ChemicalBook > CAS DataBase List > TETRAETHYL METHYLENEDIPHOSPHONATE
TETRAETHYL METHYLENEDIPHOSPHONATE
- Product Name
- TETRAETHYL METHYLENEDIPHOSPHONATE
- CAS No.
- 1660-94-2
- Chemical Name
- TETRAETHYL METHYLENEDIPHOSPHONATE
- Synonyms
- 1-[diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethane;1-5kg;NSC 133889;AURORA KA-1506;enediphosphonate;Tenofovir Impurity 183;BIS(DIETHOXYPHOSPHINYL)METHANE;tetraethyl methylenediphosphate;methylenebis(diethylphosphonate);TETRAETHYL METHYLENEDIPHOSPHONATE
- CBNumber
- CB8435905
- Molecular Formula
- C9H22O6P2
- Formula Weight
- 288.21
- MOL File
- 1660-94-2.mol
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TETRAETHYL METHYLENEDIPHOSPHONATE Property
- Boiling point:
- 171-174 °C11 mm Hg(lit.)
- Density
- 1.16 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.442(lit.)
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- form
- Liquid
- Specific Gravity
- 1.160
- color
- Clear yellow to yellow-brown
- Water Solubility
- Slightly miscible with water.
- BRN
- 1813241
- InChIKey
- STJWVOQLJPNAQL-UHFFFAOYSA-N
- CAS DataBase Reference
- 1660-94-2(CAS DataBase Reference)
- EPA Substance Registry System
- Phosphonic acid, methylenebis-, tetraethyl ester (1660-94-2)
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Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- SZ9150000
- Hazard Note
- Corrosive
- TSCA
- Yes
- HS Code
- 29319090
- Toxicity
- mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03139,
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 359181
- Product name
- Tetraethyl methylenediphosphonate
- Purity
- 97%
- Packaging
- 5ml
- Price
- $113
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 359181
- Product name
- Tetraethyl methylenediphosphonate
- Purity
- 97%
- Packaging
- 25ml
- Price
- $476
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A14532
- Product name
- Tetraethyl methylenediphosphonate, 98+%
- Packaging
- 5g
- Price
- $83.4
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A14532
- Product name
- Tetraethyl methylenediphosphonate, 98+%
- Packaging
- 25g
- Price
- $303
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A14532
- Product name
- Tetraethyl methylenediphosphonate, 98+%
- Packaging
- 100g
- Price
- $911.65
- Updated
- 2024/03/01
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TETRAETHYL METHYLENEDIPHOSPHONATE Chemical Properties,Usage,Production
Chemical Properties
clear yellow to yellow-brown liquid
Uses
Tetraethyl methylidenebisphosphonate, can be used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters as potent anti-inflammatory agents. It is also an intermediate for the synthesis of new bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity.
Uses
Reactant for synthesis of:
- Dual substrate-site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
- Unnatural alpha-amino acid derivatives containing gem-biphosphonates
- Biphenyl sulfonylamino Me bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption
- Lycopene via Wittig-Horner reaction
- Alkylaminoethylbisphosphinic acids to target farnesyl diphosphate synthase
- Aromatic bisphosphonates for use as inhibitors of geranylgeranyl diphosphate synthase
Precursor for synthesis of dendritic polyglycerol anions used toward L-selectin inhibition
Synthesis Reference(s)
Synthetic Communications, 20, p. 1865, 1990 DOI: 10.1080/00397919008053112
Tetrahedron Letters, 34, p. 1515, 1993 DOI: 10.1016/S0040-4039(00)60333-7
TETRAETHYL METHYLENEDIPHOSPHONATE Preparation Products And Raw materials
Raw materials
Preparation Products
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TETRAETHYL METHYLENEDIPHOSPHONATE Suppliers
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View Lastest Price from TETRAETHYL METHYLENEDIPHOSPHONATE manufacturers
Hebei Mojin Biotechnology Co., Ltd
- Product
- Tetraethyl methylenediphosphonate 1660-94-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-09-20
Career Henan Chemical Co
- Product
- TETRAETHYL METHYLENEDIPHOSPHONATE 1660-94-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kgs
- Release date
- 2019-12-18
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