METHYLENEDIPHOSPHONIC ACID

Product Name: METHYLENEDIPHOSPHONIC ACID
CAS No.: 1984-15-2
Chemical Name: METHYLENEDIPHOSPHONIC ACID
Synonyms: MDP;methylenediphosphonate;MEDRONIC ACID;Medronic;medronicaci;MDP~Medronicacid;Medronic acid CRS;Medronic acid - EP;Methanediphosphonic Acid;Methanebisphosphonic Acid
CBNumber: CB6760210
Molecular Formula: CH6O6P2
Formula Weight: 176
MOL File: 1984-15-2.mol

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METHYLENEDIPHOSPHONIC ACID Property

Melting point:: 197-199 °C(lit.)
Boiling point:: 583.2±60.0 °C(Predicted)
Density: 2.111±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO : 250 mg/mL (1420.45 mM; Need ultrasonic)
pka: 1.43±0.10(Predicted)
form: Moist Crystals or Crystalline Powder
color: Blue
Water Solubility: Soluble in water.
Merck: 14,5792
BRN: 1708494
InChI: InChI=1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7)
InChIKey: MBKDYNNUVRNNRF-UHFFFAOYSA-N
SMILES: C(P(O)(O)=O)P(O)(O)=O
CAS DataBase Reference: 1984-15-2(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN 3261 8/PG 3
WGK Germany: -
RTECS: SZ9138000
F: 3
HazardClass: 8
PackingGroup: III
HS Code: 29319019
Toxicity: LD50 in mice, rabbits (mg/kg): 45-50 i.v. (Subramanian, 1975)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M0240000
Product name: Medronic acid
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 20 mg
Price: $236
Updated: 2025/07/31

Sigma-Aldrich

Product number: 64255
Product name: Methylenediphosphonic acid
Purity: for molecular studies & mass spectrometry
Packaging: 1g
Price: $242
Updated: 2025/07/31

Sigma-Aldrich

Product number: 64255
Product name: Methylenediphosphonic acid
Purity: for molecular studies & mass spectrometry
Packaging: 5G
Price: $674.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.41124
Product name: Methylenediphosphonic acid
Purity: for synthesis
Packaging: 1g
Price: $131
Updated: 2025/07/31

Sigma-Aldrich

Product number: 64255
Product name: Methylenediphosphonic acid
Purity: for molecular studies & mass spectrometry
Packaging: 25g
Price: $3640
Updated: 2025/07/31

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METHYLENEDIPHOSPHONIC ACID Chemical Properties,Usage,Production

Chemical Properties

Colourless solid

Uses

Radioactive imaging agent

Uses

Methylenediphosphonic acid is a radioactive compound used for skeletal imaging. MDP has been used as a chelating agent to vary calcium levels in cell culture in a study of caffeine storage in bovine chromaffin cells.

Uses

Methylenediphosphonic acid can be used as a precursor in the synthesis of:

Mesoporous aluminum organophosphonate in the presence of alkyltrimethylammonium as a surfactant.
Tetraester of methylenediphosphonic acids which are used as metal ion extractants for actinides in all oxidation states.

Definition

ChEBI: A 1,1-bis(phosphonic acid) consisting of methane substituted by two phosphonic acid groups.

General Description

MDP (Methylenediphosphonic acid) is a phosphonic analog of ATP.

METHYLENEDIPHOSPHONIC ACID Preparation Products And Raw materials

Raw materials

Tetraisopropyl methylenediphosphonate Hydrochloric acid

Preparation Products

Tiludronic acid

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METHYLENEDIPHOSPHONIC ACID Suppliers

Americas 1 Belgium 3 Canada 2 China 151 Europe 2 France 3 Germany 7 India 5 Italy 1 Japan 3 Slovakia 1 Switzerland 2 United Kingdom 9 United States 26 Global 216

Tianjin Lingxi Technology Co., Ltd

Tel: 022-022-60374912 15822944310
Email: 2725862453@qq.comqq.com
Country: China
ProdList: 498
Advantage: 58

Zhejiang Zetian Fine Chemical Co., Ltd

Tel: 0571-87682782 18957127338
Fax: QQ:3007632051
Email: sales@zetchem.com
Country: China
ProdList: 476
Advantage: 58

Shanghai Langruibang Pharmaceutical Technology Co., Ltd

Tel: 010-88755821 18612220856
Email: marketing@langrb.com
Country: China
ProdList: 413
Advantage: 58

BEIJING EAGLE SKY PHARMATECH CO., LTD

Tel: 010-88755821 13911359480
Email: sophia_818@126.com
Country: China
ProdList: 294
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

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View Lastest Price from METHYLENEDIPHOSPHONIC ACID manufacturers

Shanghai UCHEM Inc.

Product: Methylenebisphosphonic acid 1984-15-2
Price: US $38.00/g
Min. Order: 1g
Purity: 0.98
Supply Ability: 10kg
Release date: 2023-12-20

Career Henan Chemical Co

Product: METHYLENEDIPHOSPHONIC ACID 1984-15-2
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-12

1984-15-2, METHYLENEDIPHOSPHONIC ACIDRelated Search:

METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER TETRAMETHYL METHYLENEDIPHOSPHONATE Orthophosphorus acid Ammonium bisulfite POTASSIUM SULFITE Dibenzyl phosphite Methyl nicotinate NICOTINIC ACID MONONUCLEOTIDE methanedisulphonyl dichloride Methanedisulphonic acid ([1-PHENYL-METH-(E)-YLIDENE]-AMINO)-ACETIC ACID ETHYL ESTER FMOC-CYS(STBU)-OH Linolenic acid TETRAETHYL DIMETHYLAMINOMETHYLENEDIPHOSPHONATE METHYLENEDIPHOSPHONIC ACID TETRAETHYL ESTER,Bis(diethoxyphosphinyl)methane, Methylenediphosphonic acid tetraethylester Tetraethylfluoromethylene-diphosphonate METHYLENEDIPHOSPHONIC ACID Olpadronate Sodium

[α,β-Methylene]diphosphoric acid

Methylenediphosphonic acid, Medronic acid

Medronic acid, Methanediylbis(phosphonic acid)

Methylenediphosphonic acid, methylene diphosphoric acid, Methylenediphosphonic Acid

Phosphonic acid, P , P '-methylenebis-

Methylene diphosphophonic acid

Methylenediphosphonic acid 99%

methylenediphosphonate

PHOSPHONOMETHYLPHOSPHONIC ACID

METHYLENEBISPHOSPHONIC ACID

METHYLENEDIPHOSPHONIC ACID

MDP

MEDRONIC ACID

METHYLENEDIPHOSPHONIC ACID FREE ACID

Methylenediphosphonic acid, 99+%

MDP~Medronicacid

Methanebisphosphonic Acid

Methanediphosphonic Acid

Methylenebiphosphonic Acid

Medronic

bis(dihydroxyphosphoryl)methane

Methylene-1,1-bisphosphonic acid

Phosphonic acid, methylenebis

Phosphonic acid, methylenedi-

Methylenebisphosphonic acid, 99+ %

Methylenebisphosphonic acid, tech. 90 %

Methylenediphosphonic acid, 98 %

MethylenediphosphonicAcid&gt

Medronic acid CRS

METHYLENEDIPHOSPHONIC ACID FOR SYNTHESIS

METHYLENEDIPHOSPHONIC ACID ISO 9001：2015 REACH

Methylenediphosphonic acid, ≥97%

disodium hydrogen (hydrogen phosphonatomethyl)phosphonate

2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL

medronicaci

Phosphonic acid, P,P'-methylenebis-

Clodronate Disodium Impurity 1 (Medronic Acid)

Medronic acid, 10 mM in DMSO

Medronic acid - EP

1984-15-2

CH6O6P2

CH2POOH22

Building Blocks

Radiopharmaceutical Chemistry (Chelating Reagents)

Ligands for Pharmaceutical Research

Organic Building Blocks

Phosphonic/Phosphinic Acids

Phosphorus Compounds

Building Blocks

Chemical Synthesis

Organic Building Blocks

Phosphonic/Phosphinic Acids

Phosphorus Compounds

Analytical Chemistry

Ligands for Pharmaceutical Research

Radiopharmaceutical Chemistry (Chelating Reagents)

Intermediates & Fine Chemicals

Pharmaceuticals