Synthesis
ChemicalBook > CAS DataBase List > 2,4-Difluoronitrobenzene

2,4-Difluoronitrobenzene

Synthesis
Product Name
2,4-Difluoronitrobenzene
CAS No.
446-35-5
Chemical Name
2,4-Difluoronitrobenzene
Synonyms
2,4-DIFLUORO-1-NITROBENZENE;2.4 DFNB;2,4-Difluoronitroben;3,5-diflurobenzonitrile;2,4-Difluronitrobenzene;2,4-Difluoronitribenzene;2,4-DIFLUORO NITROBENZEN;2,4-DIFLUORONITROBENZENE;Flurbiprofen Impurity 24;1,3-Difluor-4-nitrobenzol
CBNumber
CB0722917
Molecular Formula
C6H3F2NO2
Formula Weight
159.09
MOL File
446-35-5.mol
More
Less

2,4-Difluoronitrobenzene Property

Melting point:
9-10 °C (lit.)
Boiling point:
203-204 °C (lit.)
Density 
1.451 g/mL at 25 °C (lit.)
vapor density 
>1 (vs air)
refractive index 
n20/D 1.511(lit.)
Flash point:
195 °F
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Light yellow to Brown
Specific Gravity
1.45
Water Solubility 
Insoluble in water.
BRN 
2048034
Stability:
Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
InChIKey
RJXOVESYJFXCGI-UHFFFAOYSA-N
CAS DataBase Reference
446-35-5(CAS DataBase Reference)
NIST Chemistry Reference
2,4-Difluoronitrobenzene(446-35-5)
EPA Substance Registry System
2,4-Difluoronitrobenzene (446-35-5)
More
Less

Safety

Hazard Codes 
T,Xi,Xn
Risk Statements 
25-36/37/38-23/24/25-20/21/22
Safety Statements 
26-45-36/37/39-23
RIDADR 
UN 2810 6.1/PG 1
WGK Germany 
3
RTECS 
CZ5730000
Hazard Note 
Irritant
TSCA 
T
HazardClass 
6.1
PackingGroup 
III
HS Code 
29049090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
233226
Product name
2,4-Difluoronitrobenzene
Purity
99%
Packaging
25g
Price
$20.16
Updated
2024/03/01
Sigma-Aldrich
Product number
233226
Product name
2,4-Difluoronitrobenzene
Purity
99%
Packaging
100g
Price
$73.8
Updated
2024/03/01
TCI Chemical
Product number
D1636
Product name
2,4-Difluoronitrobenzene
Purity
>99.0%(GC)
Packaging
25g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
D1636
Product name
2,4-Difluoronitrobenzene
Purity
>99.0%(GC)
Packaging
500g
Price
$126
Updated
2024/03/01
Alfa Aesar
Product number
A13249
Product name
2,4-Difluoro-1-nitrobenzene, 98%
Packaging
25g
Price
$30.65
Updated
2024/03/01
More
Less

2,4-Difluoronitrobenzene Chemical Properties,Usage,Production

Synthesis

KF with n-Hexadecyltrimethylammonium bromide as the PTC has been shown recently to work in dimethylformamide (DMF), important owing to the low cost16 of DMF.

Chemical Properties

yellow liquid

Uses

2,4-Difluoronitrobenzene has been used in the synthesis of: 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction; (±)-horsfiline; resin-bound 2-arylaminobenzimidazoles.
2,?4-?Difluoronitrobenzene is a reactant in the preparation of 4-?thiazolidinone derivatives as antimicrobial agents.

Uses

2,4-Difluoronitrobenzene has been used in the synthesis of 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction, (±)-horsfiline and resin-bound-2-arylaminobenzimidazoles.

Uses

2,4-Difluoronitrobenzene has been used in the synthesis of:

  • 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction
  • (±)-horsfiline
  • resin-bound 2-arylaminobenzimidazoles

General Description

Nucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module.

2,4-Difluoronitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,4-Difluoronitrobenzene Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
More
Less

View Lastest Price from 2,4-Difluoronitrobenzene manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
2,4-Difluoronitrobenzene 446-35-5
Price
US $10.00/kg
Min. Order
1kg
Purity
99.6%
Supply Ability
100000
Release date
2024-04-25
Henan Fengda Chemical Co., Ltd
Product
2,4-Difluoronitrobenzene 446-35-5
Price
US $9.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-23
Hebei Guanlang Biotechnology Co,.LTD
Product
2,4-Difluoronitrobenzene 446-35-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2023-07-03

446-35-5, 2,4-DifluoronitrobenzeneRelated Search:


  • 1,3-difluoro-4-nitrobenzene
  • 1-Nitro-2,4-difluorobenzene
  • 2,4-difluoro-1-nitro-benzen
  • 2,4-Difluronitrobenzene
  • Benzene, 2,4-difluoro-1-nitro-
  • 2,4-DIFLUORO-1-NITROBENZENE
  • 2,4-DIFLUORONITROBENZENE
  • 2,4-DIFLUORO NITROBENZEN
  • 2,4-Difluoronitribenzene
  • Benzene, 2,4-difluoro-1-nitro- (6CI,7CI,8CI,9CI)
  • 3,5-diflurobenzonitrile
  • 2,4-DIFLUORONITROBENZENE =99%(HPLC)
  • 2,4-Difluoronitroben
  • 2.4 DFNB
  • 2,4-Difluoronitrobenzene14
  • 2, 4-2 fluoro nitrobenzene
  • 2,4-Difluoronitrobenzene99%
  • 1,3-Difluor-4-nitrobenzol
  • 2,4-Difluoronitrobenzene&gt
  • 2,4-Difluoronitrobenzene,>98%
  • Flurbiprofen Impurity 24
  • 2,4-Difluoronitrobenzene ISO 9001:2015 REACH
  • 4-flouro-3-nitrobenzene sulfonic acid potassium salt
  • high quality 2,4-Difluoronitrobenzene
  • 2,4-Difluoronitrobenzene extrapure, 99%
  • 446-35-5
  • F2C6H3NO2
  • Building Blocks
  • Nitro Compounds
  • Organic Building Blocks
  • Nitrogen Compounds
  • Fluorine series
  • alkyl Fluorine| nitro-compound
  • HALIDE
  • Aromatic Hydrocarbons (substituted) & Derivatives