Tiludronic acid

Product Name: Tiludronic acid
CAS No.: 89987-06-4
Chemical Name: Tiludronic acid
Synonyms: ACPMD;C08141;ME-3737;C1-TMBP;Tiludronic;TILUDRONIC ACID;Tilundronic Acid;Tiludronic acid disodium;Tiludronate disodium salt hydrate;(4-Chlorophenylthio)methylenediphosphonic acid
CBNumber: CB7374025
Molecular Formula: C7H9ClO6P2S
Formula Weight: 318.61
MOL File: 89987-06-4.mol

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Tiludronic acid Property

Melting point:: 174-177 °C
Boiling point:: 600.7±65.0 °C(Predicted)
Density: 1.82±0.1 g/cm3(Predicted)
storage temp.: room temp
solubility: H2O: >10mg/mL, clear
pka: pK1 10.85; pK2 6.90; pK3 2.95; pK4 1.30(at 25℃)
form: powder
color: white to off-white
Water Solubility: H2O: >10mg/mL, clear

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T4580
Product name: Tiludronate disodium salt hydrate
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $91.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: T4580
Product name: Tiludronate disodium salt hydrate
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $344
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: API0008552
Product name: TILUDRONATE DISODIUM SALT HYDRATE
Purity: 95.00%
Packaging: 10MG
Price: $605.17
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008552
Product name: TILUDRONATE DISODIUM SALT HYDRATE
Purity: 95.00%
Packaging: 50MG
Price: $783.44
Updated: 2021/12/16

AHH

Product number: MT-59523
Product name: Tiludronicacid
Purity: 98%
Packaging: 5g
Price: $910
Updated: 2021/12/16

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Tiludronic acid Chemical Properties,Usage,Production

Chemical Properties

pKl 10.85; pK2 6.90; pK3 2.95; pKa 41.30. Tiludronic Acid Di-tert-butylamine Salt: melting point 253°C (decomposition).

Definition

ChEBI: Tiludronic acid is an organochlorine compound.

Biological Activity

Tiludronate is a bisphosphonate bone resorption inhibitor. Tiludronate inhibits protein-tyrosine-phosphatase, leading to detachment of osteoclasts from the bone surface. It also inhibits the osteoclastic proton pump and is used to tre at Pagetμs disease.

Veterinary Drugs and Treatments

Tiludronate disodium (tiludronic acid) is a bisphosphonate bone resorption inhibitor that is available in some countries for the intravenous treatment of navicular disease in horses. Treatment earlier in the course of the disease apparently results in greater efficacy.
For humans, there is an orally administered FDA-approved product for treating Paget’s disease (osteitis deformans).

Tiludronic acid Preparation Products And Raw materials

Raw materials

Molybdenum disulfide METHYLENEDIPHOSPHONIC ACID

Preparation Products

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Tiludronic acid Suppliers

Canada 1 China 13 Germany 1 United Kingdom 4 United States 8 Global 27

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Zhengzhou Gecko Scientific Inc.

Tel: 0371-63336364 17344886665
Fax: 0371-65511872
Email: 209932355@qq.com
Country: China
ProdList: 489
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15116
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 11438
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Sinoway Industrial co., ltd.

Tel: +86-0592-5800732 +86-13806035118
Fax: 0592-5854960
Email: xie@china-sinoway.com
Country: China
ProdList: 1275
Advantage: 58

Hebei Chuanghai Biotechnology Co., Ltd

Tel: +8615531151365
Email: mina@chuanghaibio.com
Country: China
ProdList: 18126
Advantage: 58

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View Lastest Price from Tiludronic acid manufacturers

Sinoway Industrial co., ltd.

Product: Tiludronic Acid 89987-06-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20tons
Release date: 2024-10-22

Hebei Chuanghai Biotechnology Co., Ltd

Product: Tiludronic acid 89987-06-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-05

89987-06-4, Tiludronic acidRelated Search:

Zoledronic acid CLODRONIC ACID 1-Hydroxyethylidene-1,1-diphosphonic acid Amino tris(methylene phosphonic acid) Etidronate disodium Ethyl 2-(Chlorosulfonyl)acetate Glycine Folic acid Disodium pamidronate 1-tert-Butyl-4-chlorobenzene Diethyl (2-oxopropyl)phosphonate Vinylphosphonic acid Ethylenebis(nitrilodimethylene)tetraphosphonic acid Citric acid Ascoric Acid 2,4-Dinitrochlorobenzene 2-Chlorophenyl cyclopentyl ketone METHYLENEDIPHOSPHONIC ACID

[[(4-Chlorophenyl)thio]methylene]bisphosphonic acid

ACPMD

C1-TMBP

ME-3737

Tiludronate disodium salt hydrate

Tiludronic acid disodium

Tilundronic Acid

TILUDRONIC ACID

C08141

[[(4-Chlorophenyl)thio]methylene]bisphosphonic acid disodium salt hydrate

Tiludronic

(4-Chlorophenylthio)methylenediphosphonic acid

Phosphonic acid, P,P'-[[(4-chlorophenyl)thio]methylene]bis-

89987-06-4

C7H9ClO6P2S

API