1-Methyl-3-nitro-1-nitrosoguanidine

Product Name: 1-Methyl-3-nitro-1-nitrosoguanidine
CAS No.: 70-25-7
Chemical Name: 1-Methyl-3-nitro-1-nitrosoguanidine
Synonyms: MNNG;MNG;Methylnitronitrosoguanidine;1-methyl-3-nitro-1-nitroso-guanidin;N-METHYL-N'-NITRO-N-NITROSOGUANIDINE;NA 1325;nsc9369;NSC 9369;nci-c01423;rcrawastenumberu163
CBNumber: CB0730037
Molecular Formula: C2H5N5O3
Formula Weight: 147.09
MOL File: 70-25-7.mol

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1-Methyl-3-nitro-1-nitrosoguanidine Property

Melting point:: 118°C (dec.)
Boiling point:: 267.16°C (rough estimate)
Density: 1.7979 (rough estimate)
refractive index: 1.6410 (estimate)
storage temp.: 0-6°C
solubility: almost transparency in hot Methanol
form: powder to crystal
pka: 3.09±0.50(Predicted)
color: Light yellow to Brown
Water Solubility: Reacts violently
Merck: 14,6103
Stability:: Unstable. Reacts violently with water. May detonate under impact. Heat, light and moisture sensitive. May explode if stored in sealed ampules. Highly flammable. Incompatible with aqueous solutions, acids, bases, oxidizing agents, reducing agents. Alkaline hydrolysis releases toxic and explosive gases.
InChIKey: VZUNGTLZRAYYDE-UHFFFAOYSA-N
CAS DataBase Reference: 70-25-7(CAS DataBase Reference)
NIST Chemistry Reference: Guanidine, n-methyl-n'-nitro-n-nitroso-(70-25-7)
IARC: 2A (Vol. 4, Sup 7) 1987
EPA Substance Registry System: N-Methyl-N'-nitro-N-nitrosoguanidine (70-25-7)

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Safety

Hazard Codes: T;N,N,T
Risk Statements: 45-20-36/38-51/53
Safety Statements: 53-45-61
RIDADR: 2926
RTECS: MF4200000
HS Code: 2925.29.9000
HazardClass: 4.1
PackingGroup: II
Hazardous Substances Data: 70-25-7(Hazardous Substances Data)
Toxicity: LD50 oral in rat: 90mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H350May cause cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: M0527
Product name: 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis)
Purity: >95.0%(T)
Packaging: 5g
Price: $89
Updated: 2021/12/16

TCI Chemical

Product number: M0527
Product name: 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis)
Purity: >95.0%(T)
Packaging: 25g
Price: $313
Updated: 2021/12/16

TRC

Product number: N493990
Product name: N’-Nitro-N-nitroso-N-methylguanidine(StabilizedwithWater)
Packaging: 100mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0003097
Product name: N-METHYL-N'-NITRO-N-NITROSOGUANIDINE
Purity: 95.00%
Packaging: 100MG
Price: $721.88
Updated: 2021/12/16

Matrix Scientific

Product number: 168011
Product name: 1-Methyl-3-nitro-1-nitrosoguanidine
Packaging: 25g
Price: $792
Updated: 2021/12/16

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1-Methyl-3-nitro-1-nitrosoguanidine Chemical Properties,Usage,Production

Chemical Properties

yellow to pink crystals

Uses

A DNA-damaging agent, used as a positive control in SHE cell transformation assays.

Uses

Experimentally as carcinogen and mutagen. Formerly in preparation of diazomethane.

Definition

ChEBI: An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position

Production Methods

MNNG is one of the first chemical mutagens and is a stabilized form of methylnitrosoguanidine, which has not been isolated. It does not occur in nature, and human exposure to it is limited to laboratories.

General Description

A yellow powder. Melting point 244°F. Decomposes above 212°F. A suspected carcinogen. Extremely hazardous as a mutagen. Avoid skin contact and inhalation of of vapors. Usually stored frozen (below 32°F) in polyethylene bottles that are tightly closed and contained in a metal can. May decomposed during prolonged storage and develop sufficient pressure in a closed container to explode. Keep away from heat, sparks, and open flame.

Air & Water Reactions

Highly flammable. Reacts violently with water .

Reactivity Profile

1-Methyl-3-nitro-1-nitrosoguanidine will detonate under high impact. 1-Methyl-3-nitro-1-nitrosoguanidine is sensitive to heat. A sample has exploded when melted in a sealed capillary tube. Incompatible with acids, bases, oxidizing agents and reducing agents. Reacts with bases to release highly toxic, irritating and explosive gases. Reacts slowly with acids to release nitrous acid. Reacts with various nucleophiles, especially amines and thiols. Reacts with aqueous potassium hydroxide to form a highly reactive compound. The crude product from aqueous nitrosation is pyrophoric but recrystallized material is stable .

Health Hazard

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. An explosive sensitive to heat or impact. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits very toxic fumes of NOx.

Carcinogenicity

N-Methyl-N-nitro-N-nitrosoguanidine (MNNG) is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

1-Methyl-3-nitro-1-nitrosoguanidine Preparation Products And Raw materials

Raw materials

Nitroguanidine Ethanol Methylamine Sodium nitrite 2-Methyl-2-thiopseudourea sulfate 1-Methyl-3-nitroguanidine Nitric acid Methanol 1-Butanol Cyanamide Sulfuric acid

Preparation Products

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1-Methyl-3-nitro-1-nitrosoguanidine Suppliers

Canada 1 China 132 France 1 Germany 3 India 6 Japan 6 Switzerland 1 United Kingdom 5 United States 18 Global 173

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Japan

Tel: --
Fax: --
Email: @TCIchemicals.com
Country: Japan
ProdList: 2741
Advantage: 58

Kanto Chemical Co., Inc.

Tel: --
Fax: --
Email: reag-info@gms.kanto.co.jp
Country: Japan
ProdList: 6756
Advantage: 74

Wako Pure Chemical Industries, Ltd.

Tel: --
Fax: --
Email: labchem-tec@wako-chem.co.jp
Country: Japan
ProdList: 6819
Advantage: 80

Nacalai Tesque, Inc.

Tel: --
Fax: --
Email: info-tech@nacalai.co.jp
Country: Japan
ProdList: 6046
Advantage: 75

Junsei Chemical Co., Ltd.

Tel: --
Fax: --
Email: shiyaku@junsei.co.jp
Country: Japan
ProdList: 3096
Advantage: 46

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View Lastest Price from 1-Methyl-3-nitro-1-nitrosoguanidine manufacturers

Wuhan Monad Medicine Tech Co.,LTD

Product: 1-Methyl-3-nitro-1-nitrosoguanidine 70-25-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.99%
Supply Ability: 20 tons/month
Release date: 2021-04-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Methyl-3-nitro-1-nitrosoguanidine 70-25-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 1-Methyl-3-nitro-1-nitrosoguanidine 70-25-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

70-25-7, 1-Methyl-3-nitro-1-nitrosoguanidineRelated Search:

6-Methyl-1,3,5-triazine-2,4-diamine Methylparaben Nitroguanidine Methyl salicylate Methyl acrylate Tribenuron methyl NITROSOGUANIDINE Methanol Tetramethylguanidine Diazomethane Basic Violet 1 Kresoxim-methyl METSULFURON METHYL Methyl nitrotoluene AZINPHOS-METHYL 1-BUTYL-3-NITRO-1-NITROSOGUANIDINE N'-NITRO-N-NITROSO-N-PROPYLGUANIDINE

1-methyl-3-nitro-1-nitroso-guanidin

1-nitroso-3-nitro-1-methylguanidine

Guanidine, 1-methyl-3-nitro-1-nitroso-

Methylnitronitrosoguanidine

MNG

mnng(n-methyl-n’-nitro-n-nitrosoguanidine

n’-nitro-n-nitroso-n-methylguanidine

NA 1325

nci-c01423

N-Methyl-N',2-dioxohydrazinecarboximidohydrazide 2-oxide

n-methyl-n’-nitro-n-nitroso-guanidin

N-Methyl-N-nitrosonitroguanidin

n-methylo-n’-nitro-n-nitrozoguanidyny(polish)

N-Methyl-N'-nitro-N-nitrosoguanidine (wetted with ca. 50% Water, containing 5g on a dry weight basis)

Guanidine, N-methyl-N-nitro-N-nitroso-

NMETHYLNNITRONITROSOGUANIDINE

1-METHYL-3-NITRO-NITROSOGUANIDINE

METHYL-N-NITRO-N-NITROSOGUANIDINE

NITROSOMETHYLNITROGUANIDINE

METHYLNITROSONITROGUANIDINE

NITROSO-NITRO-METHYLGUANIDINE

N-METHYL-N''-NITRO-N-NITROSOGUANIDINE , WETTED WITH 50% WATER

1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water)

Diazomethane precursor, MNNG, N-Methyl-Nμ-nitro-N-nitrosoguanidine

1-Methyl-2-nitro-1-nitrosoguanidine

3-Methyl-1-nitro-3-nitrosoguanidine

1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis)

1-METHYL-3-NITRO-1-NITROSOGUANIDINE

1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water, containing 5g on a dry weight basis)

N-METHYL-n,n'-NITROSOGUANIDINE

N-Methyl-N'-nitro-N-nitrosoguanidine ,97%

N-METHYL-N'-NITRO-N-NITROSOGUANIDINE, MO ISTENED WITH WATER

(wetted with ca. 50% Water, containing 5g on a dry weight basis)

1-Methyl-3-nitro-1-nitrosoguanidine&nbsp

1-Methyl-1-Nitroso-3-nitroguanidine

n-metylo-n’-nitro-n-nitrozoguanidyny

n-metylo-n’-nitro-n-nitrozoguanidyny(polish)

N-Metylo-N'-nitro-N-nitrozoguanidyny

N'-Nitro-N-nitroso-N-methylguanidine

n-nitroso-n’-nitro-n-methylguanidine

N-Nitroso-N-methylnitroguanidine

NSC 9369

nsc9369

Rcra waste number U163

rcrawastenumberu163

DIAZOMETHANE PRECURSOR

MNNG

N-METHYL-N'-NITRO-N-NITROSOGUANIDINE

N-METHYL-N-NITROSO-N'-NITROGUANIDINE

1-METHYL-3-NITRO-1-NITROSOGUANIDINE, MOISTENED WITH WATER

N-Methyl-N′-nitro-N-nitrosoguanidine (wetted with ca. 50% water)

N-Methyl-N'-nitro-N-nitrosoguanidine@100 μg/mL in Toluene

1-Methyl-3-nitro-1-nitrosoguanidine(wettedwithca.50%Water,containing5gonadryweightbasis)&gt

N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water)

1-METHYL-3-NITRO-1-NITROSOGUANIDINE (~50% WATER W/W. UNIT WEIGHT ON DRY BASIS)

1-Methyl-3-nitro-1-nitrosouanidine

N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) (1.0 mg/mL in Methanol)

N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with 40% Water)