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Tetraisopropyl methylenediphosphonate

Product Name
Tetraisopropyl methylenediphosphonate
CAS No.
1660-95-3
Chemical Name
Tetraisopropyl methylenediphosphonate
Synonyms
Medronic Acid EP Impurity B;Medronic acid impurity B CRS;Tetraisopropyl Methylenediphonate;Bis(diisopropoxyphosphinyl)methane;Tetrakis(1-methylethyl) Methylenedi;tetra-i-Propylmethylenediphosphonate;TETRAISOPROPYL METHYLENEDIPHOSPHONATE;TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE;TetraisopropylMethylenediphosphonate>Tetra-isopropyl methyldiphosphate ester
CBNumber
CB0747453
Molecular Formula
C13H30O6P2
Formula Weight
344.32
MOL File
1660-95-3.mol
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Tetraisopropyl methylenediphosphonate Property

Boiling point:
155 °C/0.5 mmHg (lit.)
Density 
1.08 g/mL at 25 °C (lit.)
vapor pressure 
0.017Pa at 20℃
refractive index 
n20/D 1.431(lit.)
Flash point:
320 °F
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
color 
Clear Colourless to Yellow
Specific Gravity
1.080
Water Solubility 
Insoluble in water.
BRN 
1080180
InChIKey
FKHXXJRKGVDPQP-UHFFFAOYSA-N
LogP
1.3 at 20℃
CAS DataBase Reference
1660-95-3(CAS DataBase Reference)
NIST Chemistry Reference
Tetraisopropyl methylenediphosphonate(1660-95-3)
EPA Substance Registry System
Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester (1660-95-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26-36-39
WGK Germany 
3
TSCA 
Yes
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001106
Product name
Medronic acid impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001106
Price
$91.8
Updated
2024/03/01
Sigma-Aldrich
Product number
426431
Product name
Tetraisopropyl methylenediphosphonate
Purity
97%
Packaging
25ml
Price
$62.8
Updated
2024/03/01
TCI Chemical
Product number
M1319
Product name
Tetraisopropyl Methylenediphosphonate
Purity
>97.0%(GC)
Packaging
25g
Price
$84
Updated
2024/03/01
Alfa Aesar
Product number
A13484
Product name
Tetraisopropyl methylenediphosphonate, 98%
Packaging
10g
Price
$50.65
Updated
2024/03/01
Alfa Aesar
Product number
A13484
Product name
Tetraisopropyl methylenediphosphonate, 98%
Packaging
50g
Price
$198
Updated
2024/03/01
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Tetraisopropyl methylenediphosphonate Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.

Uses

Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium.
It may be used in the synthesis of the following:

  • tetraisopropyl ethenylidenebisphosphonate.
  • tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
  • tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate

General Description

Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.

Tetraisopropyl methylenediphosphonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tetraisopropyl methylenediphosphonate Suppliers

Jiangxi Kingnord Industrial Limited
Tel
0791-86493591
Fax
+86 791 8649 3642
Email
jeff@kingnord.com
Country
China
ProdList
43
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57
BEIJING EAGLE SKY PHARMATECH CO., LTD
Tel
010-88755821 13911359480
Email
sophia_818@126.com
Country
China
ProdList
274
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55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Suzhou Kaiyuan Minsheng Sci&Tech Corp. Ltd.
Tel
0512-62889106
Fax
0512-62889106
Email
business@minshengpharm.com
Country
China
ProdList
110
Advantage
66
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View Lastest Price from Tetraisopropyl methylenediphosphonate manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-15
Hebei Guanlang Biotechnology Co., Ltd.
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-12-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-12-17

1660-95-3, Tetraisopropyl methylenediphosphonateRelated Search:


  • METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER
  • TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE
  • TETRAISOPROPYL METHYLENEDIPHOSPHONATE
  • Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester
  • Phosphonic acid, methylenedi-, tetraisopropyl ester
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  • tetra-i-Propylmethylenediphosphonate
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  • Tetra isopropyl methylene diphospshonate
  • METHYLENEBIS-PHOSPHONICACID,TETRAKIS(1-METHYLETHYL)ESTER
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  • TetraisopropylMethylenediphosphonate&gt
  • Medronic acid impurity B CRS
  • Tetrakis(1-methylethyl) Methylenedi
  • Tetra-isopropyl methyldiphosphate ester
  • Medronic Acid EP Impurity B
  • 1660-95-3
  • CH2POOCHCH3222
  • C13H30O6P2
  • Organic Building Blocks
  • Phosphonates/Phosphinates
  • Phosphorus Compounds
  • Building Blocks
  • Organic Building Blocks
  • Phosphonates/Phosphinates
  • Phosphorus Compounds