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2-Methyl-2-thiopseudourea sulfate

Product Name
2-Methyl-2-thiopseudourea sulfate
CAS No.
867-44-7
Chemical Name
2-Methyl-2-thiopseudourea sulfate
Synonyms
S-MethyliSothourea Sulfate;S-Methyl isothiourea sulfate;methylsulfanylmethanimidamide;s-methylthiouroniumsulfate(2:1);methylcarbamimidothioate sulfate;S-Methyl-ITU;S-METHYLTHIOUREA;S-EIT hemihydrate;isothiouronium suL;2-Methyl-2-thiopseud
CBNumber
CB7105816
Molecular Formula
C2H8N2O4S2
Formula Weight
188.23
MOL File
867-44-7.mol
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2-Methyl-2-thiopseudourea sulfate Property

Melting point:
240-241 °C (dec.)(lit.)
Density 
1.28
Flash point:
3℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 0.1 g/mL, clear, colorless
pka
pK1:9.83(＋1) (25°C)
form 
Crystals or Crystalline Powder
color 
White
PH
5.5 (260g/l, H2O, 20℃)
Water Solubility 
260 g/L (20 ºC)
Sensitive 
Hygroscopic
BRN 
3917217
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
867-44-7(CAS DataBase Reference)
EPA Substance Registry System
Carbamimidothioic acid, methyl ester, sulfate (2:1) (867-44-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
UM9200000
TSCA 
Yes
HS Code 
29309070
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M84445
Product name
S-Methylisothiourea hemisulfate salt
Purity
98%
Packaging
100g
Price
$34.3
Updated
2024/03/01
Sigma-Aldrich
Product number
M84445
Product name
S-Methylisothiourea hemisulfate salt
Purity
98%
Packaging
500g
Price
$86.4
Updated
2024/03/01
TCI Chemical
Product number
M0442
Product name
S-Methylisothiourea Sulfate
Purity
>98.0%(T)
Packaging
25g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
M0442
Product name
S-Methylisothiourea Sulfate
Purity
>98.0%(T)
Packaging
100g
Price
$34
Updated
2024/03/01
Alfa Aesar
Product number
A11044
Product name
S-Methylisothiouronium sulfate, 98+%
Packaging
100g
Price
$23.65
Updated
2024/03/01
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2-Methyl-2-thiopseudourea sulfate Chemical Properties,Usage,Production

Description

SMIT is a potent non-selective inhibitor of NOS isoforms in vitro but may lack good in vivo efficacy due to poor cellular penetration. The Ki values are 120, 200, and 160 nM using purified human iNOS, eNOS, and nNOS, respectively.

Chemical Properties

white crystalline powder

Uses

Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.

Biochem/physiol Actions

More potent than NMMA as an inhibitor of inducible nitric oxide synthetase (iNOS).

2-Methyl-2-thiopseudourea sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

5-[2-(METHYLTHIO)PYRIMIDIN-4-YL]THIOPHENE-2-SULFONYL CHLORIDE 5-CHLORO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-Methoxy-6-methyl-2-(methylthio)pyrimidine 4-METHYL-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 1-Methyl-3-nitro-1-nitrosoguanidine ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate 2-(METHYLTHIO)ETHANOL 5-METHYL-2-METHYLSULFANYL-PYRIMIDINE S-Methylisothiourea sulfate Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 5-BROMO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-MORPHOLINECARBOXAMIDINE 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid 5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-D]pyrimidine ,97% 5-CHLORO-2-METHOXYPYRIMIDINE-4-CARBOXYLIC ACID Aminoguanidine bicarbonate Gabexate mesylate METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 ETHYL 2-(ETHYLTHIO)-4-HYDROXYPYRIMIDINE-5-CARBOXYLATE 5-Chloro-2-(methylsulfonyl)pyrimidine 2-(METHYLTHIO)-4-(TRIFLUOROMETHYL)PYRIMIDINE 5-methoxy-2-(methylthio)pyrimidin-4-ol ,97% 4-Methoxy-6-methyl-2-(methylsulfonyl)pyrimidine ,97% 1,1-DIMETHYLGUANIDINE SULFATE 3-OXO-3-THIOPHEN-2-YL-PROPIONIC ACID ETHYL ESTER 4-AMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID 4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97% 4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97% 1-(4-METHYL-2-(METHYLTHIO)PYRIMIDIN-5-YL)ETHANONE 4-Chloro-6-methyl-2-(methylthio)pyrimidine 2-(METHYLSULFANYL)-5-PHENYLPYRIMIDINE 5-Methyl-2-(methylsulfonyl)pyrimidine ,97% 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER IMINOCTADINE TRIACETATE 6-Methyl-2-(methylthio)pyrimidin-4-ol ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE 5-AMINOPYRIMIDINE 5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid Aminoguanidinium sulphate
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2-Methyl-2-thiopseudourea sulfate Suppliers

Americas 1 Belgium 2 China 347 Europe 4 Finland 1 Germany 8 India 21 Japan 4 Russia 1 Slovakia 1 Switzerland 3 United Kingdom 16 United States 41 Global 450
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View Lastest Price from 2-Methyl-2-thiopseudourea sulfate manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-01
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98.5%min
Supply Ability
1000kg
Release date
2021-08-16
Hangzhou ICH Biofarm Co., Ltd
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98.0% min
Supply Ability
10tons/month
Release date
2023-06-09

867-44-7, 2-Methyl-2-thiopseudourea sulfateRelated Search:

Ferrous sulfate monohydrate Atropine sulfate Potassium sulfate Copper(II) sulfate Tetramethylthiourea Neomycin sulfate FERROUS SULFATE Magnesium sulfate Colistin sulfate Ammonium sulfate Ferric sulfate Magnesium sulfate heptahydrate Albuterol sulfate Chloromethyl isopropyl carbonate Isobutyl methacrylate SODIUM SULFATE Sulfamethoxazole 2-Methyl-4-isothiazolin-3-one

  • s-methylthiouroniumsulfate(2:1)
  • S-METHYL-ISO-THIOUREA
  • S-MethyliSothourea Sulfate
  • S-METHYLISOTHIOUREA HEMISULFATE NITRIC O XIDE SYNTHASE
  • S-Methylthioureasulfate=2-Methyl-2-thiopseudoureasulfate
  • 2-Methyl-2-thiopseudourea sulphate
  • S-EIT hemihydrate
  • S-Methylisothiouroniumsulfate,98%
  • 5-METHYLISOTHIOUREAHEMISULFATE
  • METHYLTHIOURONIUMSULPHATE
  • METHYLTHIURONIUMSULPHATE
  • 2-methyl-2-thio-pseudoure sulfate
  • methylcarbamimidothioate sulfate
  • methylsulfanylmethanimidamide
  • 2-METHYL-2-THIOSEUDOUREA SULFATE
  • S-METHYLTHIOUREA
  • Methyl carbaMiMidothioate bis(sulfate)
  • Methyl isothiourea disulfate
  • S-METHYLTHIOURONIUM SULFATE FOR SYNTHESI
  • CarbaMiMidothioic acid Methyl ester,sulphate salt forM.
  • S-Methyl-isothiouroniuM HeMisulfate
  • S-Methylisothiourea heMisulfate salt 98%
  • S-MethylisothiouroniuM sulfate, 98+%, 98+%
  • <i>S</i>-Methylisothiourea sulfate
  • S-Methylthiouronium sulfate for synthesis
  • 2-methyl-2-thio-pseudouresulfate(2:1)
  • 2-METHYL-2-THIOPSEUDOUREA SULFATE (S-METHYLISOTHIOUREA SULFATE)
  • carbamimidothioicacid,methylester,sulfate(2:1)
  • methylcarbamimidothioatesulfate(2:1)
  • Methylisothioureahydrogensulfate
  • s-methylisothioureasulfate(2:1)
  • 2-Methyl-2-thiopseudourea sulfate
  • Bis(2-methylisothiouronium) sulphate
  • Bis(2-methylthiouronium) sulphate
  • S-Methyl isothiourea sulfate
  • S-methyl isothiourea sultate
  • 2-Methyl-2-thiopseudourea hemisulfate salt, S-Methyl-ITU, S-Methylthiuronium sulfate, SMT
  • Bis(S-methyl isothiourea) sulfate
  • 2-Methyl-2-thiopseudourea hemisulfate,98%
  • 2-Methyl-2-thiopseud
  • Methyl imidothiocarbamate sulfate
  • Methyl carbamimidothioate hemisulphate
  • S-Methyl-2-isothiourea hemisulphate
  • 2-Methyl-2-thiopseudourea heMisulfate, 98% 100GR
  • 2-Methyl-2-thiopseudourea heMisulfate, 98% 500GR
  • 2-Methyl-2-thiopseudourea heMisulfate, 98% 5GR
  • S-Methyl-ITU
  • (2260-00-6) 2-methyl-2-thiopseudourea sulfate
  • [amino-(methylthio)methylidene]ammonium
  • isothiouronium suL
  • S-MethylisothioureaSulfate&gt
  • 2-Methyl-2-thiopseudourea hemisulfate hemihydrate
  • 2-Methyl-2-thiopseudourea sulfate ISO 9001：2015 REACH
  • S-Methylisothiourea sulfate(2:1)or(2-methyl-2-thiopseudourea sulfate)
  • S-Methylthioureasulfat
  • s-Methylthiuronium sulphate, 98%
  • 2-Methyl-2-Thiopseudourea
  • 2-methylisothiourea sulfuric acid