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Curcumol

Product Name
Curcumol
CAS No.
4871-97-0
Chemical Name
Curcumol
Synonyms
Curcumo;CURCUMOL;Curcumae;(-)-Curcumol;Curcumol USP/EP/BP;5,8-Epoxy-10(14)-guaien-8-ol;(3S,3aS,5S,6R,8aS)-5-Isopropyl-3-methyl-8-methyleneoctahydro-6H-3a,6-epoxyazulen-6-ol;(3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol;6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethyl)-, (3S,3aS,5S,6R,8aS)-;(3s-(3a,3aa,5a,6a,8ab))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6h-3a,6-epoxyazulen-6-ol
CBNumber
CB0701727
Molecular Formula
C15H24O2
Formula Weight
236.35
MOL File
4871-97-0.mol
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Curcumol Property

Melting point:
141.0 to 145.0 °C
Boiling point:
334.5±42.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO:55.67(Max Conc. mg/mL);235.54(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);84.62(Max Conc. mM)
Ethanol:28.5(Max Conc. mg/mL);120.58(Max Conc. mM)
pka
13.02±0.60(Predicted)
color 
White to Light yellow
InChIKey
QRMPRVXWPCLVNI-YYFQZIEXSA-N
LogP
3.276 (est)
CAS DataBase Reference
4871-97-0
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Safety

WGK Germany 
3
HS Code 
29321900
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
36236
Product name
( ?)-Curcumol
Purity
analytical standard
Packaging
10mg
Price
$269
Updated
2022/05/15
TCI Chemical
Product number
C3439
Product name
Curcumol
Purity
>98.0%(GC)
Packaging
10mg
Price
$133
Updated
2024/03/01
TCI Chemical
Product number
C3439
Product name
Curcumol
Purity
>98.0%(GC)
Packaging
50mg
Price
$401
Updated
2024/03/01
Cayman Chemical
Product number
26849
Product name
Curcumol
Packaging
50mg
Price
$596
Updated
2024/03/01
Cayman Chemical
Product number
26849
Product name
Curcumol
Packaging
100mg
Price
$954
Updated
2024/03/01
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Curcumol Chemical Properties,Usage,Production

Definition

ChEBI: Curcumol is a sesquiterpenoid.

Biological Activity

Curcumol is a biologically active sesquiterpene with many pharmacological activities such as anticancer, antimicrobial, antifungal, antiviral and anti-inflammatory. It efficiently induces apoptosis in many cancer cells by targeting key signaling pathways such as MAPK/ERK, PI3K/Akt and NF-κB, which are often dysregulated in several cancers.

in vitro

Curcumol ((-)-Curcumol) is the major component extracted from root of Rhizoma Curcumae . Curcumol exerts anticancer effect in cholangiocarcinoma cells via down-regulating CDKL3. It induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway. It suppresses breast cancer cell metastasis by inhibiting MMP-9 via JNK1/2 and Akt-dependent NF-κB signaling pathways.

Curcumol Preparation Products And Raw materials

Raw materials

Preparation Products

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Curcumol Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from Curcumol manufacturers

Hebei Duling International Trade Co. LTD
Product
Curcumol 4871-97-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2022-10-17
Shanghai Standard Technology Co., Ltd.
Product
Curcumol 4871-97-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-01-19
Career Henan Chemical Co
Product
Curcumol 4871-97-0
Price
US $1.00/KG
Min. Order
1KG
Purity
40%-99%
Supply Ability
1000kg
Release date
2018-08-20

4871-97-0, CurcumolRelated Search:


  • 6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethyl)-, (3S,3aS,5S,6R,8aS)-
  • (3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol
  • CURCUMOL
  • (3s-(3a,3aa,5a,6a,8ab))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6h-3a,6-epoxyazulen-6-ol
  • 5,8-Epoxy-10(14)-guaien-8-ol
  • (3S-(3alpha,3Aalpha,5alpha,6alpha,8abeta))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3A,6-epoxyazulen-6-ol
  • Curcumae
  • Curcumol USP/EP/BP
  • Curcumo
  • (-)-Curcumol
  • (3S,3aS,5S,6R,8aS)-5-Isopropyl-3-methyl-8-methyleneoctahydro-6H-3a,6-epoxyazulen-6-ol
  • 4871-97-0
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