DISPASE
Description Source- Product Name
- DISPASE
- CAS No.
- 9068-59-1
- Chemical Name
- DISPASE
- Synonyms
- DISPASE;CALPAIN;PRONASE E;DISPASE I;danbaimei;DISPASE II;Serratidase;EC: 3.4.24.4;IUB: 3.4.24.6;NEUTRAL PROTEASE
- CBNumber
- CB0768845
- Formula Weight
- 0
- MOL File
- Mol file
DISPASE Property
- storage temp.
- −20°C
- form
- lyophilized powder
- color
- Light yellow to brown
- PH
- 6-7 (20°C, 10g/L in H2O)
- CAS DataBase Reference
- 9068-59-1
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-42
- Safety Statements
- 22-24-26-36/37
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P285In case of inadequate ventilation wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 1.07433
- Product name
- Pronase E
- Packaging
- 5G
- Price
- $628
- Updated
- 2025/07/31
- Product number
- 1.07433
- Product name
- Pronase E
- Packaging
- 1G
- Price
- $175
- Updated
- 2023/06/20
DISPASE Chemical Properties,Usage,Production
Uses
Pronase E (from Streptomyces griseus) 4,000,000 PU/g for biochemistry EC 3.4.24.4. CAS 9036-06-0, pH 6?-?7 (10?g/l, H?O, 20?°C).
General Description
from Streptomyces griseus 4,000,000 PU/g for biochemistry EC 3.4.24.4
Description
Neutral Protease (Dispase®) is isolated from Bacillus polymyxa and is a mild proteolytic enzyme that separates the epidermis from dermis by cleaving the basement membrane zone of the skin while preserving the viability of epithelial sheets. This enzyme is effective at cleaving fibronectin and type IV collagen in the lamina densa of skin. It will not cleave serum albumin, transferrin, laminin, type V collagen, or anchoring fibrils containing type VII collagen. As described in the expired U.S. Patent 4,304,866, Neutral Protease (Dispase®) is activated by metallic ions such as Ca++, Mn++, Mg++, Fe++, Fe+++, and Al+++ and is inhibited by metal-chelating agents such as ethylenediaminetetraacetic acid (EDTA), citric acid, o-phenanthroline, 2,2'-dipyridyl and sodium fluoride, and oxidizing agents such as N-bromosuccinimide (NBS) and iodine. Neutral Protease (Dispase®) is used at various concentrations for tissue dissociation, generally ranging from 0.6 to 2.4 U/ml for various time points depending on the desired effect. Concentrations higher than 2.4 U/ml are not recommended.
Source
B. polymyxa
DISPASE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DISPASE manufacturers
- Product
- Dispase 9068-59-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98.0%
- Supply Ability
- 1kg/month
- Release date
- 2021-08-26
- Product
- DISPASE 9068-59-1
- Price
- US $127.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 52000T
- Release date
- 2021-06-08
- Product
- DISPASE 9068-59-1
- Price
- US $40.00/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 5000KG
- Release date
- 2020-11-11