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2-Methyl-2-thiopseudourea sulfate

Product Name
2-Methyl-2-thiopseudourea sulfate
CAS No.
867-44-7
Chemical Name
2-Methyl-2-thiopseudourea sulfate
Synonyms
S-MethyliSothourea Sulfate;S-Methyl isothiourea sulfate;methylsulfanylmethanimidamide;s-methylthiouroniumsulfate(2:1);methylcarbamimidothioate sulfate;S-Methyl-ITU;S-METHYLTHIOUREA;S-EIT hemihydrate;isothiouronium suL;2-Methyl-2-thiopseud
CBNumber
CB7105816
Molecular Formula
C2H8N2O4S2
Formula Weight
188.23
MOL File
867-44-7.mol
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2-Methyl-2-thiopseudourea sulfate Property

Melting point:
240-241 °C (dec.)(lit.)
Density 
1.28
Flash point:
3℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 0.1 g/mL, clear, colorless
pka
pK1:9.83(+1) (25°C)
form 
Crystals or Crystalline Powder
color 
White
PH
5.5 (260g/l, H2O, 20℃)
Water Solubility 
260 g/L (20 ºC)
Sensitive 
Hygroscopic
BRN 
3917217
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
867-44-7(CAS DataBase Reference)
EPA Substance Registry System
Carbamimidothioic acid, methyl ester, sulfate (2:1) (867-44-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
UM9200000
TSCA 
Yes
HS Code 
29309070
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M84445
Product name
S-Methylisothiourea hemisulfate salt
Purity
98%
Packaging
100g
Price
$34.3
Updated
2024/03/01
Sigma-Aldrich
Product number
M84445
Product name
S-Methylisothiourea hemisulfate salt
Purity
98%
Packaging
500g
Price
$86.4
Updated
2024/03/01
TCI Chemical
Product number
M0442
Product name
S-Methylisothiourea Sulfate
Purity
>98.0%(T)
Packaging
25g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
M0442
Product name
S-Methylisothiourea Sulfate
Purity
>98.0%(T)
Packaging
100g
Price
$34
Updated
2024/03/01
Alfa Aesar
Product number
A11044
Product name
S-Methylisothiouronium sulfate, 98+%
Packaging
100g
Price
$23.65
Updated
2024/03/01
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2-Methyl-2-thiopseudourea sulfate Chemical Properties,Usage,Production

Description

SMIT is a potent non-selective inhibitor of NOS isoforms in vitro but may lack good in vivo efficacy due to poor cellular penetration. The Ki values are 120, 200, and 160 nM using purified human iNOS, eNOS, and nNOS, respectively.

Chemical Properties

white crystalline powder

Uses

Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.

Biochem/physiol Actions

More potent than NMMA as an inhibitor of inducible nitric oxide synthetase (iNOS).

2-Methyl-2-thiopseudourea sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

5-[2-(METHYLTHIO)PYRIMIDIN-4-YL]THIOPHENE-2-SULFONYL CHLORIDE 5-CHLORO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-Methoxy-6-methyl-2-(methylthio)pyrimidine 4-METHYL-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 1-Methyl-3-nitro-1-nitrosoguanidine ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate 2-(METHYLTHIO)ETHANOL 5-METHYL-2-METHYLSULFANYL-PYRIMIDINE S-Methylisothiourea sulfate Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 5-BROMO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-MORPHOLINECARBOXAMIDINE 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid 5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-D]pyrimidine ,97% 5-CHLORO-2-METHOXYPYRIMIDINE-4-CARBOXYLIC ACID Aminoguanidine bicarbonate Gabexate mesylate METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 ETHYL 2-(ETHYLTHIO)-4-HYDROXYPYRIMIDINE-5-CARBOXYLATE 5-Chloro-2-(methylsulfonyl)pyrimidine 2-(METHYLTHIO)-4-(TRIFLUOROMETHYL)PYRIMIDINE 5-methoxy-2-(methylthio)pyrimidin-4-ol ,97% 4-Methoxy-6-methyl-2-(methylsulfonyl)pyrimidine ,97% 1,1-DIMETHYLGUANIDINE SULFATE 3-OXO-3-THIOPHEN-2-YL-PROPIONIC ACID ETHYL ESTER 4-AMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID 4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97% 4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97% 1-(4-METHYL-2-(METHYLTHIO)PYRIMIDIN-5-YL)ETHANONE 4-Chloro-6-methyl-2-(methylthio)pyrimidine 2-(METHYLSULFANYL)-5-PHENYLPYRIMIDINE 5-Methyl-2-(methylsulfonyl)pyrimidine ,97% 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER IMINOCTADINE TRIACETATE 6-Methyl-2-(methylthio)pyrimidin-4-ol ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE 5-AMINOPYRIMIDINE 5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid Aminoguanidinium sulphate
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2-Methyl-2-thiopseudourea sulfate Suppliers

Zhaoyuan Chaoda Chemical Ltd.
Tel
13964589815; 13964589815
Email
phx8415088@163.com
Country
China
ProdList
7
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58
Jinan Londi Medical Technology Co., LTD
Tel
0531-88996911 15628983711
Fax
0531-88996911
Email
3305202763@qq.com
Country
China
ProdList
125
Advantage
58
Zheda Panaco Chemical Engineering Co., Ltd
Tel
0571-86770761 13805730994;
Fax
+0571-87984136
Email
zhedapanaco02@zhedachem.com
Country
China
ProdList
100
Advantage
60
Zheda Panaco (Shandong) Chemical Enginering Co., Ltd.
Tel
0530-8865559 13805730994;
Fax
0530-8850005
Email
panaco@zhedachem.com
Country
China
ProdList
172
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 2-Methyl-2-thiopseudourea sulfate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98.5%min
Supply Ability
1000kg
Release date
2021-08-16
Hebei Weibang Biotechnology Co., Ltd
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-13
Hebei Weibang Biotechnology Co., Ltd
Product
2-Methyl-2-thiopseudourea sulfate 867-44-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01

867-44-7, 2-Methyl-2-thiopseudourea sulfateRelated Search:


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