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METHYLENEDIPHOSPHONIC ACID

Product Name
METHYLENEDIPHOSPHONIC ACID
CAS No.
1984-15-2
Chemical Name
METHYLENEDIPHOSPHONIC ACID
Synonyms
MDP;methylenediphosphonate;MEDRONIC ACID;Medronic;medronicaci;MDP~Medronicacid;Medronic acid CRS;Methanediphosphonic Acid;Methanebisphosphonic Acid;METHYLENEDIPHOSPHONIC ACID
CBNumber
CB6760210
Molecular Formula
CH6O6P2
Formula Weight
176
MOL File
1984-15-2.mol
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METHYLENEDIPHOSPHONIC ACID Property

Melting point:
197-199 °C(lit.)
Boiling point:
583.2±60.0 °C(Predicted)
Density 
2.111±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO : 250 mg/mL (1420.45 mM; Need ultrasonic)
pka
1.43±0.10(Predicted)
form 
Moist Crystals or Crystalline Powder
color 
Blue
Water Solubility 
Soluble in water.
Merck 
14,5792
BRN 
1708494
InChIKey
MBKDYNNUVRNNRF-UHFFFAOYSA-N
CAS DataBase Reference
1984-15-2(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3261 8/PG 3
WGK Germany 
-
RTECS 
SZ9138000
F 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29319019
Toxicity
LD50 in mice, rabbits (mg/kg): 45-50 i.v. (Subramanian, 1975)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
64255
Product name
Methylenediphosphonic acid
Purity
for molecular studies & mass spectrometry
Packaging
1g
Price
$228
Updated
2024/03/01
Sigma-Aldrich
Product number
8.41124
Product name
Methylenediphosphonic acid
Purity
for synthesis
Packaging
1g
Price
$183
Updated
2024/03/01
Sigma-Aldrich
Product number
64255
Product name
Methylenediphosphonic acid
Purity
for molecular studies & mass spectrometry
Packaging
5G
Price
$907
Updated
2024/03/01
Sigma-Aldrich
Product number
64255
Product name
Methylenediphosphonic acid
Purity
for molecular studies & mass spectrometry
Packaging
25g
Price
$3540
Updated
2024/03/01
TCI Chemical
Product number
M0843
Product name
Methylenediphosphonic Acid
Purity
>97.0%(T)
Packaging
1g
Price
$77
Updated
2024/03/01
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METHYLENEDIPHOSPHONIC ACID Chemical Properties,Usage,Production

Chemical Properties

Colourless solid

Uses

Radioactive imaging agent

Uses

Methylenediphosphonic acid is a radioactive compound used for skeletal imaging. MDP has been used as a chelating agent to vary calcium levels in cell culture in a study of caffeine storage in bovine chromaffin cells.

Uses

Methylenediphosphonic acid can be used as a precursor in the synthesis of:

  • Mesoporous aluminum organophosphonate in the presence of alkyltrimethylammonium as a surfactant.
  • Tetraester of methylenediphosphonic acids which are used as metal ion extractants for actinides in all oxidation states.

Definition

ChEBI: A 1,1-bis(phosphonic acid) consisting of methane substituted by two phosphonic acid groups.

General Description

MDP (Methylenediphosphonic acid) is a phosphonic analog of ATP.

METHYLENEDIPHOSPHONIC ACID Preparation Products And Raw materials

Raw materials

Tetraisopropyl methylenediphosphonate Hydrochloric acid

Preparation Products

Tiludronic acid
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METHYLENEDIPHOSPHONIC ACID Suppliers

Americas 1 Belgium 3 Canada 2 China 118 Europe 2 France 3 Germany 7 India 5 Italy 1 Japan 3 Slovakia 1 Switzerland 2 United Kingdom 9 United States 26 Global 183
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View Lastest Price from METHYLENEDIPHOSPHONIC ACID manufacturers

Shanghai UCHEM Inc.
Product
Methylenebisphosphonic acid 1984-15-2
Price
US $38.00/g
Min. Order
1g
Purity
0.98
Supply Ability
10kg
Release date
2023-12-20
Shaanxi Dideu Medichem Co. Ltd
Product
Methylenediphosphonic acid 1984-15-2
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50ton
Release date
2020-05-20
Career Henan Chemical Co
Product
METHYLENEDIPHOSPHONIC ACID 1984-15-2
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-12

1984-15-2, METHYLENEDIPHOSPHONIC ACIDRelated Search:

METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER TETRAMETHYL METHYLENEDIPHOSPHONATE Orthophosphorus acid Ammonium bisulfite POTASSIUM SULFITE Dibenzyl phosphite Methyl nicotinate NICOTINIC ACID MONONUCLEOTIDE methanedisulphonyl dichloride Methanedisulphonic acid ([1-PHENYL-METH-(E)-YLIDENE]-AMINO)-ACETIC ACID ETHYL ESTER FMOC-CYS(STBU)-OH Linolenic acid TETRAETHYL DIMETHYLAMINOMETHYLENEDIPHOSPHONATE METHYLENEDIPHOSPHONIC ACID TETRAETHYL ESTER,Bis(diethoxyphosphinyl)methane, Methylenediphosphonic acid tetraethylester Tetraethylfluoromethylene-diphosphonate METHYLENEDIPHOSPHONIC ACID Olpadronate Sodium

  • [α,β-Methylene]diphosphoric acid
  • Methylenediphosphonic acid, Medronic acid
  • Medronic acid, Methanediylbis(phosphonic acid)
  • Methylenediphosphonic acid, methylene diphosphoric acid, Methylenediphosphonic Acid
  • Phosphonic acid, P , P '-methylenebis-
  • Methylene diphosphophonic acid
  • Methylenediphosphonic acid 99%
  • methylenediphosphonate
  • PHOSPHONOMETHYLPHOSPHONIC ACID
  • METHYLENEBISPHOSPHONIC ACID
  • METHYLENEDIPHOSPHONIC ACID
  • MDP
  • MEDRONIC ACID
  • METHYLENEDIPHOSPHONIC ACID FREE ACID
  • Methylenediphosphonic acid, 99+%
  • MDP~Medronicacid
  • Methanebisphosphonic Acid
  • Methanediphosphonic Acid
  • Methylenebiphosphonic Acid
  • Medronic
  • bis(dihydroxyphosphoryl)methane
  • Methylene-1,1-bisphosphonic acid
  • Phosphonic acid, methylenebis
  • Phosphonic acid, methylenedi-
  • Methylenebisphosphonic acid, 99+ %
  • Methylenebisphosphonic acid, tech. 90 %
  • Methylenediphosphonic acid, 98 %
  • MethylenediphosphonicAcid&gt
  • Medronic acid CRS
  • METHYLENEDIPHOSPHONIC ACID FOR SYNTHESIS
  • METHYLENEDIPHOSPHONIC ACID ISO 9001：2015 REACH
  • Methylenediphosphonic acid, ≥97%
  • disodium hydrogen (hydrogen phosphonatomethyl)phosphonate
  • 2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL
  • medronicaci
  • 1984-15-2
  • CH6O6P2
  • CH2POOH22
  • Building Blocks
  • Radiopharmaceutical Chemistry (Chelating Reagents)
  • Ligands for Pharmaceutical Research
  • Organic Building Blocks
  • Phosphonic/Phosphinic Acids
  • Phosphorus Compounds
  • Building Blocks
  • Chemical Synthesis
  • Organic Building Blocks
  • Phosphonic/Phosphinic Acids
  • Phosphorus Compounds
  • Analytical Chemistry
  • Ligands for Pharmaceutical Research
  • Radiopharmaceutical Chemistry (Chelating Reagents)
  • Intermediates & Fine Chemicals
  • Pharmaceuticals