Indications and Usage Toxicity
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Crospovidone

Indications and Usage Toxicity
Product Name
Crospovidone
CAS No.
25249-54-1
Chemical Name
Crospovidone
Synonyms
PVP;PVPP;POP;PVP K-30;POLYVINYLPYRROLIDONE K 90;POLYVINYLPOLYPYRROLIDONE;Polyplasdone;K-30;PLASDONE;POLYVIDONE
CBNumber
CB0744957
Molecular Formula
C6H9NO
Formula Weight
111.14176
MOL File
25249-54-1.mol
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Crospovidone Property

Melting point:
~165 °C (dec.)(lit.)
form 
powder
color 
White to off-white
Water Solubility 
Insoluble in water, acid and alkaline.
InChI
InChI=1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
InChIKey
WHNWPMSKXPGLAX-UHFFFAOYSA-N
SMILES
N1(C=C)CCCC1=O
CAS DataBase Reference
25249-54-1
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Safety

Safety Statements 
22-24/25
WGK Germany 
1
RTECS 
TR8370000
HS Code 
39059900
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
773417
Product name
Poly(vinyl pyrrolidone), cyanomethyl diphenylcarbamodithioate
Purity
average Mn 6,000, PDI ≤1.2
Packaging
1g
Price
$183
Updated
2023/01/07
Alfa Aesar
Product number
041631
Product name
Polyvinylpyrrolidone, cross linked
Packaging
100g
Price
$55.1
Updated
2024/03/01
Alfa Aesar
Product number
041631
Product name
Polyvinylpyrrolidone, cross linked
Packaging
500g
Price
$196
Updated
2024/03/01
Chem-Impex
Product number
33085
Product name
Poly(vinylpolypyrrolidone),<=50&igrave;mparticlesize.,meetsUSPspecifications
Purity
meetsUSPspecifications
Packaging
2.5KG
Price
$235.2
Updated
2021/12/16
Chem-Impex
Product number
33085
Product name
Poly(vinylpolypyrrolidone),<=50&igrave;mparticlesize.,meetsUSPspecifications
Purity
meetsUSPspecifications
Packaging
5KG
Price
$403.2
Updated
2021/12/16
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Crospovidone Chemical Properties,Usage,Production

Indications and Usage

Polyvinylpyrrolidone (PVP) is a polymer of vinyl pyrrolidone. It is divided based on degree of polymerization into soluble PVP and insoluble polyvinyl polypyrrolidone (PVPP). Commercially available PVPs are divided into four viscosity grades by K value (Fikentscher K): K-15, K-30, K-60, K-90, with respective molecular masses of 10000, 40000, 160000, and 360000. K value or relative molecular mass is one of the important factors determining the various properties of PVP.
Polyvinylpyrrolidone is one of the three major new medicinal materials. It can be used for tablets, granules, a cosolvent for injections, glidant for capsules, liquid preparation and dispersant for colorants, stabilizer for enzymes and thermosensitive drugs, precipitant for poorly soluble drugs, and a removal agent and lubricant for eye drops, etc. The combination of PVP with toxins, drugs, and chemical agents can reduce their toxicity. Complexes with iodine are very stable, with good bactericidal effects, reducing toxicity.
Used in industry as a foaming polystyrene additive, gelling agent, stabilizer, fiber treatment agent, paper processing aid, adhesive, and thickener. Some dyes can also be strongly complexed with PVP, which is the basis for polyvinylpyrrolidone PVP as a dye bleaching agent.
Polyvinylpyrrolidone PVP and its copolymer is an important raw material for cosmetics, mainly used for hair styling agents. The film it forms on hair is flexible and shiny, with good combing performance, without attracting dust. Different resins can satisfy different relative humidity and climatic conditions, so it is an indispensable raw material for styling hair cream, hair gel, and mousse. It can also be used as a cosmetic skin care moisturizing agent, base material of grease, hair coloring dispersant, and foam stabilizer. It can improve the consistency of shampoo. Insoluble PVP is a stabilizer for beer, fruit juice, vinegar, wine and so on, improving its clarity, color and taste.

Toxicity

ADI 0-50(FAO/WHO, 2001)
LD50>100g/kg(rats, orally administered)
LD5012g/kg(rats, abdominal injection)
Can be safely used in food (FDA, §173.55, 2000).

Chemical Properties

white to off-white micro-crystalline powder

Uses

PVP (polyvinylpyrrolidone) is a chemical ingredient that, depending on the formulatory requirement, can act as a binder, viscosity controller, emulsion stabilizer, or film former. Its benefits include water and wear resistance, pigment dispersion, a non-greasy feel, and improved stick integrity. PVP is commonly found in waterproof sunscreens, mascaras, and lipsticks in order to improve their wear.

Uses

Polyvinylpyrrolidone (PVP) has been used as a clarifying agent in the food industry.

Uses

Polyvinylpyrrolidone is used in coatings, printing ink, rubber, glass, leather, cosmetics, soaps, plastics, in paper making and as a stabilizer. It acts as a disintegrant in pharmaceutical tablets and as a fining to extract impurities. It is used to remove polyphenols in beer.

Definition

ChEBI: N-Vinyl-2-pyrrolidone is a member of pyrrolidin-2-ones.

Crospovidone Preparation Products And Raw materials

Raw materials

Preparation Products

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Crospovidone Suppliers

Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
CarboMer, Inc.
Tel
--
Fax
--
Email
sales@carbomer.com
Country
United States
ProdList
4026
Advantage
67
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Chembargains
Tel
--
Fax
--
Email
info@chembargains.com
Country
United States
ProdList
178
Advantage
69
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View Lastest Price from Crospovidone manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
Crospovidone 25249-54-1
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-05
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Polyvinylpyrrolidone cross-linked 25249-54-1
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-20
WUHAN FORTUNA CHEMICAL CO., LTD
Product
PVPP 25249-54-1
Price
US $0.00/Kg/Drum
Min. Order
15KG
Purity
medicine grade
Supply Ability
10 TONS
Release date
2021-06-21

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