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BERBERINE CHLORIDE

Product Name
BERBERINE CHLORIDE
CAS No.
141433-60-5
Chemical Name
BERBERINE CHLORIDE
Synonyms
BERBERINE HCL;BBR;BERBERIN HCL;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;Berberine chloride hydrate 97%;CI 75160;UMBELLATINE;BERBERINE CHLORIDE;TIMTEC-BB SBB006488;LABOTEST-BB LT00440956
CBNumber
CB0758776
Molecular Formula
C20H20ClNO5
Formula Weight
389.83
MOL File
141433-60-5.mol
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BERBERINE CHLORIDE Property

Melting point:
204-206 °C (dec.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
Colour Index 
75160
color 
Pale Yellow to Yellow
Water Solubility 
Soluble in water.
Sensitive 
Light Sensitive
Merck 
14,1154
BRN 
3836585
Stability:
Hygroscopic
InChIKey
VKJGBAJNNALVAV-UHFFFAOYSA-M
CAS DataBase Reference
141433-60-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
WGK Germany 
2
RTECS 
DR9866400
3-10
TSCA 
Yes
HS Code 
29399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
14050
Product name
Berberine chloride hydrate
Purity
technical, ≥90% (AT)
Packaging
10g
Price
$67.7
Updated
2024/03/01
Sigma-Aldrich
Product number
14050
Product name
Berberine chloride hydrate
Purity
technical, ≥90% (AT)
Packaging
50g
Price
$82
Updated
2024/03/01
TCI Chemical
Product number
B0450
Product name
Berberine Chloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
B0450
Product name
Berberine Chloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$77
Updated
2024/03/01
Alfa Aesar
Product number
L03807
Product name
Berberine chloride hydrate, 97%, water <17%
Packaging
5g
Price
$28.65
Updated
2024/03/01
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BERBERINE CHLORIDE Chemical Properties,Usage,Production

Description

Berberine chloride occurs together with Neprotine (q.v.) in Berberis insignis Hook, B. umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.). It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.) and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p. 265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p. 213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.). Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the ethylimide, m.p. 90°C.

Uses

Berberine chloride is mainly used to treat gastroenteritis, dysentery and other intestinal infections, conjunctivitis and suppurative otitis media.

General Description

Berberine chloride is an alkaloid with antibiotic properties. Berberine chloride induces reactive oxygen species (ROS) production and inhibits DNA topoisomerase. It has anti-tumor properties.

References

Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944)

BERBERINE CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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BERBERINE CHLORIDE Suppliers

Shanghai zhiping biology science and technology co., ltd
Tel
13621780388
Email
494972302@qq.com
Country
China
ProdList
42
Advantage
58
Shanghai Jiaoze Industrial Co., LTD
Tel
021-37318802 18616909727
Fax
021-37318802
Email
liangpanpan@sh-jiaoze.com
Country
China
ProdList
117
Advantage
58
Changzhou jinhan pharmaceutical technology co., LTD
Tel
13917833665
Email
lyg@world-goldpharma.com
Country
China
ProdList
151
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
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View Lastest Price from BERBERINE CHLORIDE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Berberine HCl 141433-60-5
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-12-10
Hebei Chuanghai Biotechnology Co,.LTD
Product
BERBERINE CHLORIDE 141433-60-5
Price
US $10.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2024-08-21
Hebei Kingfiner Technology Development Co.Ltd
Product
BERBERINE CHLORIDE 141433-60-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2024-06-17

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