product name: Sodium dichloroacetate
Purity: 98%
Packaging: 50g
Price: $270
Updated: 2025/07/31

TCI Chemical

Product number: D1048
Product name: Sodium Dichloroacetate
Purity: >97.0%(T)
Packaging: 25g
Price: $68
Updated: 2025/07/31

TCI Chemical

Product number: D1719
Product name: Sodium Dichloroacetate
Purity: >99.0%(T)
Packaging: 10g
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: D1719
Product name: Sodium Dichloroacetate
Purity: >99.0%(T)
Packaging: 25g
Price: $89
Updated: 2025/07/31

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Sodium dichloroacetate Chemical Properties,Usage,Production

Uses

Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD.

Chemical Properties

white powder

Uses

Treatment of neurologic injury (pyruvate dehydrogenase activator).

Uses

Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase.

brand name

Ceresine (Cypros).

General Description

Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity.

Biological Activity

Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo .

Synthesis

79-43-6

2156-56-1

General procedure for the synthesis of sodium dichloroacetate from dichloroacetic acid: Cl2CHCO2H (135 μL, 1.64 mmol) was dissolved in H2O (2 mL), treated with 1.00 M NaOH (1.60 mL, 1.60 mmol), and the reaction was stirred for 2 hours at room temperature. Upon completion of the reaction, the volatiles were removed under vacuum to give a pale yellow residue. The residue was suspended in acetone, the suspension was filtered, the resulting colorless solid was washed with acetone and finally dried under vacuum. Yield: 227 mg, 96% yield.

storage

Desiccate at RT

References

[1] Journal of Organometallic Chemistry, 2018, vol. 869, p. 201 - 211

Sodium dichloroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sodium dichloroacetate manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Sodium dichloroacetate 2156-56-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-12-08

Hebei Chuanghai Biotechnology Co., Ltd

Product: Sodium dichloroacetate 2156-56-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-28

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: Sodium dichloroacetate 2156-56-1
Price: US $100.00-75.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-21

2156-56-1, Sodium dichloroacetateRelated Search:

Dichloroacetic acid methyl ester Trisodium phosphate Sodium diethyldithiocarbamate trihydrate Dichloroacetic acid Sodium chloride Diclofenac sodium Sodium citrate Sodium benzoate Sodium acetate Sodium hydroxide Sodium chloroacetate Sodium bicarbonate Sodium chlorite Sodium dichloroisocyanurate Sodium dimethyl 5-sulphonatoisophthalate 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Chloroacetic acid SODIUM TRICHLOROACETATE

dichloroacetate,sodiumsalt

dichloro-aceticacisodiumsalt

dichloroctansodny

Sodiumdichloracetate

NATRIUMDICHLORACETAT

SDA

SODIUM DICHLOROACETATE

erlcyiuanna

Sodiumdichloroacetate(DCA)

DICHLOROACETIC ACID SODIUM SALT

Sodiumdichloroacetate,97%

SODIUM DICHLOROACETIC ACID

dlchloroacetic acid sodium salt

Dichloroacetate Sodium

Sodium 2,2-dichloroacetate

Sodium dichloroacetate,98%

Sodium dichloroacetate,Dichloroacetic acid sodium salt

sodiuM 2,2-dichloroacetic acid

Acetic acid,2,2-dichloro-, sodiuM salt (1:1)

SodiuM dichloroacetate 98%

Sodium Dichloroacetate &gt

Sodium dichloroacetater

Wholesale Price Sodium Dichloroacetate (DCA) CAS?2156-56-1?with High Quality in Stock

sodium dichloroacet

Dichloroacetate (DCA)

Sodium Dichloroacetate, ≥ 99.0%

Sodium dichloroacetate, 10 mM in DMSO

DCA (Sodium dichloroacetate)

2156-56-1

Cl2CHCO2Na

C2HCl2NaO2

C2HCl2O2Na

C2HNaCL2O2

Inorganic Salts

Synthetic Reagents