ChemicalBook > CAS DataBase List > Tetraisopropyl methylenediphosphonate

Tetraisopropyl methylenediphosphonate

Product Name
Tetraisopropyl methylenediphosphonate
CAS No.
1660-95-3
Chemical Name
Tetraisopropyl methylenediphosphonate
Synonyms
Medronic Acid EP Impurity B;Medronic acid impurity B CRS;Tetraisopropyl Methylenediphonate;Bis(diisopropoxyphosphinyl)methane;Tetrakis(1-methylethyl) Methylenedi;tetra-i-Propylmethylenediphosphonate;TETRAISOPROPYL METHYLENEDIPHOSPHONATE;TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE;TetraisopropylMethylenediphosphonate>Tetra-isopropyl methyldiphosphate ester
CBNumber
CB0747453
Molecular Formula
C13H30O6P2
Formula Weight
344.32
MOL File
1660-95-3.mol
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Tetraisopropyl methylenediphosphonate Property

Boiling point:
155 °C/0.5 mmHg (lit.)
Density 
1.08 g/mL at 25 °C (lit.)
vapor pressure 
0.017Pa at 20℃
refractive index 
n20/D 1.431(lit.)
Flash point:
320 °F
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
color 
Clear Colourless to Yellow
Specific Gravity
1.080
Water Solubility 
Insoluble in water.
BRN 
1080180
InChIKey
FKHXXJRKGVDPQP-UHFFFAOYSA-N
LogP
1.3 at 20℃
CAS DataBase Reference
1660-95-3(CAS DataBase Reference)
NIST Chemistry Reference
Tetraisopropyl methylenediphosphonate(1660-95-3)
EPA Substance Registry System
Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester (1660-95-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26-36-39
WGK Germany 
3
TSCA 
Yes
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001106
Product name
Medronic acid impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001106
Price
$91.8
Updated
2024/03/01
Sigma-Aldrich
Product number
426431
Product name
Tetraisopropyl methylenediphosphonate
Purity
97%
Packaging
25ml
Price
$62.8
Updated
2024/03/01
TCI Chemical
Product number
M1319
Product name
Tetraisopropyl Methylenediphosphonate
Purity
>97.0%(GC)
Packaging
25g
Price
$84
Updated
2024/03/01
Alfa Aesar
Product number
A13484
Product name
Tetraisopropyl methylenediphosphonate, 98%
Packaging
10g
Price
$50.65
Updated
2024/03/01
Alfa Aesar
Product number
A13484
Product name
Tetraisopropyl methylenediphosphonate, 98%
Packaging
50g
Price
$198
Updated
2024/03/01
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Tetraisopropyl methylenediphosphonate Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.

Uses

Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium.
It may be used in the synthesis of the following:

  • tetraisopropyl ethenylidenebisphosphonate.
  • tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
  • tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate

General Description

Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.

Tetraisopropyl methylenediphosphonate Preparation Products And Raw materials

Raw materials

Preparation Products

METHYLENEDIPHOSPHONIC ACID
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Tetraisopropyl methylenediphosphonate Suppliers

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View Lastest Price from Tetraisopropyl methylenediphosphonate manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-15
Hebei Guanlang Biotechnology Co., Ltd.
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-12-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-12-17

1660-95-3, Tetraisopropyl methylenediphosphonateRelated Search:

N,N-Dimethylallylamine Triisopropyl phosphite 2-Hydroxypropyl methacrylate 3-Methyl-2-butanone Titanium tetraisopropanolate Isopropyl myristate METHYLENEDIPHOSPHONIC ACID ALLYL METHYL ETHER Cyclopropyl methyl ketone methanedisulphonyl dichloride TETRAMETHYL METHYLENEDIPHOSPHONATE Orthophosphorus acid Methanedisulphonic acid Methylene dithiocyanate TETRAISOPROPYL ORTHOSILICATE TETRAISOPROPYL 1,2-ETHYLENEDIPHOSPHONATE TETRAISOPROPYL METHYLENEDIPHOSPHONATE, 9 7% 2-METHYLPENTANE

  • METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER
  • TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE
  • TETRAISOPROPYL METHYLENEDIPHOSPHONATE
  • Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester
  • Phosphonic acid, methylenedi-, tetraisopropyl ester
  • phosphonicacid,methylenebis-,tetrakis(1-methylethyl)ester
  • tetra-i-Propylmethylenediphosphonate
  • Methanediphosphonic acid tetraisopropyl ester
  • Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetrakis(1-methylethyl) ester
  • Tetra isopropyl methylene diphospshonate
  • METHYLENEBIS-PHOSPHONICACID,TETRAKIS(1-METHYLETHYL)ESTER
  • METHYLENEPHOSPHONIC ACID TETRAISOPROPYL ESTER
  • Tetraisopropyl(methylene)bisphosphonate, 98 %
  • 2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane
  • Bis(diisopropoxyphosphinyl)methane
  • Tetraisopropyl Methylenediphonate
  • Tetraisopropyl methylenediphosphonate,98%
  • Tetraisopropyl methylenediphosphonatedisc 6/01
  • Tetraisopropyl Methylenediphosphonate(for DisodiuM clodronate)
  • Tetraisopropyl methylenediphosphonate 97%
  • Bis(propan-2-yl) {[bis(propan-2-yloxy)-phosphoryl]methyl}phosphonate
  • TetraisopropylMethylenediphosphonate&gt
  • Medronic acid impurity B CRS
  • Tetrakis(1-methylethyl) Methylenedi
  • Tetra-isopropyl methyldiphosphate ester
  • Medronic Acid EP Impurity B
  • 1660-95-3
  • CH2POOCHCH3222
  • C13H30O6P2
  • Organic Building Blocks
  • Phosphonates/Phosphinates
  • Phosphorus Compounds
  • Building Blocks
  • Organic Building Blocks
  • Phosphonates/Phosphinates
  • Phosphorus Compounds