ChemicalBook > CAS DataBase List > 2-Methyl-2-thiopseudourea sulfate

2-Methyl-2-thiopseudourea sulfate

Product Name
2-Methyl-2-thiopseudourea sulfate
CAS No.
867-44-7
Chemical Name
2-Methyl-2-thiopseudourea sulfate
Synonyms
S-MethyliSothourea Sulfate;S-Methyl isothiourea sulfate;methylsulfanylmethanimidamide;s-methylthiouroniumsulfate(2:1);methylcarbamimidothioate sulfate;S-Methyl-ITU;S-METHYLTHIOUREA;S-EIT hemihydrate;isothiouronium suL;2-Methyl-2-thiopseud
CBNumber
CB7105816
Molecular Formula
C2H8N2O4S2
Formula Weight
188.23
MOL File
867-44-7.mol
More
Less

2-Methyl-2-thiopseudourea sulfate Property

Melting point:
240-241 °C (dec.)(lit.)
Density 
1.28
Flash point:
3℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 0.1 g/mL, clear, colorless
pka
pK1:9.83(＋1) (25°C)
form 
Crystals or Crystalline Powder
color 
White
PH
5.5 (260g/l, H2O, 20℃)
Water Solubility 
260 g/L (20 ºC)
Sensitive 
Hygroscopic
BRN 
3917217
Stability:
Stable. Incompatible with strong oxidizing agents.
InChI
1S/2C2H6N2S.H2O4S/c2*1-5-2(3)4;1-5(2,3)4/h2*1H3,(H3,3,4);(H2,1,2,3,4)
InChIKey
BZZXQZOBAUXLHZ-UHFFFAOYSA-N
SMILES
CSC(N)=N.CSC(N)=N.OS(O)(=O)=O
CAS DataBase Reference
867-44-7(CAS DataBase Reference)
EPA Substance Registry System
Carbamimidothioic acid, methyl ester, sulfate (2:1) (867-44-7)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
UM9200000
TSCA 
TSCA listed
HS Code 
29309070
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M84445
Product name
S-Methylisothiourea hemisulfate salt
Purity
98%
Packaging
100g
Price
$35.4
Updated
2025/07/31
Sigma-Aldrich
Product number
M84445
Product name
S-Methylisothiourea hemisulfate salt
Purity
98%
Packaging
500g
Price
$62.37
Updated
2025/07/31
TCI Chemical
Product number
M0442
Product name
S-Methylisothiourea Sulfate
Purity
>98.0%(T)
Packaging
25g
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
M0442
Product name
S-Methylisothiourea Sulfate
Purity
>98.0%(T)
Packaging
100g
Price
$34
Updated
2025/07/31
Cayman Chemical
Product number
81300
Product name
S-methyl Isothiourea (hemisulfate)
Purity
≥98%
Packaging
1g
Price
$26
Updated
2024/03/01
More
Less

2-Methyl-2-thiopseudourea sulfate Chemical Properties,Usage,Production

Description

SMIT is a potent non-selective inhibitor of NOS isoforms in vitro but may lack good in vivo efficacy due to poor cellular penetration. The Ki values are 120, 200, and 160 nM using purified human iNOS, eNOS, and nNOS, respectively.

Chemical Properties

white crystalline powder

Uses

Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.

Biochem/physiol Actions

More potent than NMMA as an inhibitor of inducible nitric oxide synthetase (iNOS).

References

[1] E. P. GARVEY. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas.[J]. The Journal of Biological Chemistry, 1994, 50 1: 26669-26676. DOI: 10.1016/s0021-9258(18)47071-8

2-Methyl-2-thiopseudourea sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

5-[2-(METHYLTHIO)PYRIMIDIN-4-YL]THIOPHENE-2-SULFONYL CHLORIDE 5-CHLORO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-Methoxy-6-methyl-2-(methylthio)pyrimidine 4-METHYL-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 1-Methyl-3-nitro-1-nitrosoguanidine ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate 2-(METHYLTHIO)ETHANOL 5-METHYL-2-METHYLSULFANYL-PYRIMIDINE S-Methylisothiourea sulfate Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 5-BROMO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-MORPHOLINECARBOXAMIDINE 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid 5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-D]pyrimidine ,97% 5-CHLORO-2-METHOXYPYRIMIDINE-4-CARBOXYLIC ACID Aminoguanidine bicarbonate Gabexate mesylate METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 ETHYL 2-(ETHYLTHIO)-4-HYDROXYPYRIMIDINE-5-CARBOXYLATE 5-Chloro-2-(methylsulfonyl)pyrimidine 2-(METHYLTHIO)-4-(TRIFLUOROMETHYL)PYRIMIDINE 5-methoxy-2-(methylthio)pyrimidin-4-ol ,97% 4-Methoxy-6-methyl-2-(methylsulfonyl)pyrimidine ,97% 1,1-DIMETHYLGUANIDINE SULFATE 3-OXO-3-THIOPHEN-2-YL-PROPIONIC ACID ETHYL ESTER 4-AMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID 4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97% 4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97% 1-(4-METHYL-2-(METHYLTHIO)PYRIMIDIN-5-YL)ETHANONE 4-Chloro-6-methyl-2-(methylthio)pyrimidine 2-(METHYLSULFANYL)-5-PHENYLPYRIMIDINE 5-Methyl-2-(methylsulfonyl)pyrimidine ,97% 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER IMINOCTADINE TRIACETATE 6-Methyl-2-(methylthio)pyrimidin-4-ol ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE 5-AMINOPYRIMIDINE 5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid Aminoguanidinium sulphate
More
Less

2-Methyl-2-thiopseudourea sulfate Suppliers

Americas 1 Belgium 2 China 372 Europe 4 Finland 1 Germany 8 India 21 Japan 4 Russia 1 Slovakia 1 Switzerland 3 United Kingdom 16 United States 41 Global 475
Zhaoyuan Chaoda Chemical Ltd.
Tel
13964589815; 13964589815
Email
phx8415088@163.com
Country
China
ProdList
8
Advantage
58
Jinan Londi Medical Technology Co., LTD
Tel
0531-88996911 15628983711
Fax
0531-88996911
Email
3305202763@qq.com
Country
China
ProdList
125
Advantage
58
Shandong Chengwu Zeda General Chemical Co., Ltd.
Tel
0530-8865559
Fax
+0571-87984136
Email
zhedapanaco02@zhedachem.com
Country
China
ProdList
171
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9411
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44802
Advantage
61
More
Less

View Lastest Price from 2-Methyl-2-thiopseudourea sulfate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98.5%min
Supply Ability
1000kg
Release date
2021-08-16
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-13
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01

867-44-7, 2-Methyl-2-thiopseudourea sulfateRelated Search:

Ferrous sulfate monohydrate Atropine sulfate Potassium sulfate Copper(II) sulfate Tetramethylthiourea Neomycin sulfate Magnesium sulfate Colistin sulfate Ammonium sulfate Ferric sulfate Magnesium sulfate heptahydrate Albuterol sulfate Chloromethyl isopropyl carbonate Isobutyl methacrylate Sulfamethoxazole SODIUM SULFATE Ferrous sulfate 2-Methyl-4-isothiazolin-3-one

  • s-methylthiouroniumsulfate(2:1)
  • S-METHYL-ISO-THIOUREA
  • S-MethyliSothourea Sulfate
  • S-METHYLISOTHIOUREA HEMISULFATE NITRIC O XIDE SYNTHASE
  • S-Methylthioureasulfate=2-Methyl-2-thiopseudoureasulfate
  • 2-Methyl-2-thiopseudourea sulphate
  • S-EIT hemihydrate
  • S-Methylisothiouroniumsulfate,98%
  • 5-METHYLISOTHIOUREAHEMISULFATE
  • METHYLTHIOURONIUMSULPHATE
  • METHYLTHIURONIUMSULPHATE
  • 2-methyl-2-thio-pseudoure sulfate
  • methylcarbamimidothioate sulfate
  • methylsulfanylmethanimidamide
  • 2-METHYL-2-THIOSEUDOUREA SULFATE
  • S-METHYLTHIOUREA
  • Methyl carbaMiMidothioate bis(sulfate)
  • Methyl isothiourea disulfate
  • S-METHYLTHIOURONIUM SULFATE FOR SYNTHESI
  • CarbaMiMidothioic acid Methyl ester,sulphate salt forM.
  • S-Methyl-isothiouroniuM HeMisulfate
  • S-Methylisothiourea heMisulfate salt 98%
  • S-MethylisothiouroniuM sulfate, 98+%, 98+%
  • <i>S</i>-Methylisothiourea sulfate
  • S-Methylthiouronium sulfate for synthesis
  • 2-methyl-2-thio-pseudouresulfate(2:1)
  • 2-METHYL-2-THIOPSEUDOUREA SULFATE (S-METHYLISOTHIOUREA SULFATE)
  • carbamimidothioicacid,methylester,sulfate(2:1)
  • methylcarbamimidothioatesulfate(2:1)
  • Methylisothioureahydrogensulfate
  • s-methylisothioureasulfate(2:1)
  • 2-Methyl-2-thiopseudourea sulfate
  • Bis(2-methylisothiouronium) sulphate
  • Bis(2-methylthiouronium) sulphate
  • S-Methyl isothiourea sulfate
  • S-methyl isothiourea sultate
  • 2-Methyl-2-thiopseudourea hemisulfate salt, S-Methyl-ITU, S-Methylthiuronium sulfate, SMT
  • Bis(S-methyl isothiourea) sulfate
  • 2-Methyl-2-thiopseudourea hemisulfate,98%
  • 2-Methyl-2-thiopseud
  • Methyl imidothiocarbamate sulfate
  • Methyl carbamimidothioate hemisulphate
  • S-Methyl-2-isothiourea hemisulphate
  • 2-Methyl-2-thiopseudourea heMisulfate, 98% 100GR
  • 2-Methyl-2-thiopseudourea heMisulfate, 98% 500GR
  • 2-Methyl-2-thiopseudourea heMisulfate, 98% 5GR
  • S-Methyl-ITU
  • [amino-(methylthio)methylidene]ammonium
  • isothiouronium suL
  • S-MethylisothioureaSulfate&gt
  • 2-Methyl-2-thiopseudourea hemisulfate hemihydrate
  • 2-Methyl-2-thiopseudourea sulfate ISO 9001：2015 REACH
  • S-Methylisothiourea sulfate(2:1)or(2-methyl-2-thiopseudourea sulfate)
  • S-Methylthioureasulfat
  • s-Methylthiuronium sulphate, 98%
  • 2-Methyl-2-Thiopseudourea
  • 2-methylisothiourea sulfuric acid
  • <i>S</i>-Methylisothiourea hemisulfate salt