ChemicalBook > CAS DataBase List > Tetraisopropyl methylenediphosphonate

Tetraisopropyl methylenediphosphonate

Product Name
Tetraisopropyl methylenediphosphonate
CAS No.
1660-95-3
Chemical Name
Tetraisopropyl methylenediphosphonate
Synonyms
Medronic Acid EP Impurity B;Medronic acid impurity B CRS;Tetraisopropyl Methylenediphonate;Bis(diisopropoxyphosphinyl)methane;Tetrakis(1-methylethyl) Methylenedi;tetra-i-Propylmethylenediphosphonate;TETRAISOPROPYL METHYLENEDIPHOSPHONATE;TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE;TetraisopropylMethylenediphosphonate>Tetra-isopropyl methyldiphosphate ester
CBNumber
CB0747453
Molecular Formula
C13H30O6P2
Formula Weight
344.32
MOL File
1660-95-3.mol
More
Less

Tetraisopropyl methylenediphosphonate Property

Boiling point:
155 °C/0.5 mmHg (lit.)
Density 
1.08 g/mL at 25 °C (lit.)
vapor pressure 
0.017Pa at 20℃
refractive index 
n20/D 1.431(lit.)
Flash point:
320 °F
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
color 
Clear Colourless to Yellow
Specific Gravity
1.080
Water Solubility 
Insoluble in water.
BRN 
1080180
InChIKey
FKHXXJRKGVDPQP-UHFFFAOYSA-N
LogP
1.3 at 20℃
CAS DataBase Reference
1660-95-3(CAS DataBase Reference)
NIST Chemistry Reference
Tetraisopropyl methylenediphosphonate(1660-95-3)
EPA Substance Registry System
Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester (1660-95-3)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26-36-39
WGK Germany 
3
TSCA 
Yes
HS Code 
29319090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001106
Product name
Medronic acid impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001106
Price
$91.8
Updated
2024/03/01
Sigma-Aldrich
Product number
426431
Product name
Tetraisopropyl methylenediphosphonate
Purity
97%
Packaging
25ml
Price
$62.8
Updated
2024/03/01
TCI Chemical
Product number
M1319
Product name
Tetraisopropyl Methylenediphosphonate
Purity
>97.0%(GC)
Packaging
25g
Price
$84
Updated
2024/03/01
Alfa Aesar
Product number
A13484
Product name
Tetraisopropyl methylenediphosphonate, 98%
Packaging
10g
Price
$50.65
Updated
2024/03/01
Alfa Aesar
Product number
A13484
Product name
Tetraisopropyl methylenediphosphonate, 98%
Packaging
50g
Price
$198
Updated
2024/03/01
More
Less

Tetraisopropyl methylenediphosphonate Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.

Uses

Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium.
It may be used in the synthesis of the following:

  • tetraisopropyl ethenylidenebisphosphonate.
  • tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
  • tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate

General Description

Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.

Tetraisopropyl methylenediphosphonate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tetraisopropyl methylenediphosphonate Suppliers

HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Alfa Chemistry
Tel
Email
info@alfa-chemistry.com
Country
United States
ProdList
2344
Advantage
58
Digital Specialty Chemicals (DSC)
Tel
--
Fax
--
Email
dsc_info@entegris.com
Country
United States
ProdList
119
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
Parchem Fine & Specialty Chemicals
Tel
--
Fax
--
Email
info@parchem.com
Country
United States
ProdList
1031
Advantage
58
Ambeed, Inc.
Tel
--
Fax
--
Email
info@ambeed.com
Country
United States
ProdList
502
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Solvay America Inc.
Tel
--
Fax
--
Email
Jesse.Hu@Solvay.com
Country
United States
ProdList
13
Advantage
58
Glentham Life Sciences Ltd
Tel
--
Fax
--
Email
info@glentham.com
Country
United States
ProdList
2026
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)
Tel
--
Fax
--
Email
nfo@synquestlabs.com
Country
United States
ProdList
1897
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
vulcanchem
Tel
--
Fax
--
Email
info@vulcanchem.com
Country
United States
ProdList
268
Advantage
58
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Accela ChemBio Inc.
Tel
--
Fax
--
Email
info@accelachem.com
Country
United States
ProdList
1054
Advantage
50
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
Cytec Industries Inc.
Tel
--
Fax
--
Email
custinfo@cytec.com
Country
United States
ProdList
88
Advantage
81
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Dishman Europe Ltd
Tel
--
Fax
--
Email
info@dishman-europe.com
Country
United States
ProdList
622
Advantage
58
Digital Specialty Chemicals, Inc.
Tel
--
Fax
--
Email
sales@digitalchem.com
Country
United States
ProdList
710
Advantage
85
Prime Organics, Inc.
Tel
--
Fax
--
Email
info@primeorg.com
Country
United States
ProdList
613
Advantage
51
More
Less

View Lastest Price from Tetraisopropyl methylenediphosphonate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-10
Hebei Mojin Biotechnology Co., Ltd
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
Tetraisopropyl methylenediphosphonate 1660-95-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

1660-95-3, Tetraisopropyl methylenediphosphonateRelated Search:


  • METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER
  • TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE
  • TETRAISOPROPYL METHYLENEDIPHOSPHONATE
  • Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester
  • Phosphonic acid, methylenedi-, tetraisopropyl ester
  • phosphonicacid,methylenebis-,tetrakis(1-methylethyl)ester
  • tetra-i-Propylmethylenediphosphonate
  • Methanediphosphonic acid tetraisopropyl ester
  • Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetrakis(1-methylethyl) ester
  • Tetra isopropyl methylene diphospshonate
  • METHYLENEBIS-PHOSPHONICACID,TETRAKIS(1-METHYLETHYL)ESTER
  • METHYLENEPHOSPHONIC ACID TETRAISOPROPYL ESTER
  • Tetraisopropyl(methylene)bisphosphonate, 98 %
  • 2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane
  • Bis(diisopropoxyphosphinyl)methane
  • Tetraisopropyl Methylenediphonate
  • Tetraisopropyl methylenediphosphonate,98%
  • Tetraisopropyl methylenediphosphonatedisc 6/01
  • Tetraisopropyl Methylenediphosphonate(for DisodiuM clodronate)
  • Tetraisopropyl methylenediphosphonate 97%
  • Bis(propan-2-yl) {[bis(propan-2-yloxy)-phosphoryl]methyl}phosphonate
  • TetraisopropylMethylenediphosphonate&gt
  • Medronic acid impurity B CRS
  • Tetrakis(1-methylethyl) Methylenedi
  • Tetra-isopropyl methyldiphosphate ester
  • Medronic Acid EP Impurity B
  • 1660-95-3
  • CH2POOCHCH3222
  • C13H30O6P2
  • Organic Building Blocks
  • Phosphonates/Phosphinates
  • Phosphorus Compounds
  • Building Blocks
  • Organic Building Blocks
  • Phosphonates/Phosphinates
  • Phosphorus Compounds