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2,3,5-Tribromothiophene

Product Name
2,3,5-Tribromothiophene
CAS No.
3141-24-0
Chemical Name
2,3,5-Tribromothiophene
Synonyms
S0507;2,3,5-Tribromothiop;2,3,5-Tribromothioph;2,3,5-Triibromothiophn;2,3,5-TRIBROMOTHIOPHENE;2,3,5-tribromo-thiophen;2,3,5-Tribromothiophenem;2,3,5-Triibromothiophene;Thiophene,2,3,5-tribromo-;2,3,5-Tribromothiophene,98%
CBNumber
CB0764357
Molecular Formula
C4HBr3S
Formula Weight
320.83
MOL File
3141-24-0.mol
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2,3,5-Tribromothiophene Property

Melting point:
25-28 °C (lit.)
Boiling point:
120 °C/11 mmHg (lit.)
Density 
2.483 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.664(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
form 
solid
Specific Gravity
2.483
color 
White or Colorless to Yellow
BRN 
111486
InChI
InChI=1S/C4HBr3S/c5-2-1-3(6)8-4(2)7/h1H
InChIKey
SKDNDSLDRLEELJ-UHFFFAOYSA-N
SMILES
C1(Br)SC(Br)=CC=1Br
CAS DataBase Reference
3141-24-0(CAS DataBase Reference)
EPA Substance Registry System
Thiophene, 2,3,5-tribromo- (3141-24-0)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
36/37/39-26
RIDADR 
UN 2929 6.1/PG 2
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HazardClass 
6.1
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T0956
Product name
2,3,5-Tribromothiophene
Purity
>98.0%(GC)
Packaging
25g
Price
$87
Updated
2025/07/31
TCI Chemical
Product number
T0956
Product name
2,3,5-Tribromothiophene
Purity
>98.0%(GC)
Packaging
250g
Price
$454
Updated
2025/07/31
TRC
Product number
T896753
Product name
2,3,5-Tribromothiophene
Packaging
250mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR10149
Product name
2,3,5-Tribromothiophene
Packaging
100g
Price
$56
Updated
2021/12/16
AK Scientific
Product number
J90981
Product name
2,3,5-Tribromothiophene
Packaging
100g
Price
$60
Updated
2021/12/16
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2,3,5-Tribromothiophene Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

2,3,5-Tribromothiophene was used in the synthesis of 2,5-bis(dicyanomethylene)-3-bromo-2,5-dihydrothiophene.

Synthesis

188290-36-0

3141-24-0

a. Add 35 L of chloroform, thiophene and 16.8 kg of copper bromide to Reactor 1 and stir for 10 minutes. Reactor 1 was cooled to -5°C, followed by the slow dropwise addition of 65.0 kg of bromine. b. Upon start of the reaction, pass air or oxygen into Reactor 1. After completion of the bromine addition, the reaction was slowly heated to reflux and the reaction gas was condensed through reflux condenser 8 and returned to reactor 1. The reaction lasted for 3.5 hours and then cooled to 23-25°C. c. A drop of bromine was added to reactor 1 and the reaction was cooled to -5°C for 10 minutes. c. Add 10 L of 0.05 mol/L ethanol solution of sodium hydroxide dropwise to reaction kettle 1 to decompose unreacted bromine and stir for 30 min. d. Transfer the reaction mixture to autoclave 2, add 35 L of water, stir for 30 minutes and leave to stand. The lower organic phase was separated for atmospheric pressure distillation. During distillation, the solvent was first recovered by condensing through distillation condenser 9 and distillation condenser 10, and the solvent was recovered to solvent recovery tank 4. Subsequently, the distillation was carried out under reduced pressure at 15 mmHg, and again condensed through distillation condenser 9 and distillation condenser 10, and the fraction at 112-116 °C/15 mmHg was collected to the product fraction collection tank 5, which ultimately yielded 52.6 kg of colorless liquid 2,3,5-tribromo thiophene.

References

[1] European Journal of Inorganic Chemistry, 2001, # 1, p. 233 - 238
[2] European Journal of Organic Chemistry, 2017, vol. 2017, # 4, p. 861 - 870
[3] Synthetic Communications, 1988, vol. 18, # 15, p. 1763 - 1764
[4] European Journal of Organic Chemistry, 2008, # 5, p. 801 - 804
[5] Chinese Journal of Chemistry, 2014, vol. 32, # 4, p. 365 - 369

2,3,5-Tribromothiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,5-Tribromothiophene Suppliers

Cenik Chemicals
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View Lastest Price from 2,3,5-Tribromothiophene manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
2,3,5-Tribromothiophene 3141-24-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-04-18
Henan Fengda Chemical Co., Ltd
Product
2,3,5-Tribromothiophene 3141-24-0
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Zhuozhou Wenxi import and Export Co., Ltd
Product
2,3,5-Tribromothiophene 3141-24-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

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