THIP HYDROCHLORIDE

Product Name: THIP HYDROCHLORIDE
CAS No.: 64603-91-4
Chemical Name: THIP HYDROCHLORIDE
Synonyms: THPO;THIP;gaboxadol;Lu 02-030;Gaboxadolum;Gaboxadol-d4;Einecs 264-963-0;THIP HYDROCHLORIDE;Gaboxadolum [latin];4,5,6,7-Tetrahydroisoxazole(5,4-C)pyridin-3-ol
CBNumber: CB0712787
Molecular Formula: C6H8N2O2
Formula Weight: 140.14
MOL File: 64603-91-4.mol

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THIP HYDROCHLORIDE Property

Melting point:: 242-244° (dec)
Density: 1.36±0.1 g/cm3(Predicted)
storage temp.: Store at RT
solubility: ethanol: 0.91 mg/mL
pka: pKa (water, 25°): 4.44 ±0.03; 8.48 ±0.04
form: solid
color: white
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: NY3396800

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 0807
Product name: THIPhydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $162
Updated: 2021/12/16

Usbiological

Product number: 256926
Product name: THIP hydrochloride
Packaging: 50mg
Price: $403
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0001097
Product name: GABOXADOL
Purity: 95.00%
Packaging: 50MG
Price: $685.21
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb528193
Product name: THPO
Packaging: 10μg
Price: $290.7
Updated: 2021/12/16

ChemScene

Product number: CS-0002507
Product name: THIP
Purity: 99.36%
Packaging: 25mg
Price: $90
Updated: 2021/12/16

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THIP HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Gaboxadol HCl (64603-91-4) is a GABA-A receptor agonist. Hypnotic agent.

Uses

GABAa agonist, GABAc antagonist

Definition

ChEBI: 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol is an oxazole.

Biological Activity

Systemically active GABA A receptor agonist and GABA C receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats.

References

1) Meera et al. (2011), Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors; J. Neurophysiol., 106 2057

THIP HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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THIP HYDROCHLORIDE Suppliers

China 69 Germany 2 Switzerland 1 United Kingdom 2 United States 11 USA 1 Global 86

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View Lastest Price from THIP HYDROCHLORIDE manufacturers

Dorne Chemical Technology co. LTD

Product: THIP HYDROCHLORIDE 64603-91-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2024-03-26

Zhengzhou Anbu Chem Co.,Ltd

Product: THIP HYDROCHLORIDE 64603-91-4
Price: US $7.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KGS
Release date: 2023-11-23

Shandong Hanjiang Chemical Co., Ltd

Product: THIP HYDROCHLORIDE 64603-91-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10T
Release date: 2024-01-25

64603-91-4, THIP HYDROCHLORIDERelated Search:

EFAROXAN HYDROCHLORIDE Tamoxifen citrate CYCLOPAMINE 1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID Sodium carboxymethyl cellulose Trazodone Paroxetine Gabapentin THIP HYDROCHLORIDE Isoxazole C-ISOXAZOL-5-YL-METHYLAMINE HYDROCHLORIDE 5-Methylisoxazole MUSCIMOL 2-ISOXAZOL-4-YL-ETHYLAMINE ISOXAZOL-5-YLMETHYL-METHYL-AMINE GABOXADOL HYDROCHLORIDE C-ISOXAZOL-5-YL-METHYLAMINE 4,5-dimethylisoxazole

THIP HYDROCHLORIDE

4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3(2h)-onehydrate

4-c)pyridin-3(2h)-one,4,5,6,7-tetrahydro-isoxazolo(hydrate

gaboxadol

4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL

4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HYDROCHLORIDE

4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one

THIP

THPO

4,5,6,7-Tetrahydroisoxazole(5,4-C)pyridin-3-ol

Einecs 264-963-0

Gaboxadolum

Gaboxadolum [latin]

Isoxazolo(5,4-C)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-

Lu 02-030

4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one hydrochloride

Recombinant Mouse Thrombopoietin/Tpo/Thpo Protein, His Tag

Gaboxadol-d4

neurons,GABA Receptor,γ-Aminobutyric acid Receptor,IPSCs,THIP,Gamma-aminobutyric acid Receptor,inhibit,sleep disorders,Inhibitor

64603-91-4

BioChemical

Cell Signaling and Neuroscience

Cell Biology

GABA and Glycine Receptor Modulators

Ligand-Gated Ion Channels

Ion Channels

GABA/Glycine receptor